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Stage IVA Lung Cancer clinical trials

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NCT ID: NCT04005144 Terminated - Clinical trials for Lung Non-Small Cell Carcinoma

Brigatinib and Binimetinib in Treating Patients With Stage IIIB-IV ALK or ROS1-Rearranged Non-small Cell Lung Cancer

Start date: February 25, 2020
Phase: Phase 1
Study type: Interventional

This phase I trial studies the side effects and best dose of brigatinib and binimetinib in treating patients with stage IIIB-IV non-small cell lung cancer and a type of gene mutation called a rearrangement in the ALK or ROS1 genes. Brigatinib and binimetinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.