Stage IV Lung Cancer AJCC v8 Clinical Trial
Official title:
A Phase II Randomized Study of Ramucirumab Plus MK3475 (Pembrolizumab) Versus Standard of Care for Patients Previously Treated With Immunotherapy for Stage IV or Recurrent Non-Small Cell Lung Cancer (Lung-MAP Non-Matched Sub-Study)
Verified date | December 2023 |
Source | SWOG Cancer Research Network |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
This phase II Lung-MAP non-Match treatment trial studies how well ramucirumab and pembrolizumab work versus standard of care in treating patients with non-small cell lung cancer that is stage IV or has come back. Immunotherapy with monoclonal antibodies, such as ramucirumab and pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Drugs used in standard of care chemotherapy for non-small cell lung cancer, such as docetaxel, gemcitabine hydrochloride, and pemetrexed, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving ramucirumab and pembrolizumab together may work better in treating patients with non-small lung cancer compared to standard of care.
Status | Active, not recruiting |
Enrollment | 166 |
Est. completion date | July 15, 2024 |
Est. primary completion date | April 14, 2022 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - Patients must have been assigned to S1800A by the Southwest Oncology Group (SWOG) Statistics and Data Management Center (SDMC). Patients who were screened under S1400 (legacy screening/pre-screening study) must have had prior PD-L1 testing by the Dako 22C3 PharmDx immunohistochemistry (IHC) assay, and must have results available for stratification purposes - Patients must not have EGFR sensitizing mutations, EGFR T790M mutation, ALK gene fusion, ROS 1 gene rearrangement, and BRAF V600E mutation unless they have progressed following all standard of care targeted therapy - Patients must not have an active autoimmune disease that has required systemic treatment in past two years (i.e., with use of disease modifying agents, corticosteroids or immunosuppressive drugs). Replacement therapy (e.g., thyroxine, insulin, or physiologic corticosteroid replacement therapy for adrenal or pituitary insufficiency) is not considered a form of systemic treatment and is allowed - Patients must not have any history of primary immunodeficiency - Patients must not have experienced the following: - Any grade 3 or worse immune-related adverse event (irAE). Exception: asymptomatic nonbullous/nonexfoliative rash - Any unresolved grade 2 irAE - Any toxicity that led to permanent discontinuation of prior anti-PD-1/PD-L1 immunotherapy - Exception to the above: Toxicities of any grade that requires replacement therapy and has stabilized on therapy (e.g., thyroxine, insulin, or physiologic corticosteroid replacement therapy for adrenal or pituitary insufficiency) are allowed - Patients must not have any history of organ transplant that requires use of immunosuppressives - Patients must not have clinical signs or symptoms of active tuberculosis infection - Patients must not have history of (non-infectious) pneumonitis that required steroids or current pneumonitis/interstitial lung disease - Patients must not have had a serious or nonhealing wound, ulcer, or bone fracture within 28 days prior to sub-study randomization - Patients must not have a history of gastrointestinal perforation or fistula within six months prior to sub-study randomization - Patients must not have grade 3-4 gastrointestinal bleeding (defined by National Cancer Institute [NCI] Common Terminology Criteria for Adverse Events [CTCAE] version [v] 5) within three months prior to sub-study randomization - Patients must not have any known allergy or reaction to any component of the investigational and standard of care formulations - Patients must not have any grade III/IV cardiac disease as defined by the New York Heart Association criteria (i.e., patients with cardiac disease resulting in marked limitation of physical activity or resulting in inability to carry on any physical activity without discomfort), unstable angina pectoris, and myocardial infarction within six months prior to sub-study randomization, or serious uncontrolled cardiac arrhythmia - Patients must not have experienced any arterial thromboembolic events, including but not limited to myocardial infarction, transient ischemic attack, cerebrovascular accident, or unstable angina, within six months prior to sub-study randomization - Patients must not have documented evidence of acute hepatitis or have an active or uncontrolled infection - Patients with known human immunodeficiency virus (HIV) infection are eligible, provided they are on effective anti-retroviral therapy and have undetectable viral load at their most recent viral load test and within 6 months prior to randomization - Patients with evidence of chronic hepatitis B virus (HBV) infection are eligible provided viral load is undetectable on suppressive therapy, if indicated - Patients with a history of hepatitis C virus (HCV) infection must have been treated and cured. For patients with HCV infection who are currently on treatment, they are eligible if they have an undetectable HCV viral load - Patients must not have undergone major surgery within 28 days prior to sub-study randomization, or subcutaneous venous access device placement within 7 days prior to randomization. Any patient with postoperative bleeding complications or wound complications from a surgical procedure performed in the last two months should be excluded. The patient must not have elective or planned major surgery to be performed during the course of the clinical trial - Patients must not have gross hemoptysis within two months of sub-study randomization (defined as bright red blood or >= 1/2 teaspoon) or with radiographic evidence of intratumor cavitation or has radiologically documented evidence of major blood vessel invasion or encasement by cancer - No other prior malignancy is allowed except for the following: adequately treated basal cell or squamous cell skin cancer, in situ cervical cancer, adequately treated stage I or II cancer from which the patient is currently in complete remission, or any other cancer from which the patient has been disease free for five years - Patients must not have been diagnosed with venous thrombosis less than 3 months prior to randomization. Patients with venous thrombosis diagnosed more than 3 months prior to randomization must be on stable doses of anticoagulants - Patients must not have any of following: - Cirrhosis at a level of Child-Pugh B (or worse); - Cirrhosis (any degree) and a history of hepatic encephalopathy; or - Clinically meaningful ascites resulting from cirrhosis. Clinically meaningful ascites is defined as ascites from cirrhosis requiring diuretics or paracentesis - Patients must have received exactly one line of anti-PD-1 or anti-PD-L1 therapy for at least 84 days as their most recent line of therapy, either alone or in combination with platinum-based chemotherapy. Patients must have experienced disease progression during or after this regimen. Patients whose most recent line of therapy was anti-PD-1 or anti-PD-L1 monotherapy must have also experienced disease progression during or after prior platinum-based chemotherapy - Patients must not have received any prior systemic therapy (systemic chemotherapy, immunotherapy or investigational drug) within 21 days prior to substudy randomization. Patients must have recovered (=< grade 1) from any side effects of prior therapy, except for alopecia. Patients must not have received any radiation therapy within 14 days prior to sub-study randomization - Patients must not have received nitrosoureas or mitomycin-c within 42 days prior to sub-study randomization - Patients must not have received systemic treatment with corticosteroids (> 10 mg daily prednisone or equivalent) or other immunosuppressive medications within seven days prior to sub-study randomization. Inhaled or topical steroids, and adrenal replacement doses =< 10 mg daily prednisone or equivalent are permitted in the absence of active autoimmune disease - Patients must not have received a live attenuated vaccination within 28 days prior to sub-study randomization - Patients must not be planning to receive any concurrent chemotherapy, immunotherapy, biologic or hormonal therapy for cancer treatment while receiving treatment on this study. Concurrent use of hormones for non-cancer-related conditions (e.g., insulin for diabetes and hormone replacement therapy) is acceptable - Patients must not be receiving chronic antiplatelet therapy, including aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs, including ibuprofen, naproxen, and others), dipyridamole or clopidogrel, or similar agents within 7 days prior to randomization. Once-daily aspirin use (maximum dose 325 mg/day) is permitted - Patient must not have received radiotherapy within 14 days before the first dose of study treatment or received lung radiation therapy of > 30 Gy within 6 months before the first dose of study treatment - Note: Participants must have recovered from all radiation-related toxicities to grade 1 or less, not require corticosteroids, and not have had radiation pneumonitis - Patients must have measurable disease documented by computed tomography (CT) or magnetic resonance imaging (MRI). The CT from a combined positron emission tomography (PET)/CT may be used to document only non-measurable disease unless it is of diagnostic quality. Measurable disease must be assessed within 28 days prior to substudy randomization. Pleural effusions, ascites and laboratory parameters are not acceptable as the only evidence of disease. Non-measurable disease must be assessed within 42 days prior to sub-study randomization. All disease must be assessed and documented on the Baseline Tumor Assessment Form. Patients whose only measurable disease is within a previous radiation therapy port must demonstrate clearly progressive disease (in the opinion of the treating investigator) prior to sub-study randomization. CT and MRI scans must be submitted for central review via transfer of images and data (TRIAD) - Patients must have a CT or MRI scan of the brain to evaluate for central nervous system (CNS) disease within 42 days prior to sub-study randomization. Patient must not have leptomeningeal disease, spinal cord compression or brain metastases unless: (1) metastases have been locally treated and have remained clinically controlled and asymptomatic for at least 14 days following treatment, and prior to sub-study randomization, AND (2) patient has no residual neurological dysfunction and has been off corticosteroids for at least seven days prior to sub-study randomization - Absolute neutrophil count (ANC) >= 1,500/mcl (obtained within 28 days prior to sub-study randomization) - Platelet count >= 100,000 mcl (obtained within 28 days prior to sub-study randomization) - Hemoglobin >= 9 g/dL (obtained within 28 days prior to sub-study randomization) - Serum bilirubin =< institutional upper limit of normal (IULN) within 28 days prior to sub-study randomization. For patients with liver metastases, bilirubin must be =< 5 x IULN; and either - Alanine aminotransferase (ALT) or aspartate aminotransferase (AST) =< 2 x IULN within 28 days prior to sub-study randomization (if both ALT and AST are done, both must be < 2 IULN). For patients with liver metastases, either ALT or AST must be =< 5 x IULN (if both ALT and AST are done, both must be =< 5 x IULN) - Serum creatinine =< the IULN OR calculated creatinine clearance >= 50 mL/min using the Cockcroft-Gault formula. This specimen must have been drawn and processed within 28 days prior to sub-study randomization - Patients? urinary protein must be =< 1+ on dipstick or routine urinalysis (UA). If urine dipstick or routine analysis indicated proteinuria >= 2+, then a 24-hour urine is to be collected and demonstrate < 1000 mg of protein in 24 hours to allow participation in the study - Patients must not have a history of uncontrolled or poorly-controlled hypertension (defined as >= 150 / >= 90 mm Hg for > 4 weeks) despite standard medical management - International normalized ratio (INR) =< 1.5 (documented within 28 calendar days prior to randomization) - Partial thromboplastin time (PTT) =< 5 seconds above the institutional upper limit of normal (IULN) (unless receiving anticoagulation therapy) (documented within 28 calendar days prior to randomization) - Patients receiving warfarin must be switched to low molecular weight heparin and have achieved stable coagulation profile 14 days prior to randomization. If receiving warfarin, the patient must have an INR =< 3.0. For heparin and low molecular weight heparin (LMWH) there should be no active bleeding (that is, no bleeding within 14 days prior to first dose of protocol therapy) or pathological condition present that carries a high risk of bleeding (for example, tumor involving major vessels or known varices) - Patients must have Zubrod performance status 0-1 documented within 28 days prior to sub-study randomization - Pre-study history and physical exam must be obtained within 28 days prior to substudy randomization - Patients must not be pregnant or nursing. Women/men of reproductive potential must have agreed to use an effective contraceptive method during the study and 4 months after study completion. A woman is considered to be of "reproductive potential" if she has had menses at any time in the preceding 12 consecutive months. In addition to routine contraceptive methods, "effective contraception" also includes heterosexual celibacy and surgery intended to prevent pregnancy (or with a side-effect of pregnancy prevention) defined as a hysterectomy, bilateral oophorectomy or bilateral tubal ligation. However, if at any point a previously celibate patient chooses to become heterosexually active during the time period for use of contraceptive measures outlined in the protocol, he/she is responsible for beginning contraceptive measures during the study and 4 months after study completion - Patients must agree to have blood specimens submitted for circulating tumor DNA (ctDNA) - Patients must also be offered participation in banking and in the correlative studies for collection and future use of specimens - As a part of the Oncology Patient Enrollment Network (OPEN) registration process the treating institution's identity is provided in order to ensure that the current (within 365 days) date of institutional review board approval for this study has been entered in the system - Patients with impaired decision-making capacity are eligible as long as their neurological or psychological condition does not preclude their safe participation in the study (e.g., tracking pill consumption and reporting adverse events to the investigator) - Patients must be informed of the investigational nature of this study and must sign and give written informed consent in accordance with institutional and federal guidelines |
Country | Name | City | State |
---|---|---|---|
United States | Hawaii Cancer Care - Savio | 'Aiea | Hawaii |
United States | Pali Momi Medical Center | 'Aiea | Hawaii |
United States | Queen's Cancer Center - Pearlridge | 'Aiea | Hawaii |
United States | The Cancer Center of Hawaii-Pali Momi | 'Aiea | Hawaii |
United States | Providence Regional Cancer System-Aberdeen | Aberdeen | Washington |
United States | Riverwood Healthcare Center | Aitkin | Minnesota |
United States | Phoebe Putney Memorial Hospital | Albany | Georgia |
United States | New Mexico Oncology Hematology Consultants | Albuquerque | New Mexico |
United States | Presbyterian Kaseman Hospital | Albuquerque | New Mexico |
United States | University of New Mexico Cancer Center | Albuquerque | New Mexico |
United States | Lehigh Valley Hospital-Cedar Crest | Allentown | Pennsylvania |
United States | Aultman Alliance Community Hospital | Alliance | Ohio |
United States | The Don and Sybil Harrington Cancer Center | Amarillo | Texas |
United States | American Fork Hospital / Huntsman Intermountain Cancer Center | American Fork | Utah |
United States | Mary Greeley Medical Center | Ames | Iowa |
United States | McFarland Clinic PC - Ames | Ames | Iowa |
United States | Community Hospital of Anaconda | Anaconda | Montana |
United States | Kaiser Permanente-Anaheim | Anaheim | California |
United States | Alaska Breast Care and Surgery LLC | Anchorage | Alaska |
United States | Alaska Oncology and Hematology LLC | Anchorage | Alaska |
United States | Alaska Women's Cancer Care | Anchorage | Alaska |
United States | Anchorage Associates in Radiation Medicine | Anchorage | Alaska |
United States | Anchorage Oncology Centre | Anchorage | Alaska |
United States | Anchorage Radiation Therapy Center | Anchorage | Alaska |
United States | Katmai Oncology Group | Anchorage | Alaska |
United States | Providence Alaska Medical Center | Anchorage | Alaska |
United States | AnMed Health Cancer Center | Anderson | South Carolina |
United States | Saint Joseph Mercy Hospital | Ann Arbor | Michigan |
United States | Anne Arundel Medical Center | Annapolis | Maryland |
United States | Langlade Hospital and Cancer Center | Antigo | Wisconsin |
United States | PCR Oncology | Arroyo Grande | California |
United States | Randolph Hospital | Asheboro | North Carolina |
United States | Duluth Clinic Ashland | Ashland | Wisconsin |
United States | Northwest Wisconsin Cancer Center | Ashland | Wisconsin |
United States | University Cancer and Blood Center LLC | Athens | Georgia |
United States | Emory Saint Joseph's Hospital | Atlanta | Georgia |
United States | Emory University Hospital Midtown | Atlanta | Georgia |
United States | Emory University Hospital/Winship Cancer Institute | Atlanta | Georgia |
United States | Northside Hospital | Atlanta | Georgia |
United States | MultiCare Auburn Medical Center | Auburn | Washington |
United States | Sutter Auburn Faith Hospital | Auburn | California |
United States | Sutter Cancer Centers Radiation Oncology Services-Auburn | Auburn | California |
United States | Augusta University Medical Center | Augusta | Georgia |
United States | Harold Alfond Center for Cancer Care | Augusta | Maine |
United States | Rocky Mountain Cancer Centers-Aurora | Aurora | Colorado |
United States | Rush - Copley Medical Center | Aurora | Illinois |
United States | The Medical Center of Aurora | Aurora | Colorado |
United States | University of Colorado Hospital | Aurora | Colorado |
United States | Mount Sinai Comprehensive Cancer Center at Aventura | Aventura | Florida |
United States | Saint Alphonsus Medical Center-Baker City | Baker City | Oregon |
United States | Kaiser Permanente-Baldwin Park | Baldwin Park | California |
United States | Saint Louis Cancer and Breast Institute-Ballwin | Ballwin | Missouri |
United States | Saint Agnes Hospital | Baltimore | Maryland |
United States | Sinai Hospital of Baltimore | Baltimore | Maryland |
United States | Flaget Memorial Hospital | Bardstown | Kentucky |
United States | Medical Center of Baton Rouge | Baton Rouge | Louisiana |
United States | Ochsner High Grove | Baton Rouge | Louisiana |
United States | Bronson Battle Creek | Battle Creek | Michigan |
United States | UHHS-Chagrin Highlands Medical Center | Beachwood | Ohio |
United States | UPMC-Heritage Valley Health System Beaver | Beaver | Pennsylvania |
United States | Indu and Raj Soin Medical Center | Beavercreek | Ohio |
United States | Waldo County General Hospital | Belfast | Maine |
United States | Kaiser Permanente-Bellflower | Bellflower | California |
United States | PeaceHealth Saint Joseph Medical Center | Bellingham | Washington |
United States | Strecker Cancer Center-Belpre | Belpre | Ohio |
United States | Sanford Joe Lueken Cancer Center | Bemidji | Minnesota |
United States | Saint Charles Health System | Bend | Oregon |
United States | Alta Bates Summit Medical Center-Herrick Campus | Berkeley | California |
United States | Central Vermont Medical Center/National Life Cancer Treatment | Berlin | Vermont |
United States | Lehigh Valley Hospital - Muhlenberg | Bethlehem | Pennsylvania |
United States | University of Iowa Healthcare Cancer Services Quad Cities | Bettendorf | Iowa |
United States | Beverly Hospital | Beverly | Massachusetts |
United States | MaineHealth/SMHC Cancer Care and Blood Disorders-Biddeford | Biddeford | Maine |
United States | Billings Clinic Cancer Center | Billings | Montana |
United States | Saint Vincent Frontier Cancer Center | Billings | Montana |
United States | Saint Vincent Healthcare | Billings | Montana |
United States | Sanford Bismarck Medical Center | Bismarck | North Dakota |
United States | Illinois CancerCare-Bloomington | Bloomington | Illinois |
United States | Saint Elizabeth Boardman Hospital | Boardman | Ohio |
United States | Saint Alphonsus Cancer Care Center-Boise | Boise | Idaho |
United States | Saint Luke's Mountain States Tumor Institute | Boise | Idaho |
United States | Central Care Cancer Center - Bolivar | Bolivar | Missouri |
United States | Parkland Health Center-Bonne Terre | Bonne Terre | Missouri |
United States | McFarland Clinic PC-Boone | Boone | Iowa |
United States | Boulder Community Hospital | Boulder | Colorado |
United States | Rocky Mountain Cancer Centers-Boulder | Boulder | Colorado |
United States | Bozeman Deaconess Hospital | Bozeman | Montana |
United States | Essentia Health Saint Joseph's Medical Center | Brainerd | Minnesota |
United States | Cox Cancer Center Branson | Branson | Missouri |
United States | Northeast Georgia Medical Center Braselton | Braselton | Georgia |
United States | Harrison HealthPartners Hematology and Oncology-Bremerton | Bremerton | Washington |
United States | Harrison Medical Center | Bremerton | Washington |
United States | Lafayette Family Cancer Center-EMMC | Brewer | Maine |
United States | IHA Hematology Oncology Consultants-Brighton | Brighton | Michigan |
United States | Saint Joseph Mercy Brighton | Brighton | Michigan |
United States | James J Peters VA Medical Center | Bronx | New York |
United States | Henry Ford Cancer Institute-Downriver | Brownstown | Michigan |
United States | Saint Joseph Regional Cancer Center | Bryan | Texas |
United States | Bryn Mawr Hospital | Bryn Mawr | Pennsylvania |
United States | Roswell Park Cancer Institute | Buffalo | New York |
United States | Providence Saint Joseph Medical Center/Disney Family Cancer Center | Burbank | California |
United States | Highline Medical Center-Main Campus | Burien | Washington |
United States | Mills-Peninsula Medical Center | Burlingame | California |
United States | Aurora Cancer Care-Southern Lakes VLCC | Burlington | Wisconsin |
United States | Cone Health Cancer Center at Alamance Regional | Burlington | North Carolina |
United States | Lahey Hospital and Medical Center | Burlington | Massachusetts |
United States | University of Vermont and State Agricultural College | Burlington | Vermont |
United States | University of Vermont Medical Center | Burlington | Vermont |
United States | Fairview Ridges Hospital | Burnsville | Minnesota |
United States | Loyola Center for Health at Burr Ridge | Burr Ridge | Illinois |
United States | Saint James Community Hospital and Cancer Treatment Center | Butte | Montana |
United States | Saint Alphonsus Cancer Care Center-Caldwell | Caldwell | Idaho |
United States | Cambridge Medical Center | Cambridge | Minnesota |
United States | Sutter Cancer Centers Radiation Oncology Services-Cameron Park | Cameron Park | California |
United States | Aultman Health Foundation | Canton | Ohio |
United States | IHA Hematology Oncology Consultants-Canton | Canton | Michigan |
United States | Illinois CancerCare-Canton | Canton | Illinois |
United States | Mercy Medical Center | Canton | Ohio |
United States | Saint Joseph Mercy Canton | Canton | Michigan |
United States | Saint Francis Medical Center | Cape Girardeau | Missouri |
United States | Southeast Cancer Center | Cape Girardeau | Missouri |
United States | Memorial Hospital of Carbondale | Carbondale | Illinois |
United States | Caro Cancer Center | Caro | Michigan |
United States | Carson Tahoe Regional Medical Center | Carson City | Nevada |
United States | SIH Cancer Institute | Carterville | Illinois |
United States | Illinois CancerCare-Carthage | Carthage | Illinois |
United States | Eden Hospital Medical Center | Castro Valley | California |
United States | Sandra L Maxwell Cancer Center | Cedar City | Utah |
United States | Mercy Hospital | Cedar Rapids | Iowa |
United States | Oncology Associates at Mercy Medical Center | Cedar Rapids | Iowa |
United States | Dayton Physicians LLC-Miami Valley South | Centerville | Ohio |
United States | Miami Valley Hospital South | Centerville | Ohio |
United States | Centralia Oncology Clinic | Centralia | Illinois |
United States | Providence Regional Cancer System-Centralia | Centralia | Washington |
United States | Christiana Care Health System-Concord Health Center | Chadds Ford | Pennsylvania |
United States | Chambersburg Hospital | Chambersburg | Pennsylvania |
United States | Geauga Hospital | Chardon | Ohio |
United States | Novant Health Presbyterian Medical Center | Charlotte | North Carolina |
United States | University of Virginia Cancer Center | Charlottesville | Virginia |
United States | Memorial Hospital | Chattanooga | Tennessee |
United States | IHA Hematology Oncology Consultants-Chelsea | Chelsea | Michigan |
United States | Saint Joseph Mercy Chelsea | Chelsea | Michigan |
United States | Cheyenne Regional Medical Center-West | Cheyenne | Wyoming |
United States | Advocate Illinois Masonic Medical Center | Chicago | Illinois |
United States | John H Stroger Jr Hospital of Cook County | Chicago | Illinois |
United States | Northwestern University | Chicago | Illinois |
United States | Swedish Covenant Hospital | Chicago | Illinois |
United States | University of Chicago Comprehensive Cancer Center | Chicago | Illinois |
United States | Adena Regional Medical Center | Chillicothe | Ohio |
United States | Marshfield Clinic-Chippewa Center | Chippewa Falls | Wisconsin |
United States | Bethesda North Hospital | Cincinnati | Ohio |
United States | Good Samaritan Hospital - Cincinnati | Cincinnati | Ohio |
United States | Oncology Hematology Care Inc-Kenwood | Cincinnati | Ohio |
United States | TriHealth Cancer Institute-Anderson | Cincinnati | Ohio |
United States | TriHealth Cancer Institute-Westside | Cincinnati | Ohio |
United States | Clackamas Radiation Oncology Center | Clackamas | Oregon |
United States | Providence Cancer Institute Clackamas Clinic | Clackamas | Oregon |
United States | Hematology Oncology Consultants-Clarkston | Clarkston | Michigan |
United States | Newland Medical Associates-Clarkston | Clarkston | Michigan |
United States | Case Western Reserve University | Cleveland | Ohio |
United States | Cleveland Clinic Cancer Center/Fairview Hospital | Cleveland | Ohio |
United States | Cleveland Clinic Foundation | Cleveland | Ohio |
United States | Henry Ford Macomb Hospital-Clinton Township | Clinton Township | Michigan |
United States | Medical Oncology and Hematology Associates-West Des Moines | Clive | Iowa |
United States | Mercy Cancer Center-West Lakes | Clive | Iowa |
United States | Billings Clinic-Cody | Cody | Wyoming |
United States | Kootenai Medical Center | Coeur d'Alene | Idaho |
United States | Coffeyville Regional Medical Center | Coffeyville | Kansas |
United States | Main Line Health Center-Collegeville | Collegeville | Pennsylvania |
United States | Baptist Memorial Hospital and Cancer Center-Collierville | Collierville | Tennessee |
United States | Memorial Hospital North | Colorado Springs | Colorado |
United States | Penrose-Saint Francis Healthcare | Colorado Springs | Colorado |
United States | Rocky Mountain Cancer Centers-Penrose | Colorado Springs | Colorado |
United States | UCHealth Memorial Hospital Central | Colorado Springs | Colorado |
United States | Baptist Memorial Hospital and Cancer Center-Golden Triangle | Columbus | Mississippi |
United States | Columbus Oncology and Hematology Associates Inc | Columbus | Ohio |
United States | Doctors Hospital | Columbus | Ohio |
United States | Grant Medical Center | Columbus | Ohio |
United States | Mount Carmel East Hospital | Columbus | Ohio |
United States | Mount Carmel Health Center West | Columbus | Ohio |
United States | Riverside Methodist Hospital | Columbus | Ohio |
United States | The Mark H Zangmeister Center | Columbus | Ohio |
United States | New Hampshire Oncology Hematology PA-Concord | Concord | New Hampshire |
United States | Mercy Hospital | Coon Rapids | Minnesota |
United States | Mary Imogene Bassett Hospital | Cooperstown | New York |
United States | Bay Area Hospital | Coos Bay | Oregon |
United States | Commonwealth Cancer Center-Corbin | Corbin | Kentucky |
United States | Alegent Health Mercy Hospital | Council Bluffs | Iowa |
United States | Greater Regional Medical Center | Creston | Iowa |
United States | Western Maryland Regional Medical Center | Cumberland | Maryland |
United States | Parkland Memorial Hospital | Dallas | Texas |
United States | UT Southwestern/Simmons Cancer Center-Dallas | Dallas | Texas |
United States | Carle on Vermilion | Danville | Illinois |
United States | Genesis Cancer Care Institute | Davenport | Iowa |
United States | Genesis Medical Center - East Campus | Davenport | Iowa |
United States | Iowa Cancer Specialists | Davenport | Iowa |
United States | Sutter Davis Hospital | Davis | California |
United States | Dayton Physician LLC-Miami Valley Hospital North | Dayton | Ohio |
United States | Good Samaritan Hospital - Dayton | Dayton | Ohio |
United States | Miami Valley Hospital | Dayton | Ohio |
United States | Miami Valley Hospital North | Dayton | Ohio |
United States | Henry Ford Medical Center-Fairlane | Dearborn | Michigan |
United States | Atlanta VA Medical Center | Decatur | Georgia |
United States | Cancer Care Specialists of Illinois - Decatur | Decatur | Illinois |
United States | Decatur Memorial Hospital | Decatur | Illinois |
United States | Essentia Health - Deer River Clinic | Deer River | Minnesota |
United States | Delaware Health Center-Grady Cancer Center | Delaware | Ohio |
United States | Grady Memorial Hospital | Delaware | Ohio |
United States | Cancer Center of Colorado at Sloan's Lake | Denver | Colorado |
United States | Colorado Blood Cancer Institute | Denver | Colorado |
United States | National Jewish Health-Main Campus | Denver | Colorado |
United States | Porter Adventist Hospital | Denver | Colorado |
United States | Presbyterian - Saint Lukes Medical Center - Health One | Denver | Colorado |
United States | Rocky Mountain Cancer Centers-Midtown | Denver | Colorado |
United States | Rocky Mountain Cancer Centers-Rose | Denver | Colorado |
United States | Rose Medical Center | Denver | Colorado |
United States | SCL Health Saint Joseph Hospital | Denver | Colorado |
United States | The Women's Imaging Center | Denver | Colorado |
United States | Western Surgical Care | Denver | Colorado |
United States | Smilow Cancer Hospital-Derby Care Center | Derby | Connecticut |
United States | Medical Oncology and Hematology Associates-Laurel | Des Moines | Iowa |
United States | Mercy Medical Center - Des Moines | Des Moines | Iowa |
United States | Ascension Saint John Hospital | Detroit | Michigan |
United States | Henry Ford Hospital | Detroit | Michigan |
United States | Essentia Health Saint Mary's - Detroit Lakes Clinic | Detroit Lakes | Minnesota |
United States | Illinois CancerCare-Dixon | Dixon | Illinois |
United States | Bayhealth Hospital Kent Campus | Dover | Delaware |
United States | City of Hope Comprehensive Cancer Center | Duarte | California |
United States | Dublin Methodist Hospital | Dublin | Ohio |
United States | Essentia Health Cancer Center | Duluth | Minnesota |
United States | Essentia Health Saint Mary's Medical Center | Duluth | Minnesota |
United States | Miller-Dwan Hospital | Duluth | Minnesota |
United States | Northside Hospital - Duluth | Duluth | Georgia |
United States | Mercy Medical Center | Durango | Colorado |
United States | Southwest Oncology PC | Durango | Colorado |
United States | Duke University Medical Center | Durham | North Carolina |
United States | Durham VA Medical Center | Durham | North Carolina |
United States | Prisma Health Cancer Institute - Easley | Easley | South Carolina |
United States | Great Lakes Cancer Management Specialists-Doctors Park | East China Township | Michigan |
United States | Fox Chase Cancer Center - East Norriton Hospital Outpatient Center | East Norriton | Pennsylvania |
United States | Pocono Medical Center | East Stroudsburg | Pennsylvania |
United States | Marshfield Medical Center-EC Cancer Center | Eau Claire | Wisconsin |
United States | Fairview Southdale Hospital | Edina | Minnesota |
United States | Swedish Cancer Institute-Edmonds | Edmonds | Washington |
United States | Carle Physician Group-Effingham | Effingham | Illinois |
United States | Crossroads Cancer Center | Effingham | Illinois |
United States | Hardin Memorial Hospital | Elizabethtown | Kentucky |
United States | Arnot Ogden Medical Center/Falck Cancer Center | Elmira | New York |
United States | Mercy Cancer Center-Elyria | Elyria | Ohio |
United States | Walter Knox Memorial Hospital | Emmett | Idaho |
United States | Mountain Blue Cancer Care Center - Swedish | Englewood | Colorado |
United States | Swedish Medical Center | Englewood | Colorado |
United States | Saint Elizabeth Hospital | Enumclaw | Washington |
United States | Ephrata Cancer Center | Ephrata | Pennsylvania |
United States | Ephrata Community Hospital | Ephrata | Pennsylvania |
United States | UPMC Hamot | Erie | Pennsylvania |
United States | Green Bay Oncology - Escanaba | Escanaba | Michigan |
United States | Illinois CancerCare-Eureka | Eureka | Illinois |
United States | NorthShore University HealthSystem-Evanston Hospital | Evanston | Illinois |
United States | Providence Regional Cancer Partnership | Everett | Washington |
United States | Main Line Health Center-Exton | Exton | Pennsylvania |
United States | Fairbanks Memorial Hospital | Fairbanks | Alaska |
United States | Smilow Cancer Hospital Care Center-Fairfield | Fairfield | Connecticut |
United States | Essentia Health Cancer Center-South University Clinic | Fargo | North Dakota |
United States | Sanford Broadway Medical Center | Fargo | North Dakota |
United States | Sanford Medical Center Fargo | Fargo | North Dakota |
United States | Sanford Roger Maris Cancer Center | Fargo | North Dakota |
United States | Sanford South University Medical Center | Fargo | North Dakota |
United States | Southpointe-Sanford Medical Center Fargo | Fargo | North Dakota |
United States | Parkland Health Center - Farmington | Farmington | Missouri |
United States | Saint Francis Hospital | Federal Way | Washington |
United States | Lake Region Healthcare Corporation-Cancer Care | Fergus Falls | Minnesota |
United States | Armes Family Cancer Center | Findlay | Ohio |
United States | Blanchard Valley Hospital | Findlay | Ohio |
United States | Orion Cancer Care | Findlay | Ohio |
United States | Genesee Cancer and Blood Disease Treatment Center | Flint | Michigan |
United States | Genesee Hematology Oncology PC | Flint | Michigan |
United States | Genesys Hurley Cancer Institute | Flint | Michigan |
United States | Hurley Medical Center | Flint | Michigan |
United States | Aurora Health Center-Fond du Lac | Fond Du Lac | Wisconsin |
United States | Kaiser Permanente-Fontana | Fontana | California |
United States | Cancer Care and Hematology-Fort Collins | Fort Collins | Colorado |
United States | Poudre Valley Hospital | Fort Collins | Colorado |
United States | McFarland Clinic PC-Trinity Cancer Center | Fort Dodge | Iowa |
United States | Holy Cross Hospital | Fort Lauderdale | Florida |
United States | Mercy Hospital Fort Smith | Fort Smith | Arkansas |
United States | Parkview Regional Medical Center | Fort Wayne | Indiana |
United States | UT Southwestern/Simmons Cancer Center-Fort Worth | Fort Worth | Texas |
United States | Essentia Health - Fosston | Fosston | Minnesota |
United States | Atrium Medical Center-Middletown Regional Hospital | Franklin | Ohio |
United States | Dayton Physicians LLC-Atrium | Franklin | Ohio |
United States | Palo Alto Medical Foundation-Fremont | Fremont | California |
United States | Kaiser Permanente-Fresno | Fresno | California |
United States | Unity Hospital | Fridley | Minnesota |
United States | Saint Luke's Mountain States Tumor Institute - Fruitland | Fruitland | Idaho |
United States | Gibbs Cancer Center-Gaffney | Gaffney | South Carolina |
United States | Central Ohio Breast and Endocrine Surgery | Gahanna | Ohio |
United States | Northeast Georgia Medical Center-Gainesville | Gainesville | Georgia |
United States | Illinois CancerCare-Galesburg | Galesburg | Illinois |
United States | Western Illinois Cancer Treatment Center | Galesburg | Illinois |
United States | Central Care Cancer Center - Garden City | Garden City | Kansas |
United States | Aurora Health Care Germantown Health Center | Germantown | Wisconsin |
United States | Adams Cancer Center | Gettysburg | Pennsylvania |
United States | MultiCare Gig Harbor Medical Park | Gig Harbor | Washington |
United States | Glens Falls Hospital | Glens Falls | New York |
United States | NorthShore University HealthSystem-Glenbrook Hospital | Glenview | Illinois |
United States | Addison Gilbert Hospital | Gloucester | Massachusetts |
United States | Mountain Blue Cancer Care Center | Golden | Colorado |
United States | National Jewish Health-Western Hematology Oncology | Golden | Colorado |
United States | Goshen Center for Cancer Care | Goshen | Indiana |
United States | Aurora Cancer Care-Grafton | Grafton | Wisconsin |
United States | CHI Health Saint Francis | Grand Island | Nebraska |
United States | Saint Mary's Hospital and Regional Medical Center | Grand Junction | Colorado |
United States | Helen DeVos Children's Hospital at Spectrum Health | Grand Rapids | Michigan |
United States | Mercy Health Saint Mary's | Grand Rapids | Michigan |
United States | Spectrum Health at Butterworth Campus | Grand Rapids | Michigan |
United States | Central Care Cancer Center - Great Bend | Great Bend | Kansas |
United States | Benefis Healthcare- Sletten Cancer Institute | Great Falls | Montana |
United States | Great Falls Clinic | Great Falls | Montana |
United States | North Colorado Medical Center | Greeley | Colorado |
United States | UCHealth Greeley Hospital | Greeley | Colorado |
United States | Aurora BayCare Medical Center | Green Bay | Wisconsin |
United States | Saint Vincent Hospital Cancer Center at Saint Mary's | Green Bay | Wisconsin |
United States | Saint Vincent Hospital Cancer Center Green Bay | Green Bay | Wisconsin |
United States | Cone Health Cancer Center | Greensboro | North Carolina |
United States | UPMC Cancer Centers - Arnold Palmer Pavilion | Greensburg | Pennsylvania |
United States | Dayton Physicians LLC-Wayne | Greenville | Ohio |
United States | Prisma Health Cancer Institute - Butternut | Greenville | South Carolina |
United States | Prisma Health Cancer Institute - Eastside | Greenville | South Carolina |
United States | Prisma Health Cancer Institute - Faris | Greenville | South Carolina |
United States | Prisma Health Greenville Memorial Hospital | Greenville | South Carolina |
United States | Wayne Hospital | Greenville | Ohio |
United States | Gibbs Cancer Center-Pelham | Greer | South Carolina |
United States | Prisma Health Cancer Institute - Greer | Greer | South Carolina |
United States | Baptist Cancer Center-Grenada | Grenada | Mississippi |
United States | Academic Hematology Oncology Specialists | Grosse Pointe Woods | Michigan |
United States | Great Lakes Cancer Management Specialists-Van Elslander Cancer Center | Grosse Pointe Woods | Michigan |
United States | Michigan Breast Specialists-Grosse Pointe Woods | Grosse Pointe Woods | Michigan |
United States | Smilow Cancer Hospital Care Center - Guiford | Guilford | Connecticut |
United States | Gulfport Memorial Hospital | Gulfport | Mississippi |
United States | Cherry Tree Cancer Center | Hanover | Pennsylvania |
United States | Kaiser Permanente - Harbor City | Harbor City | California |
United States | UPMC Pinnacle Cancer Center/Community Osteopathic Campus | Harrisburg | Pennsylvania |
United States | Hartford Hospital | Hartford | Connecticut |
United States | Smilow Cancer Hospital Care Center at Saint Francis | Hartford | Connecticut |
United States | HaysMed University of Kansas Health System | Hays | Kansas |
United States | Lehigh Valley Hospital-Hazleton | Hazleton | Pennsylvania |
United States | Saint Peter's Community Hospital | Helena | Montana |
United States | 21st Century Oncology-Henderson | Henderson | Nevada |
United States | Cancer and Blood Specialists-Henderson | Henderson | Nevada |
United States | Comprehensive Cancer Centers of Nevada - Henderson | Henderson | Nevada |
United States | Comprehensive Cancer Centers of Nevada-Horizon Ridge | Henderson | Nevada |
United States | Comprehensive Cancer Centers of Nevada-Southeast Henderson | Henderson | Nevada |
United States | Las Vegas Cancer Center-Henderson | Henderson | Nevada |
United States | Las Vegas Urology - Pebble | Henderson | Nevada |
United States | OptumCare Cancer Care at Seven Hills | Henderson | Nevada |
United States | Margaret R Pardee Memorial Hospital | Hendersonville | North Carolina |
United States | Essentia Health Hibbing Clinic | Hibbing | Minnesota |
United States | NorthShore University HealthSystem-Highland Park Hospital | Highland Park | Illinois |
United States | UCHealth Highlands Ranch Hospital | Highlands Ranch | Colorado |
United States | Edward Hines Jr VA Hospital | Hines | Illinois |
United States | Pulmonary Medicine Center of Chattanooga-Hixson | Hixson | Tennessee |
United States | Memorial Regional Hospital/Joe DiMaggio Children's Hospital | Hollywood | Florida |
United States | Hawaii Cancer Care Inc-Liliha | Honolulu | Hawaii |
United States | Hawaii Cancer Care Inc-POB II | Honolulu | Hawaii |
United States | Island Urology | Honolulu | Hawaii |
United States | Kapiolani Medical Center for Women and Children | Honolulu | Hawaii |
United States | Kuakini Medical Center | Honolulu | Hawaii |
United States | Queen's Cancer Cenrer - POB I | Honolulu | Hawaii |
United States | Queen's Cancer Center - Kuakini | Honolulu | Hawaii |
United States | Queen's Medical Center | Honolulu | Hawaii |
United States | Straub Clinic and Hospital | Honolulu | Hawaii |
United States | The Cancer Center of Hawaii-Liliha | Honolulu | Hawaii |
United States | University of Hawaii Cancer Center | Honolulu | Hawaii |
United States | CHI Saint Vincent Cancer Center Hot Springs | Hot Springs | Arkansas |
United States | Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center | Houston | Texas |
United States | Ben Taub General Hospital | Houston | Texas |
United States | M D Anderson Cancer Center | Houston | Texas |
United States | Edwards Comprehensive Cancer Center | Huntington | West Virginia |
United States | Saint Mary's Medical Center | Huntington | West Virginia |
United States | Centerpoint Medical Center LLC | Independence | Missouri |
United States | Franciscan Health Indianapolis | Indianapolis | Indiana |
United States | University of Iowa/Holden Comprehensive Cancer Center | Iowa City | Iowa |
United States | Kaiser Permanente-Irvine | Irvine | California |
United States | Swedish Cancer Institute-Issaquah | Issaquah | Washington |
United States | Allegiance Health | Jackson | Michigan |
United States | University of Mississippi Medical Center | Jackson | Mississippi |
United States | Essentia Health - Jamestown Clinic | Jamestown | North Dakota |
United States | McFarland Clinic PC-Jefferson | Jefferson | Iowa |
United States | Capital Region Southwest Campus | Jefferson City | Missouri |
United States | Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro | Jonesboro | Arkansas |
United States | Freeman Health System | Joplin | Missouri |
United States | Mercy Hospital Joplin | Joplin | Missouri |
United States | Borgess Medical Center | Kalamazoo | Michigan |
United States | Bronson Methodist Hospital | Kalamazoo | Michigan |
United States | West Michigan Cancer Center | Kalamazoo | Michigan |
United States | Kalispell Regional Medical Center | Kalispell | Montana |
United States | Research Medical Center | Kansas City | Missouri |
United States | Saint Luke's Hospital of Kansas City | Kansas City | Missouri |
United States | The University of Kansas Cancer Center-South | Kansas City | Missouri |
United States | Truman Medical Centers | Kansas City | Missouri |
United States | University of Kansas Cancer Center | Kansas City | Kansas |
United States | University of Kansas Cancer Center - North | Kansas City | Missouri |
United States | University of Kansas Cancer Center-West | Kansas City | Kansas |
United States | CHI Health Good Samaritan | Kearney | Nebraska |
United States | Heartland Hematology and Oncology | Kearney | Nebraska |
United States | Ochsner Medical Center Kenner | Kenner | Louisiana |
United States | Kadlec Clinic Hematology and Oncology | Kennewick | Washington |
United States | Aurora Cancer Care-Kenosha South | Kenosha | Wisconsin |
United States | Novant Health Oncology Specialists-Kernersville | Kernersville | North Carolina |
United States | First Dayton Cancer Care | Kettering | Ohio |
United States | Greater Dayton Cancer Center | Kettering | Ohio |
United States | Kettering Medical Center | Kettering | Ohio |
United States | Illinois CancerCare-Kewanee Clinic | Kewanee | Illinois |
United States | Kingman Regional Medical Center | Kingman | Arizona |
United States | Seattle Cancer Care Alliance at EvergreenHealth | Kirkland | Washington |
United States | Gundersen Lutheran Medical Center | La Crosse | Wisconsin |
United States | UC San Diego Moores Cancer Center | La Jolla | California |
United States | Providence Regional Cancer System-Lacey | Lacey | Washington |
United States | Marshfield Clinic - Ladysmith Center | Ladysmith | Wisconsin |
United States | Good Samaritan Medical Center | Lafayette | Colorado |
United States | Northwestern Medicine Lake Forest Hospital | Lake Forest | Illinois |
United States | Rocky Mountain Cancer Centers-Lakewood | Lakewood | Colorado |
United States | Saint Anthony Hospital | Lakewood | Colorado |
United States | Saint Clare Hospital | Lakewood | Washington |
United States | Fairfield Medical Center | Lancaster | Ohio |
United States | Sparrow Hospital | Lansing | Michigan |
United States | Memorial Medical Center - Las Cruces | Las Cruces | New Mexico |
United States | 21st Century Oncology | Las Vegas | Nevada |
United States | 21st Century Oncology-Fort Apache | Las Vegas | Nevada |
United States | 21st Century Oncology-Vegas Tenaya | Las Vegas | Nevada |
United States | Alliance for Childhood Diseases/Cure 4 the Kids Foundation | Las Vegas | Nevada |
United States | Ann M Wierman MD LTD | Las Vegas | Nevada |
United States | Cancer and Blood Specialists-Shadow | Las Vegas | Nevada |
United States | Cancer and Blood Specialists-Tenaya | Las Vegas | Nevada |
United States | Comprehensive Cancer Centers of Nevada | Las Vegas | Nevada |
United States | Comprehensive Cancer Centers of Nevada - Central Valley | Las Vegas | Nevada |
United States | Comprehensive Cancer Centers of Nevada - Northwest | Las Vegas | Nevada |
United States | Comprehensive Cancer Centers of Nevada - Town Center | Las Vegas | Nevada |
United States | Comprehensive Cancer Centers of Nevada-Summerlin | Las Vegas | Nevada |
United States | Desert West Surgery | Las Vegas | Nevada |
United States | HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills | Las Vegas | Nevada |
United States | HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway | Las Vegas | Nevada |
United States | HealthCare Partners Medical Group Oncology/Hematology-San Martin | Las Vegas | Nevada |
United States | HealthCare Partners Medical Group Oncology/Hematology-Tenaya | Las Vegas | Nevada |
United States | Hope Cancer Care of Nevada | Las Vegas | Nevada |
United States | Las Vegas Cancer Center-Medical Center | Las Vegas | Nevada |
United States | Las Vegas Urology - Cathedral Rock | Las Vegas | Nevada |
United States | Las Vegas Urology - Pecos | Las Vegas | Nevada |
United States | Las Vegas Urology - Smoke Ranch | Las Vegas | Nevada |
United States | OptumCare Cancer Care at Fort Apache | Las Vegas | Nevada |
United States | OptumCare Cancer Care at MountainView | Las Vegas | Nevada |
United States | OptumCare Cancer Care at Oakey | Las Vegas | Nevada |
United States | Radiation Oncology Centers of Nevada Central | Las Vegas | Nevada |
United States | Radiation Oncology Centers of Nevada Southeast | Las Vegas | Nevada |
United States | Summerlin Hospital Medical Center | Las Vegas | Nevada |
United States | Sunrise Hospital and Medical Center | Las Vegas | Nevada |
United States | University Cancer Center | Las Vegas | Nevada |
United States | University Medical Center of Southern Nevada | Las Vegas | Nevada |
United States | Northside Hospital - Gwinnett | Lawrenceville | Georgia |
United States | Cancer Centers of Southwest Oklahoma Research | Lawton | Oklahoma |
United States | Dartmouth Hitchcock Medical Center | Lebanon | New Hampshire |
United States | Sechler Family Cancer Center | Lebanon | Pennsylvania |
United States | Saint Luke's East - Lee's Summit | Lee's Summit | Missouri |
United States | University of Kansas Cancer Center - Lee's Summit | Lee's Summit | Missouri |
United States | Kansas Institute of Medicine Cancer and Blood Center | Lenexa | Kansas |
United States | Minimally Invasive Surgery Hospital | Lenexa | Kansas |
United States | Beebe Medical Center | Lewes | Delaware |
United States | Saint Joseph Hospital East | Lexington | Kentucky |
United States | Saint Joseph Radiation Oncology Resource Center | Lexington | Kentucky |
United States | University of Kentucky/Markey Cancer Center | Lexington | Kentucky |
United States | Wilcox Memorial Hospital and Kauai Medical Clinic | Lihue | Hawaii |
United States | Saint Elizabeth Regional Medical Center | Lincoln | Nebraska |
United States | University of Arkansas for Medical Sciences | Little Rock | Arkansas |
United States | Littleton Adventist Hospital | Littleton | Colorado |
United States | Rocky Mountain Cancer Centers-Littleton | Littleton | Colorado |
United States | Hope Cancer Clinic | Livonia | Michigan |
United States | Saint Mary Mercy Hospital | Livonia | Michigan |
United States | Logan Regional Hospital | Logan | Utah |
United States | Loma Linda University Medical Center | Loma Linda | California |
United States | Veterans Affairs Loma Linda Healthcare System | Loma Linda | California |
United States | Saint Joseph London | London | Kentucky |
United States | Rocky Mountain Cancer Centers-Sky Ridge | Lone Tree | Colorado |
United States | Sky Ridge Medical Center | Lone Tree | Colorado |
United States | UCHealth Lone Tree Health Center | Lone Tree | Colorado |
United States | Tibor Rubin VA Medical Center | Long Beach | California |
United States | Monmouth Medical Center | Long Branch | New Jersey |
United States | Longmont United Hospital | Longmont | Colorado |
United States | Rocky Mountain Cancer Centers-Longmont | Longmont | Colorado |
United States | PeaceHealth Saint John Medical Center | Longview | Washington |
United States | Kaiser Permanente Los Angeles Medical Center | Los Angeles | California |
United States | Kaiser Permanente-Cadillac | Los Angeles | California |
United States | Jewish Hospital | Louisville | Kentucky |
United States | Jewish Hospital Medical Center Northeast | Louisville | Kentucky |
United States | Saints Mary and Elizabeth Hospital | Louisville | Kentucky |
United States | McKee Medical Center | Loveland | Colorado |
United States | Medical Center of the Rockies | Loveland | Colorado |
United States | Lowell General Hospital | Lowell | Massachusetts |
United States | Centra Lynchburg Hematology-Oncology Clinic Inc | Lynchburg | Virginia |
United States | Great Lakes Cancer Management Specialists-Macomb Medical Campus | Macomb | Michigan |
United States | Illinois CancerCare-Macomb | Macomb | Illinois |
United States | Michigan Breast Specialists-Macomb Township | Macomb | Michigan |
United States | Norris Cotton Cancer Center-Manchester | Manchester | New Hampshire |
United States | Solinsky Center for Cancer Care | Manchester | New Hampshire |
United States | Holy Family Memorial Hospital | Manitowoc | Wisconsin |
United States | Cleveland Clinic Cancer Center Mansfield | Mansfield | Ohio |
United States | OhioHealth Mansfield Hospital | Mansfield | Ohio |
United States | Fairview Clinics and Surgery Center Maple Grove | Maple Grove | Minnesota |
United States | Minnesota Oncology Hematology PA-Maplewood | Maplewood | Minnesota |
United States | Saint John's Hospital - Healtheast | Maplewood | Minnesota |
United States | Marietta Memorial Hospital | Marietta | Ohio |
United States | Aurora Bay Area Medical Group-Marinette | Marinette | Wisconsin |
United States | Saint Vincent Hospital Cancer Center at Marinette | Marinette | Wisconsin |
United States | OhioHealth Marion General Hospital | Marion | Ohio |
United States | Saint Mary's Oncology/Hematology Associates of Marlette | Marlette | Michigan |
United States | McFarland Clinic PC-Marshalltown | Marshalltown | Iowa |
United States | Marshfield Medical Center-Marshfield | Marshfield | Wisconsin |
United States | Fremont - Rideout Cancer Center | Marysville | California |
United States | Novant Health Cancer Specialists-Matthews | Matthews | North Carolina |
United States | Carle Physician Group-Mattoon/Charleston | Mattoon | Illinois |
United States | Hillcrest Hospital Cancer Center | Mayfield Heights | Ohio |
United States | UH Seidman Cancer Center at Landerbrook Health Center | Mayfield Heights | Ohio |
United States | Loyola University Medical Center | Maywood | Illinois |
United States | UPMC Cancer Center at UPMC McKeesport | McKeesport | Pennsylvania |
United States | Cone Heath Cancer Center at Mebane | Mebane | North Carolina |
United States | Bon Secours Memorial Regional Medical Center | Mechanicsville | Virginia |
United States | Aspirus Medford Hospital | Medford | Wisconsin |
United States | Riddle Memorial Hospital | Media | Pennsylvania |
United States | Marjorie Weinberg Cancer Center at Loyola-Gottlieb | Melrose Park | Illinois |
United States | Baptist Memorial Hospital and Cancer Center-Memphis | Memphis | Tennessee |
United States | Froedtert Menomonee Falls Hospital | Menomonee Falls | Wisconsin |
United States | UH Seidman Cancer Center at Lake Health Mentor Campus | Mentor | Ohio |
United States | Idaho Urologic Institute-Meridian | Meridian | Idaho |
United States | Saint Luke's Mountain States Tumor Institute - Meridian | Meridian | Idaho |
United States | Mount Sinai Medical Center | Miami Beach | Florida |
United States | Woodland Cancer Care Center | Michigan City | Indiana |
United States | UH Seidman Cancer Center at Southwest General Hospital | Middleburg Heights | Ohio |
United States | Bon Secours Saint Francis Medical Center | Midlothian | Virginia |
United States | Bayhealth Hospital Sussex Campus | Milford | Delaware |
United States | Aurora Cancer Care-Milwaukee | Milwaukee | Wisconsin |
United States | Aurora Saint Luke's Medical Center | Milwaukee | Wisconsin |
United States | Aurora Sinai Medical Center | Milwaukee | Wisconsin |
United States | Medical College of Wisconsin | Milwaukee | Wisconsin |
United States | Abbott-Northwestern Hospital | Minneapolis | Minnesota |
United States | Health Partners Inc | Minneapolis | Minnesota |
United States | Hennepin County Medical Center | Minneapolis | Minnesota |
United States | Minneapolis VA Medical Center | Minneapolis | Minnesota |
United States | Marshfield Clinic-Minocqua Center | Minocqua | Wisconsin |
United States | Community Medical Hospital | Missoula | Montana |
United States | Saint Patrick Hospital - Community Hospital | Missoula | Montana |
United States | University of South Alabama Mitchell Cancer Institute | Mobile | Alabama |
United States | Memorial Medical Center | Modesto | California |
United States | UPMC Cancer Center - Monroeville | Monroeville | Pennsylvania |
United States | Monticello Cancer Center | Monticello | Minnesota |
United States | Virtua Samson Cancer Center | Moorestown | New Jersey |
United States | Franciscan Health Mooresville | Mooresville | Indiana |
United States | Saint Claire Regional Medical Center | Morehead | Kentucky |
United States | Novant Health Oncology Specialists-Mount Airy | Mount Airy | North Carolina |
United States | Good Samaritan Regional Health Center | Mount Vernon | Illinois |
United States | Knox Community Hospital | Mount Vernon | Ohio |
United States | Palo Alto Medical Foundation-Camino Division | Mountain View | California |
United States | Palo Alto Medical Foundation-Gynecologic Oncology | Mountain View | California |
United States | Intermountain Medical Center | Murray | Utah |
United States | Mercy Health Mercy Campus | Muskegon | Michigan |
United States | Saint Alphonsus Medical Center-Nampa | Nampa | Idaho |
United States | Saint Luke's Mountain States Tumor Institute - Nampa | Nampa | Idaho |
United States | Norris Cotton Cancer Center-Nashua | Nashua | New Hampshire |
United States | Baptist Memorial Hospital and Cancer Center-Union County | New Albany | Mississippi |
United States | The Hospital of Central Connecticut | New Britain | Connecticut |
United States | Smilow Cancer Center/Yale-New Haven Hospital | New Haven | Connecticut |
United States | Yale University | New Haven | Connecticut |
United States | UC Comprehensive Cancer Center at Silver Cross | New Lenox | Illinois |
United States | Louisiana State University Health Science Center | New Orleans | Louisiana |
United States | Ochsner Medical Center Jefferson | New Orleans | Louisiana |
United States | University Medical Center New Orleans | New Orleans | Louisiana |
United States | Cancer Center of Western Wisconsin | New Richmond | Wisconsin |
United States | New Ulm Medical Center | New Ulm | Minnesota |
United States | Mount Sinai Chelsea | New York | New York |
United States | Mount Sinai Hospital | New York | New York |
United States | Christiana Care Health System-Christiana Hospital | Newark | Delaware |
United States | Delaware Clinical and Laboratory Physicians PA | Newark | Delaware |
United States | Helen F Graham Cancer Center | Newark | Delaware |
United States | Licking Memorial Hospital | Newark | Ohio |
United States | Medical Oncology Hematology Consultants PA | Newark | Delaware |
United States | Newark Radiation Oncology | Newark | Ohio |
United States | Providence Newberg Medical Center | Newberg | Oregon |
United States | Bryn Mawr Health Center | Newtown Square | Pennsylvania |
United States | Lakeland Hospital Niles | Niles | Michigan |
United States | Bon Secours DePaul Medical Center | Norfolk | Virginia |
United States | Yale-New Haven Hospital North Haven Medical Center | North Haven | Connecticut |
United States | University of Kansas Cancer Center at North Kansas City Hospital | North Kansas City | Missouri |
United States | Cancer and Hematology Centers of Western Michigan - Norton Shores | Norton Shores | Michigan |
United States | Sutter Cancer Research Consortium | Novato | California |
United States | Henry Ford Medical Center-Columbus | Novi | Michigan |
United States | Cancer Care Center of O'Fallon | O'Fallon | Illinois |
United States | Kaiser Permanente-Oakland | Oakland | California |
United States | Saint Vincent Hospital Cancer Center at Oconto Falls | Oconto Falls | Wisconsin |
United States | McKay-Dee Hospital Center | Ogden | Utah |
United States | Mercy Hospital Oklahoma City | Oklahoma City | Oklahoma |
United States | University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma |
United States | Olathe Health Cancer Center | Olathe | Kansas |
United States | Alegent Health Bergan Mercy Medical Center | Omaha | Nebraska |
United States | Alegent Health Immanuel Medical Center | Omaha | Nebraska |
United States | Alegent Health Lakeside Hospital | Omaha | Nebraska |
United States | Creighton University Medical Center | Omaha | Nebraska |
United States | Hematology and Oncology Consultants PC | Omaha | Nebraska |
United States | Saint Alphonsus Medical Center-Ontario | Ontario | Oregon |
United States | Memorial GYN Plus | Ooltewah | Tennessee |
United States | Saint Joseph Hospital - Orange | Orange | California |
United States | Smilow Cancer Hospital-Orange Care Center | Orange | Connecticut |
United States | Loyola Center for Cancer Care and Research | Orland Park | Illinois |
United States | University of Chicago Medicine-Orland Park | Orland Park | Illinois |
United States | Vince Lombardi Cancer Clinic - Oshkosh | Oshkosh | Wisconsin |
United States | Illinois CancerCare-Ottawa Clinic | Ottawa | Illinois |
United States | Menorah Medical Center | Overland Park | Kansas |
United States | Saint Luke's South Hospital | Overland Park | Kansas |
United States | University of Kansas Cancer Center-Overland Park | Overland Park | Kansas |
United States | Owensboro Health Mitchell Memorial Cancer Center | Owensboro | Kentucky |
United States | Baptist Memorial Hospital and Cancer Center-Oxford | Oxford | Mississippi |
United States | Hope Cancer Care of Nevada-Pahrump | Pahrump | Nevada |
United States | Palo Alto Medical Foundation Health Care | Palo Alto | California |
United States | Stanford Cancer Institute Palo Alto | Palo Alto | California |
United States | Kaiser Permanente - Panorama City | Panorama City | California |
United States | Paoli Memorial Hospital | Paoli | Pennsylvania |
United States | Midlands Community Hospital | Papillion | Nebraska |
United States | Essentia Health - Park Rapids | Park Rapids | Minnesota |
United States | Parker Adventist Hospital | Parker | Colorado |
United States | Rocky Mountain Cancer Centers-Parker | Parker | Colorado |
United States | University Hospitals Parma Medical Center | Parma | Ohio |
United States | Illinois CancerCare-Pekin | Pekin | Illinois |
United States | Memorial Hospital West | Pembroke Pines | Florida |
United States | Illinois CancerCare-Peoria | Peoria | Illinois |
United States | Methodist Medical Center of Illinois | Peoria | Illinois |
United States | Illinois CancerCare-Peru | Peru | Illinois |
United States | Valley Radiation Oncology | Peru | Illinois |
United States | Fox Chase Cancer Center | Philadelphia | Pennsylvania |
United States | Temple University Hospital | Philadelphia | Pennsylvania |
United States | Thomas Jefferson University Hospital | Philadelphia | Pennsylvania |
United States | FirstHealth of the Carolinas-Moore Regional Hospital | Pinehurst | North Carolina |
United States | Ascension Via Christi - Pittsburg | Pittsburg | Kansas |
United States | University of Pittsburgh Cancer Institute (UPCI) | Pittsburgh | Pennsylvania |
United States | UPMC-Passavant Hospital | Pittsburgh | Pennsylvania |
United States | UPMC-Saint Clair Hospital Cancer Center | Pittsburgh | Pennsylvania |
United States | UPMC-Saint Margaret | Pittsburgh | Pennsylvania |
United States | 21st Century Oncology-Pontiac | Pontiac | Michigan |
United States | Hope Cancer Center | Pontiac | Michigan |
United States | Newland Medical Associates-Pontiac | Pontiac | Michigan |
United States | Saint Joseph Mercy Oakland | Pontiac | Michigan |
United States | Huron Medical Center PC | Port Huron | Michigan |
United States | Lake Huron Medical Center | Port Huron | Michigan |
United States | Jefferson Healthcare | Port Townsend | Washington |
United States | Kaiser Permanente Northwest | Portland | Oregon |
United States | Oregon Health and Science University | Portland | Oregon |
United States | Providence Portland Medical Center | Portland | Oregon |
United States | Providence Saint Vincent Medical Center | Portland | Oregon |
United States | Bon Secours Maryview Medical Center | Portsmouth | Virginia |
United States | Southern Ohio Medical Center | Portsmouth | Ohio |
United States | Kootenai Cancer Center | Post Falls | Idaho |
United States | Pottstown Hospital | Pottstown | Pennsylvania |
United States | Harrison HealthPartners Hematology and Oncology-Poulsbo | Poulsbo | Washington |
United States | Fairview Northland Medical Center | Princeton | Minnesota |
United States | Illinois CancerCare-Princeton | Princeton | Illinois |
United States | Utah Valley Regional Medical Center | Provo | Utah |
United States | Rocky Mountain Cancer Centers - Pueblo | Pueblo | Colorado |
United States | Saint Mary Corwin Medical Center | Pueblo | Colorado |
United States | MultiCare Good Samaritan Hospital | Puyallup | Washington |
United States | Aurora Cancer Care-Racine | Racine | Wisconsin |
United States | Duke Raleigh Hospital | Raleigh | North Carolina |
United States | Eisenhower Medical Center | Rancho Mirage | California |
United States | Northwest Hospital Center | Randallstown | Maryland |
United States | Rapid City Regional Hospital | Rapid City | South Dakota |
United States | University Hospitals Portage Medical Center | Ravenna | Ohio |
United States | Saint Charles Health System-Redmond | Redmond | Oregon |
United States | Spectrum Health Reed City Hospital | Reed City | Michigan |
United States | Beebe Health Campus | Rehoboth Beach | Delaware |
United States | Annie Penn Memorial Hospital | Reidsville | North Carolina |
United States | Radiation Oncology Associates | Reno | Nevada |
United States | Renown Regional Medical Center | Reno | Nevada |
United States | Saint Mary's Regional Medical Center | Reno | Nevada |
United States | Valley Medical Center | Renton | Washington |
United States | Marshfield Medical Center-Rice Lake | Rice Lake | Wisconsin |
United States | UT Southwestern Clinical Center at Richardson/Plano | Richardson | Texas |
United States | Bon Secours Cancer Institute at Reynolds Crossing | Richmond | Virginia |
United States | Bon Secours Saint Mary's Hospital | Richmond | Virginia |
United States | Reid Health | Richmond | Indiana |
United States | VCU Massey Cancer Center at Stony Point | Richmond | Virginia |
United States | Virginia Cancer Institute | Richmond | Virginia |
United States | Virginia Commonwealth University/Massey Cancer Center | Richmond | Virginia |
United States | Presbyterian Rust Medical Center/Jorgensen Cancer Center | Rio Rancho | New Mexico |
United States | Kaiser Permanente-Riverside | Riverside | California |
United States | Riverton Hospital | Riverton | Utah |
United States | North Memorial Medical Health Center | Robbinsdale | Minnesota |
United States | University of Rochester | Rochester | New York |
United States | Great Lakes Cancer Management Specialists-Rochester Hills | Rochester Hills | Michigan |
United States | OSF Saint Anthony Medical Center | Rockford | Illinois |
United States | Penobscot Bay Medical Center | Rockport | Maine |
United States | Delbert Day Cancer Institute at PCRMC | Rolla | Missouri |
United States | Mercy Clinic-Rolla-Cancer and Hematology | Rolla | Missouri |
United States | Kaiser Permanente-Roseville | Roseville | California |
United States | Sutter Cancer Centers Radiation Oncology Services-Roseville | Roseville | California |
United States | Sutter Roseville Medical Center | Roseville | California |
United States | Kaiser Permanente Downtown Commons | Sacramento | California |
United States | Sutter Medical Center Sacramento | Sacramento | California |
United States | University of California Davis Comprehensive Cancer Center | Sacramento | California |
United States | Ascension Saint Mary's Hospital | Saginaw | Michigan |
United States | Oncology Hematology Associates of Saginaw Valley PC | Saginaw | Michigan |
United States | Dixie Medical Center Regional Cancer Center | Saint George | Utah |
United States | Heartland Regional Medical Center | Saint Joseph | Missouri |
United States | Lakeland Medical Center Saint Joseph | Saint Joseph | Michigan |
United States | Marie Yeager Cancer Center | Saint Joseph | Michigan |
United States | Mercy Hospital Saint Louis | Saint Louis | Missouri |
United States | Mercy Hospital South | Saint Louis | Missouri |
United States | Missouri Baptist Medical Center | Saint Louis | Missouri |
United States | Saint Louis Cancer and Breast Institute-South City | Saint Louis | Missouri |
United States | Park Nicollet Clinic - Saint Louis Park | Saint Louis Park | Minnesota |
United States | Regions Hospital | Saint Paul | Minnesota |
United States | United Hospital | Saint Paul | Minnesota |
United States | Sainte Genevieve County Memorial Hospital | Sainte Genevieve | Missouri |
United States | Salem Hospital | Salem | Oregon |
United States | Salina Regional Health Center | Salina | Kansas |
United States | LDS Hospital | Salt Lake City | Utah |
United States | Utah Cancer Specialists-Salt Lake City | Salt Lake City | Utah |
United States | Kaiser Permanente-San Diego Mission | San Diego | California |
United States | Kaiser Permanente-San Diego Zion | San Diego | California |
United States | California Pacific Medical Center-Pacific Campus | San Francisco | California |
United States | Kaiser Permanente-San Francisco | San Francisco | California |
United States | Kaiser Permanente-Santa Teresa-San Jose | San Jose | California |
United States | Kaiser Permanente San Leandro | San Leandro | California |
United States | Kaiser Permanente-San Marcos | San Marcos | California |
United States | Kaiser San Rafael-Gallinas | San Rafael | California |
United States | Kootenai Cancer Clinic | Sandpoint | Idaho |
United States | Essentia Health Sandstone | Sandstone | Minnesota |
United States | North Coast Cancer Care | Sandusky | Ohio |
United States | UH Seidman Cancer Center at Firelands Regional Medical Center | Sandusky | Ohio |
United States | MaineHealth/SMHC Cancer Care and Blood Disorders-Sanford | Sanford | Maine |
United States | Kaiser Permanente Medical Center - Santa Clara | Santa Clara | California |
United States | Palo Alto Medical Foundation-Santa Cruz | Santa Cruz | California |
United States | Sutter Pacific Medical Foundation | Santa Rosa | California |
United States | Lewis Cancer and Research Pavilion at Saint Joseph's/Candler | Savannah | Georgia |
United States | Guthrie Medical Group PC-Robert Packer Hospital | Sayre | Pennsylvania |
United States | Maine Medical Center- Scarborough Campus | Scarborough | Maine |
United States | Nanticoke Memorial Hospital | Seaford | Delaware |
United States | Fred Hutchinson Cancer Research Center | Seattle | Washington |
United States | Kaiser Permanente Washington | Seattle | Washington |
United States | Pacific Gynecology Specialists | Seattle | Washington |
United States | Seattle Cancer Care Alliance | Seattle | Washington |
United States | Seattle Cancer Care Alliance at Northwest Hospital | Seattle | Washington |
United States | Swedish Medical Center-Ballard Campus | Seattle | Washington |
United States | Swedish Medical Center-Cherry Hill | Seattle | Washington |
United States | Swedish Medical Center-First Hill | Seattle | Washington |
United States | University of Washington Medical Center | Seattle | Washington |
United States | PeaceHealth United General Medical Center | Sedro-Woolley | Washington |
United States | Prisma Health Cancer Institute - Seneca | Seneca | South Carolina |
United States | Saint Francis Regional Medical Center | Shakopee | Minnesota |
United States | HSHS Saint Nicholas Hospital | Sheboygan | Wisconsin |
United States | Vince Lombardi Cancer Clinic-Sheboygan | Sheboygan | Wisconsin |
United States | Providence Regional Cancer System-Shelton | Shelton | Washington |
United States | Jewish Hospital Medical Center South | Shepherdsville | Kentucky |
United States | Welch Cancer Center | Sheridan | Wyoming |
United States | Genesis Cancer Center - Silvis | Silvis | Illinois |
United States | Siouxland Regional Cancer Center | Sioux City | Iowa |
United States | Sanford Cancer Center Oncology Clinic | Sioux Falls | South Dakota |
United States | Sanford USD Medical Center - Sioux Falls | Sioux Falls | South Dakota |
United States | Suburban Hematology Oncology Associates - Snellville | Snellville | Georgia |
United States | Robert Wood Johnson University Hospital Somerset | Somerville | New Jersey |
United States | Memorial Hospital of South Bend | South Bend | Indiana |
United States | VCU Community Memorial Health Center | South Hill | Virginia |
United States | City of Hope South Pasadena | South Pasadena | California |
United States | Maine Medical Partners - South Portland | South Portland | Maine |
United States | Kaiser Permanente-South San Francisco | South San Francisco | California |
United States | Baptist Memorial Hospital and Cancer Center-Desoto | Southhaven | Mississippi |
United States | Prisma Health Cancer Institute - Spartanburg | Spartanburg | South Carolina |
United States | Spartanburg Medical Center | Spartanburg | South Carolina |
United States | MultiCare Deaconess Cancer and Blood Specialty Center - Downtown | Spokane | Washington |
United States | MultiCare Deaconess Cancer and Blood Specialty Center - North | Spokane | Washington |
United States | MultiCare Deaconess Cancer and Blood Specialty Center - Valley | Spokane Valley | Washington |
United States | Baystate Medical Center | Springfield | Massachusetts |
United States | CoxHealth South Hospital | Springfield | Missouri |
United States | Memorial Medical Center | Springfield | Illinois |
United States | Mercy Hospital Springfield | Springfield | Missouri |
United States | Mercy Medical Center | Springfield | Massachusetts |
United States | Southern Illinois University School of Medicine | Springfield | Illinois |
United States | Springfield Clinic | Springfield | Illinois |
United States | Springfield Regional Cancer Center | Springfield | Ohio |
United States | Springfield Regional Medical Center | Springfield | Ohio |
United States | Novant Health Oncology Specialists-Statesville | Statesville | North Carolina |
United States | Bhadresh Nayak MD PC-Sterling Heights | Sterling Heights | Michigan |
United States | Marshfield Clinic Stevens Point Center | Stevens Point | Wisconsin |
United States | Lakeview Hospital | Stillwater | Minnesota |
United States | Cleveland Clinic Cancer Center Strongsville | Strongsville | Ohio |
United States | Saint Vincent Hospital Cancer Center at Sturgeon Bay | Sturgeon Bay | Wisconsin |
United States | Bon Secours Health Center at Harbour View | Suffolk | Virginia |
United States | Missouri Baptist Sullivan Hospital | Sullivan | Missouri |
United States | Aurora Medical Center in Summit | Summit | Wisconsin |
United States | Palo Alto Medical Foundation-Sunnyvale | Sunnyvale | California |
United States | Missouri Baptist Outpatient Center-Sunset Hills | Sunset Hills | Missouri |
United States | Southwest Illinois Health Services LLP | Swansea | Illinois |
United States | ProMedica Flower Hospital | Sylvania | Ohio |
United States | Franciscan Research Center-Northwest Medical Plaza | Tacoma | Washington |
United States | Mary Bridge Children's Hospital and Health Center | Tacoma | Washington |
United States | MultiCare Tacoma General Hospital | Tacoma | Washington |
United States | Moffitt Cancer Center | Tampa | Florida |
United States | Ascension Saint Joseph Hospital | Tawas City | Michigan |
United States | Union Hospital | Terre Haute | Indiana |
United States | Sanford Thief River Falls Medical Center | Thief River Falls | Minnesota |
United States | Novant Health Oncology Specialists-Davidson County | Thomasville | North Carolina |
United States | National Jewish Health-Northern Hematology Oncology | Thornton | Colorado |
United States | Rocky Mountain Cancer Centers-Thornton | Thornton | Colorado |
United States | ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital | Toledo | Ohio |
United States | Cotton O'Neil Cancer Center / Stormont Vail Health | Topeka | Kansas |
United States | University of Kansas Health System Saint Francis Campus | Topeka | Kansas |
United States | Smilow Cancer Hospital-Torrington Care Center | Torrington | Connecticut |
United States | Munson Medical Center | Traverse City | Michigan |
United States | Dayton Physicians LLC-Upper Valley | Troy | Ohio |
United States | Upper Valley Medical Center | Troy | Ohio |
United States | Gene Upshaw Memorial Tahoe Forest Cancer Center | Truckee | California |
United States | Smilow Cancer Hospital Care Center-Trumbull | Trumbull | Connecticut |
United States | Oklahoma Cancer Specialists and Research Institute-Tulsa | Tulsa | Oklahoma |
United States | Saint Luke's Mountain States Tumor Institute-Twin Falls | Twin Falls | Idaho |
United States | Vince Lombardi Cancer Clinic-Two Rivers | Two Rivers | Wisconsin |
United States | MGC Hematology Oncology-Union | Union | South Carolina |
United States | Carle Cancer Center | Urbana | Illinois |
United States | The Carle Foundation Hospital | Urbana | Illinois |
United States | Northbay Cancer Center | Vacaville | California |
United States | Sutter Cancer Centers Radiation Oncology Services-Vacaville | Vacaville | California |
United States | Kaiser Permanente-Vallejo | Vallejo | California |
United States | Sutter Solano Medical Center/Cancer Center | Vallejo | California |
United States | PeaceHealth Southwest Medical Center | Vancouver | Washington |
United States | Essentia Health Virginia Clinic | Virginia | Minnesota |
United States | Virtua Voorhees | Voorhees | New Jersey |
United States | Ridgeview Medical Center | Waconia | Minnesota |
United States | University Hospitals Sharon Health Center | Wadsworth | Ohio |
United States | Providence Saint Mary Regional Cancer Center | Walla Walla | Washington |
United States | Kaiser Permanente-Walnut Creek | Walnut Creek | California |
United States | Advanced Breast Care Center PLLC | Warren | Michigan |
United States | Great Lakes Cancer Management Specialists-Macomb Professional Building | Warren | Michigan |
United States | Macomb Hematology Oncology PC | Warren | Michigan |
United States | Michigan Breast Specialists-Warren | Warren | Michigan |
United States | Saint John Macomb-Oakland Hospital | Warren | Michigan |
United States | Saint Joseph Warren Hospital | Warren | Ohio |
United States | South Pointe Hospital | Warrensville Heights | Ohio |
United States | Mercy Hospital Washington | Washington | Missouri |
United States | UPMC Washington Hospital Radiation Oncology | Washington | Pennsylvania |
United States | Smilow Cancer Hospital-Waterbury Care Center | Waterbury | Connecticut |
United States | Smilow Cancer Hospital Care Center - Waterford | Waterford | Connecticut |
United States | Aspirus Regional Cancer Center | Wausau | Wisconsin |
United States | Marshfield Clinic-Wausau Center | Wausau | Wisconsin |
United States | Aurora Cancer Care-Milwaukee West | Wauwatosa | Wisconsin |
United States | Aurora West Allis Medical Center | West Allis | Wisconsin |
United States | Froedtert West Bend Hospital/Kraemer Cancer Center | West Bend | Wisconsin |
United States | Henry Ford West Bloomfield Hospital | West Bloomfield | Michigan |
United States | Saint Mary's Oncology/Hematology Associates of West Branch | West Branch | Michigan |
United States | Mercy Medical Center-West Lakes | West Des Moines | Iowa |
United States | Veterans Affairs Connecticut Healthcare System-West Haven Campus | West Haven | Connecticut |
United States | Saint Ann's Hospital | Westerville | Ohio |
United States | UH Seidman Cancer Center at Saint John Medical Center | Westlake | Ohio |
United States | UHHS-Westlake Medical Center | Westlake | Ohio |
United States | William E Kahlert Regional Cancer Center/Sinai Hospital | Westminster | Maryland |
United States | Cleveland Clinic-Weston | Weston | Florida |
United States | Marshfield Clinic - Weston Center | Weston | Wisconsin |
United States | University of Kansas Hospital-Westwood Cancer Center | Westwood | Kansas |
United States | SCL Health Lutheran Medical Center | Wheat Ridge | Colorado |
United States | White River Junction Veteran Administration Medical Center | White River Junction | Vermont |
United States | Presbyterian Intercommunity Hospital | Whittier | California |
United States | Novant Health Oncology Specialists-Wilkesboro | Wilkesboro | North Carolina |
United States | UPMC Susquehanna | Williamsport | Pennsylvania |
United States | Rice Memorial Hospital | Willmar | Minnesota |
United States | Christiana Care Health System-Wilmington Hospital | Wilmington | Delaware |
United States | Shenandoah Oncology PC | Winchester | Virginia |
United States | Novant Health Forsyth Medical Center | Winston-Salem | North Carolina |
United States | Novant Health Oncology Specialists | Winston-Salem | North Carolina |
United States | Aspirus UW Cancer Center | Wisconsin Rapids | Wisconsin |
United States | Marshfield Clinic - Wisconsin Rapids Center | Wisconsin Rapids | Wisconsin |
United States | Minnesota Oncology Hematology PA-Woodbury | Woodbury | Minnesota |
United States | Kaiser Permanente-Woodland Hills | Woodland Hills | California |
United States | Cleveland Clinic Wooster Family Health and Surgery Center | Wooster | Ohio |
United States | UMass Memorial Medical Center - University Campus | Worcester | Massachusetts |
United States | Sanford Cancer Center Worthington | Worthington | Minnesota |
United States | Lankenau Medical Center | Wynnewood | Pennsylvania |
United States | Fairview Lakes Medical Center | Wyoming | Minnesota |
United States | Metro Health Hospital | Wyoming | Michigan |
United States | Providence Regional Cancer System-Yelm | Yelm | Washington |
United States | WellSpan Health-York Cancer Center | York | Pennsylvania |
United States | WellSpan Health-York Hospital | York | Pennsylvania |
United States | Rush-Copley Healthcare Center | Yorkville | Illinois |
United States | Saint Elizabeth Youngstown Hospital | Youngstown | Ohio |
United States | Huron Gastroenterology PC | Ypsilanti | Michigan |
United States | IHA Hematology Oncology Consultants-Ann Arbor | Ypsilanti | Michigan |
United States | Genesis Healthcare System Cancer Care Center | Zanesville | Ohio |
Lead Sponsor | Collaborator |
---|---|
SWOG Cancer Research Network | National Cancer Institute (NCI) |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Overall Survival (OS) | Time from date of registration to date of death due to any cause. Participants last known to be alive are censored at date of last contact. | From date of registration to a maximum of 2 years and 11 months or death | |
Secondary | Response Rate (RR) | Percentage of participants with a complete or partial, confirmed or unconfirmed response.
Complete Response (CR): Complete disappearance of all target and non-target lesions. No new lesions. No disease related symptoms. Any lymph nodes (whether target or non-target) must have reduction in short axis to < 1.0 cm. All disease must be assessed using the same technique as baseline. Partial Response (PR): Applies only to participants with at least one measurable lesion. Greater than or equal to 30% decrease under baseline of the sum of appropriate diameters of all target measurable lesions. No unequivocal progression of non-measurable disease. No new lesions. All target measurable lesions must be assessed using the same techniques as baseline. |
From date of registration to a maximum of 3 years or death | |
Secondary | Disease Control Rate (DCR) | Percentage of participants with complete response (CR), partial response (PR), or stable disease as best response.
CR: Complete disappearance of all target and non-target lesions. No new lesions. No disease related symptoms. Any lymph nodes must have reduction in short axis to <1.0cm. All disease must be assessed using the same technique as baseline. PR: Applies only to participants with at least one measurable lesion. At least 30% decrease under baseline of the sum of appropriate diameters of all target measurable lesions. No unequivocal progression of non-measurable disease. No new lesions. All target measurable lesions must be assessed using the same techniques as baseline. Stable disease: Does not qualify for CR, PR, Progression or Symptomatic Deterioration. All target measurable lesions must be assessed using the same techniques as baseline. |
From date of registration to a maximum of 3 years or death | |
Secondary | Duration of Response (DOR) | Time from date of first documentation of response (complete or partial) to date of first documentation of progression assessed by local review or symptomatic deterioration, or death due to any cause among participants who achieve a response. Participants last known to be alive without report of progression are censored at date of last disease assessment. For participants with a missing scan (or consecutive missing scans) whose subsequent scan determines progression, the expected date of the first missing scan (as defined by the disease assessment schedule) is used as the date of progression. | From date of registration to a maximum of 3 years or death | |
Secondary | Number of Participants With Gr 3 Through 5 Adverse Events That Are Related to Study Drugs | Only adverse events that are possibly, probably or definitely related to study drugs are reported. CTCAE Version 5.0 was used for all AE reporting. | Duration of treatment and follow-up until death or 3 years post randomization | |
Secondary | Investigator Assessed-progression-free Survival (IA-PFS) | Time from date of registration to date of first documentation of progression assessed by local review or symptomatic deterioration, or death due to any cause. Participants last known to be alive without report of progression are censored at date of last disease assessment. For participants with a missing scan (or consecutive missing scans) whose subsequent scan determines progression, the expected date of the first missing scan is used as the date of progression.
Symptomatic deterioration: Global deterioration of health status requiring discontinuation of treatment without objective evidence of progression. Efforts should be made to obtain objective evidence of progression after discontinuation. |
From date of registration to a maximum of 3 years or death | |
Secondary | Overall Survival (OS), Subgroup Analysis by Stratification Factors | Number of participants who died due to any cause. Participants last known to be alive are censored at date of last contact. | From date of registration to a maximum of 3 years or death | |
Secondary | Investigator-Assessed Progression-Free Survival (IA-PFS), Subgroup Analysis by Stratification Factors | Number of participants with progression assessed by local review or symptomatic deterioration, or death due to any cause. Participants last known to be alive without report of progression are censored at date of last disease assessment. For participants with a missing scan (or consecutive missing scans) whose subsequent scan determines progression, the expected date of the first missing scan is used as the date of progression.
Symptomatic deterioration: Global deterioration of health status requiring discontinuation of treatment without objective evidence of progression. Efforts should be made to obtain objective evidence of progression after discontinuation. |
From date of registration to a maximum of 3 years or death |
Status | Clinical Trial | Phase | |
---|---|---|---|
Withdrawn |
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