Refractory Multiple Myeloma Clinical Trial
Official title:
A Phase II Trial of Sunitinib (SU11248) in Multiple Myeloma
This phase II trial is studying how well sunitinib works in treating patients with relapsed multiple myeloma. Sunitinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the cancer
PRIMARY OBJECTIVES:
I. To assess the number of responses in patients with relapsed multiple myeloma treated with
sunitinib (sunitinib malate).
SECONDARY OBJECTIVES:
I. To assess the toxicity of sunitinib malate in patients with relapsed multiple myeloma.
II. To assess time to progression after initial response to sunitinib malate.
OUTLINE:
Patients receive oral sunitinib malate once daily on days 1-42. Treatment repeats every 42
days for up to 12 courses in the absence of disease progression or unacceptable toxicity.
After completion of study treatment, patients are followed every 3-6 months for up to 3
years.
;
Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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