Stage IB1 Cervical Cancer Clinical Trial
Official title:
Feasibility Study: Conservative Treatment in Cervical Cancer FIGO Stage IB1-IIA1 > 2cm
Currently conservative treatment for patients of childbearing affected by cervical cancer is
reserved for women with FIGO stage IA2 - IB1 with tumor size less than 2 cm . The
trachelectomy and the cone biopsy with pelvic lymphadenectomy are the choice for these
patients wishing to preserve their reproductive function.
In this context , recently literature show the results about the use of neo-adjuvant
chemotherapy about the reduction of tumor volume and therefore the magnitude of the
subsequent surgical treatment (including patients with tumors larger than 2 cm ). So it
becomes crucial a prospective analysis on the possibility to include in this type of
treatment patients with stage IB1 and IIA1 with tumor size greater than 2 cm ( up to 4 cm )
.
The current study , in fact , would like to do a prospective evaluation on the advantages of
neo-adjuvant chemotherapy in the possibility of broadening the inclusion criteria to
conservative treatment in women , suffering from cervical cancer, stage IB1 and IIA1 ( with
tumor volume between 2 and 4 cm) and wishing to preserve their reproductive function.
The investigators would like to be conservative in young patients affected by early stage cervical cancer. ;
Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Active, not recruiting |
NCT04219904 -
PET/MRI Scan for the Evaluation of Resectable Stage IA1-IB3 Cervical Cancer
|
Early Phase 1 |