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Stable Chronic Angina clinical trials

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NCT ID: NCT06075602 Recruiting - Clinical trials for Coronary Artery Disease

COMPLEX Registry - A Prospective COhort Study to Describe the Management and Outcomes of Patients Presenting With compLEX and Calcified Coronary Artery Disease

COMPLEX
Start date: November 1, 2021
Phase:
Study type: Observational [Patient Registry]

The purpose of the COMPLEX Registry is to prospectively and retrospectively collect baseline, clinical and procedural data of patients who have undergone PCI or CABG for complex and/ or calcified chronic CAD, irrespective of clinical presentation as well as to prospectively collect data about their clinical outcomes. The outcomes will be compared in different clinical subgroups (e.g. PCI vs. CABG). The impact of current PCI techniques/ devices, but also CABG strategies in different clinical settings and coronary artery lesions on cardiovascular outcomes will be assessed.

NCT ID: NCT04988685 Recruiting - Clinical trials for Coronary Artery Disease

SIROOP Registry - A Prospective Registry Study to Evaluate the Outcomes of Coronary Artery Disease Patients Treated With SIROlimus Or Paclitaxel Eluting Balloon Catheters

SIROOP
Start date: June 1, 2021
Phase:
Study type: Observational [Patient Registry]

The purpose of the SIROOP Registry is to retrospectively and prospectively collect baseline, clinical and procedural characteristics of patients who have undergone PCI and are treated with either currently available sirolimus or paclitaxel coated DCBs (see Table 1), irrespective of clinical presentation as well as to prospectively collect data about their clinical outcomes. Outcomes will be compared in different clinical subgroups. The impact of current DCBs in different clinical settings and coronary artery lesions on cardiovascular outcomes will be assessed.

NCT ID: NCT04144881 Recruiting - Clinical trials for Coronary Artery Disease

Angiographic Control vs. Ischemia-driven Management of Patients Treated With PCI on Left Main With Drug-eluting Stents

PULSE
Start date: October 15, 2019
Phase: N/A
Study type: Interventional

The present study aims to compare a planned angiographic control (PAC) follow-up strategy vs. conservative management for patients treated with drug-eluting stents on unprotected left main artery in a prospective, randomized setting. PAC will be performed by coronary computed tomography (CCT), to avoid the limitations of the invasive coronary angiography which is usually employed to perform PAC. The superiority of a PAC-based approach will be tested on a hard clinical end-point such as the incidence of major adverse cardiovascular events. The investigators will also assess the performance of CCT as a tool to perform PAC.

NCT ID: NCT03911895 Recruiting - Clinical trials for Stable Chronic Angina

Impact of Stent Length on Short Term Outcomes in Patients With Stable Coronary Disease Undergoing PCI

Start date: July 1, 2019
Phase:
Study type: Observational

Impact of stent length on short term outcomes in patients with stable coronary artery disease undergoing PCI

NCT ID: NCT03075124 Recruiting - Clinical trials for Coronary Artery Disease

Effect of External Counter Pulsation on Coronary Artery Disease

ECP-CAD
Start date: June 8, 2018
Phase: Phase 3
Study type: Interventional

Coronary artery disease (CAD) is prevalent worldwide and the leading cause of mortality of citizens, external counter pulsation (ECP) has been elucidated that it may release angina symptoms and improve the prognosis of CAD, however, no multi-center control clinical study has been reported for further recommendation. The aim of this study is to evaluate the effect of ECP on CAD. To address this assumption, investigators enroll participants with stable CAD and randomize them into control or ECP group, the ECP intervention will be carried out with a standard protocol which involves 35 one-hour sessions (5 days a week) for continuous 7 weeks, and the follow-up will last for 1 year. The primary endpoint is the 1-year composite cardiovascular events (CCE), secondary endpoints include frequency of angina pectoris, heart function, biomarkers of arteriosclerosis, exercise tolerance and endothelial function.