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NCT00719992 Clinical Trial

Diagnostic Value of HS-CRP in Stable Angina.

Stable Angina Clinical Trial

Official title:
Diagnostic Value of HS-CRP in Stable Angina Patients With Positive Exercise Test as Compared With Coronary Angiography.

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00719992
Other study ID # 4543
Secondary ID
Status Completed
Phase N/A
First received July 18, 2008
Last updated July 18, 2008
Start date April 2006
Est. completion date August 2007

Study information
Verified date July 2008
Source Shiraz University of Medical Sciences
Contact n/a
Is FDA regulated No
Health authority Iran: Ministry of Health
Study type Interventional

Clinical Trial Summary

The aim of this study was to assess the amount of additive value of HS-CRP levels to a positive exercise tolerance test (ETT) in predicting coronary artery disease (CAD) using coronary angiography as the gold standard. The investigators concluded that HS-CRP can be used as a single predictor of coronary vessel involvement in patients with stable angina and positive ETT.

Description:

the investigators included 97 patients with positive ETT and stable angina and saw that Hs-CRP is the only predictor of severity of CAD as compared with coronary angiography in stable angina patients.

Recruitment information / eligibility
Status Completed
Enrollment 97
Est. completion date August 2007
Est. primary completion date August 2007
Accepts healthy volunteers No
Gender Both
Age group 43 Years to 64 Years
Eligibility Inclusion Criteria:

- Stable angina

- Positive ETT

Exclusion Criteria:

- Unability to perform ETT

- Contraindications for ETT and angiography study

Study Design

Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Diagnostic

Related Conditions & MeSH terms

Intervention

Procedure:
• coronary angiography
effect of level of HS-CRP

Locations
Country Name City State
Iran, Islamic Republic of Cardiology Ward Shiraz University of Medical Sciences Shiraz Fars

Sponsors (1)
Lead Sponsor Collaborator
Shiraz University of Medical Sciences

Country where clinical trial is conducted

Iran, Islamic Republic of, 

Outcome
Type Measure Description Time frame Safety issue
Primary significant coronary lesion No
Secondary severity of CAD No
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