Impact of Long Distance Mountain Race on Knee Cartilage.

Sports Medicine Clinical Trial

— UT4M2020  

Official title:

Assessment of the Impact of an Ultratrail on the Knee Cartilage by Using T2 MRI: a Pilot Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04545216
• Other study ID #: UT4M 2020 - 38RC20.008
• Status: Completed
• Start date: September 3, 2020
• Est. completion date: December 31, 2021

Study information

• Verified date: March 2022
• Source: University Hospital, Grenoble
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Long-distance mountain running is increasingly popular among European and North America countries. Long-distance races are organized in various mountains and can reach up to 160 km (100 miles) with several thousands meters of climbing. The pathophysiological consequences of such extreme effort is still a matter a debate. From a muskelo-skeletal perspectives, the potential lower-limb join damage is a major health issue. The present study aims to use objective magnetic resonance imaging (MRI) techniques to describe the consequences of performing long-distance mountain running races on the knee cartilage.

Description:

Healthy male runners will perform T2 MRI knee cartilage examination before, immediatly after and 1 month after 3 distinct long-distance mountain races of 40, 55 and 160 km. The physiological responses during the races (speed, heart rate, glycemia) will also be recordered.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 54
• Est. completion date: December 31, 2021
• Est. primary completion date: August 31, 2021
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 18 Years to 60 Years

Eligibility

Inclusion Criteria:

• no cardiac, respiratory or neuromuscular diseases
• more than 2 years of experience in mountain race
• no contre-indication for participating in a mountain race

Exclusion Criteria:

• history of knee surgery
• contre-indication to MRI

Related Conditions & MeSH terms

• Sports Medicine

Intervention

Other:
• Long-distance mountain running
Impact of a mountain race on the knee cartilage

Locations

Country	Name	City	State
France	Doutreleau	Grenoble

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital, Grenoble

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	T2 MRI	Change in T2 relaxation time of the knee cartilage	from before to immediatly after the long-distance race
Secondary	Heart rate	Mean heart rate during the race	Continuous measurement during the race
Secondary	Glycemia	Mean glycemia during the race	Continuous measurement during the race