Heavy Metals' Influence on Early Pregnancy Through Oxidative Stress

Status Recruiting

Clinical Trial Summary

Patients with diagnosis of spontaneous abortion are enrolled in the cohort, in the cohort of patients who met the criteria, 3ml of whole blood intravenous and 5ml of urine were taken for heavy metal level examnation. Part of the villi tissue was sent for genetic testing, and the results were traced. In addition, about 10g of villi tissue was frozen for testing. Patients with normal genetic results of villi tissue will have villus samples go through oxidative stress level detection.

Clinical Trial Description

From May 1, 2019, patients with diagnosis of spontaneous abortion are enrolled in the cohort, exclusion criteria were: not long-term residents in Peking; Inconvenient for following up; Long-term of drug use; Cesarean section scar pregnancy and other high-risk pregnancy; Diagnosis of pregnancy beyond 12 weeks.

In the cohort of patients who met the criteria, 3ml of whole blood intravenous and 5ml of urine were taken on the day of admission for curettage and suction, and the levels of heavy metals were tested. Part of the villi tissue was sent for genetic testing, and the results were traced. In addition, about 10g of villi tissue was frozen for testing. Patients with normal genetic results of villi tissue will have villus samples go through oxidative stress level detection. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04003064
Study type	Observational [Patient Registry]
Source	Peking Union Medical College Hospital
Contact	Xinyan U Liu
Phone	01069156699
Email	cristinaO@163.com
Status	Recruiting
Phase
Start date	May 20, 2019
Completion date	May 1, 2020

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