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Clinical Trial Summary

Opioid overdose suppresses brainstem respiratory circuits, causes apnea, and may result in death. Epidural electrical stimulation (EES) at the cervical spinal cord facilitated motor activity in rodents and humans, and we hypothesized that EES of the cervical spinal cord could antagonize opioid-induced respiratory depression in humans. In this study, we will stimulate the spinal cord during surgery and assess its effects on respiratory function in human patients.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05356286
Study type Interventional
Source University of California, Los Angeles
Contact Daniel Lu, MD
Phone 310/825/4321
Email dclu@mednet.ucla.edu
Status Recruiting
Phase N/A
Start date January 21, 2011
Completion date January 22, 2027

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