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Spondyloarthropathy clinical trials

View clinical trials related to Spondyloarthropathy.

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NCT ID: NCT06252064 Completed - Spondyloarthropathy Clinical Trials

Rehabilitative Therapy and Pridinol in Patients With Lumbar Spondylarthrosis and Chronic Low Back Pain

Start date: March 1, 2022
Phase: N/A
Study type: Interventional

Spondyloarthrosis is a degenerative disease involving the intervertebral disc, vertebral bodies, and adjacent soft tissues. Treatment aims to slow disease progression and manage symptoms through an interdisciplinary approach.It can be conservative, pharmacological and interventional, rarely chirurgic. This study aimed to evaluate the effectiveness of a rehabilitation program combined with Pridinol Mesylate in the treatment of Spondyloarthrosis in elderly patients in terms of pain resolution, improving disability, and quality of life versus single treatment. A randomized controlled trial was conducted in patients with spondyloarthritis. The patients recruited were divided into three groups: the Combined Group (CG), who received a rehabilitation program combined with Pridinol Mesylate; the Rehabilitation Group (RG), who received only the same rehabilitation program; and the Drug Group (DG), who received only the administration of the drug.

NCT ID: NCT05431283 Recruiting - Ulcerative Colitis Clinical Trials

Real-world Effectiveness of Tofacitinib on Ulcerative Colitis Associated Spondyloarthropathy

RETUCAS
Start date: April 25, 2022
Phase:
Study type: Observational

Tofacitinib (TOFA) is a JAK inhibitor already used in rheumatology for the treatment of moderate-to-severe active rheumatoid arthritis and psoriatic arthritis in adult patients who have responded inadequately to, or who are intolerant to one or more disease- modifying antirheumatic drugs. Furthermore, TOFA has been recently approved for the treatment of adult patients with moderate-to-severe active Ulcerative Colitis (UC) who had no response, lose response, or were intolerant to either conventional therapy or a biologic agent. The approval was based on the efficacy demonstrated by TOFA in three phase 3 randomized controlled trials named OCTAVE: two identically designed, 8-week, placebo- controlled, induction studies of oral TOFA 10 mg twice daily followed by the OCTAVE Sustain 52-week maintenance study. About sacroiliitis, 2 out of 8 patients treated with TOFA improved after 8 weeks, compared with 0 out of 3 patients in the placebo group. Obviously, these data should be interpreted with extreme caution since patient numbers were very low, and it should be again emphasized that these trials were not designed to explore the efficacy of TOFA onextraintestinal manifestations. On these premises, we designed a prospective, multicenter, observational, 52-week study with the aim of assess the effectiveness of TOFA on UC-associated spondyloarthropathy.

NCT ID: NCT04673825 Completed - Psoriatic Arthritis Clinical Trials

Monitoring Spondyloarthritis With SpA-Net

TeleSpA
Start date: December 2, 2020
Phase: N/A
Study type: Interventional

Randomized controlled trial to assess the effectiveness and cost-effectiveness of an intervention combining patient initiated care and telemonitoring through the online eHealth platform SpA-Net versus standard care for patients with spondyloarthritis.

NCT ID: NCT03459274 Recruiting - Clinical trials for Rheumatoid Arthritis

Feasibility of an Immersive Virtual Reality Based Biofeedback Intervention for Outpatients in Rheumatology

Start date: March 16, 2018
Phase:
Study type: Observational

The purpose is to study the use of virtual reality (VR) and biofeedback in rheumatology clinics to help manage chronic pain in patients with rheumatologic diseases. The objective is to know the usefulness of VR/biofeedback-based therapy in the clinic.

NCT ID: NCT03287596 Completed - Tendinopathy Clinical Trials

Cartography and Quantitative Characterization of Achilles Tendon Fibrocartilage by TE = 0ms Imaging at 3T MRI

SILENZ
Start date: April 7, 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to accurately map calcaneal fibrocartilage using TE = 0 ms imaging, and then apply measurements of our control population to SpA patients with peripheral enthesis study using the calcaneal tendon as a clinical model

NCT ID: NCT03064815 Completed - Crohn Disease Clinical Trials

The SpACE Study - Small Bowel Crohn's Disease and Spondyloarthropathies

SpACE
Start date: June 2009
Phase: N/A
Study type: Interventional

Inflammatory bowel disease is clinically associated with spondylarthropathies in 5-15% of cases. Protocol colonoscopic assessment demonstrated asymptomatic inflammation characteristic of Crohn's disease in up to 1/3 of SpA patients. Videocapsule endoscopy is a superior diagnostic tool to detect small bowel mucosal pathology. However, it has been infrequently used to evaluate bowel inflammation in spondylarthropathies. This study compared the accuracy of videocapsule endoscopy to standard ileocolonoscopy for the detection of inflammatory bowel lesions in patients with spondylarthropathies, and to describe the clinical and laboratory predictors of small bowel inflammation in this cohort.

NCT ID: NCT02960035 Completed - Spondyloarthropathy Clinical Trials

A Study of the MASEI in the Treatment of Anti-TNF Blocker to Peripheral Tendonitis in Patients With Spondyloarthritis

Start date: April 2014
Phase: Phase 4
Study type: Interventional

This is a randomized, double-blind, multicentral clinical trial to investigate the efficacy of Recombinant Human Tumor Necrosis Factor-α Receptor Ⅱ IgG Fc fusion protein injection (Yisaipu®) in the treatment of peripheral enthesitis in active axial spondyloarthritis(SpA) patients.

NCT ID: NCT02948608 Active, not recruiting - Spondyloarthropathy Clinical Trials

Clinical Characteristics of Importance to Outcome in Patients With Spondyloarthritis

Start date: March 1, 2017
Phase:
Study type: Observational

The objective of the study is to investigate extra-articular manifestations, pain mechanisms, patient-reported outcomes, comorbidities and association between these conditions in patients with spondyloarthropathy (SpA) treated with Biologics. Further, to assess the predictive value of baseline pain profile on treatment outcome after ≥ 3 months.

NCT ID: NCT01718951 Completed - Spondyloarthropathy Clinical Trials

Golimumab Versus Pamidronate for the Treatment of Axial Spondyloarthropathy: a 48-week Trial

Start date: August 2012
Phase: Phase 4
Study type: Interventional

To compare the efficacy of golimumab with pamidronate in the treatment of axial spondyloarthropathy

NCT ID: NCT00383617 Completed - Clinical trials for Ankylosing Spondylitis

Referral Recommendations for Axial Spondyloarthritis

Start date: July 2004
Phase: N/A
Study type: Observational

The purpose of this study is to determine which of the proposed screening parameters or which combination of screening parameters perform best in daily clinical practice for making the diagnosis of axial Spondyloarthritis (SpA)in patients with chronic low back pain.