Clinical Trials Logo

Clinical Trial Summary

24 adults, between the ages of 18 and 75 years, with cerebellar ataxia will be enrolled in a 12 week trial of BHV-4157 for treatment of ataxia. BHV-4157 is a pro-drug of riluzole (which is currently FDA-approved for ALS, Lou Gehrig's disease). There will be 5 visits to UCLA required--Screening when general and neurological examination, blood and urine testing, ECG, and questionnaires will be administered; Baseline when general and neurological examination and questionnaires will be administered and study drug dispensed; Week 4 and Week 12 when general and neurological examination, blood and urine testing, ECG, and questionnaires will be administered; 2 weeks after finishing study drug when general examination and blood testing will be completed. There is an option for a 36 week extension of the study drug trial.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03408080
Study type Interventional
Source University of California, Los Angeles
Contact
Status Active, not recruiting
Phase Phase 3
Start date December 15, 2017
Completion date December 15, 2024

See also
  Status Clinical Trial Phase
Recruiting NCT05973019 - rTMS Improves Functions in Spinocerebellar Ataxia N/A
Completed NCT04837027 - Effect of Training on Brain Volume in Ataxia N/A
Completed NCT04595578 - Cerebellar rTMS and Physical Therapy for Cerebellar Ataxia N/A
Completed NCT03745248 - Aerobic Exercise, Balance Training, and Ataxia N/A
Completed NCT05951010 - Cerebellar Transcranial Direct Current Stimulation in Spinocerebellar Ataxia 38 N/A
Completed NCT01037777 - RISCA : Prospective Study of Individuals at Risk for SCA1, SCA2, SCA3, SCA6, SCA7
Completed NCT00136630 - Natural History, Genetic Bases and Phenotype-genotype Correlations in Autosomal Dominant Spinocerebellar Degenerations
Completed NCT03687190 - Could Tai-chi Help Maintain Balance of Spinocerebellar Ataxia Patients N/A
Active, not recruiting NCT03701399 - Troriluzole in Adult Subjects With Spinocerebellar Ataxia Phase 3
Completed NCT05436262 - Using Real-time fMRI Neurofeedback and Motor Imagery to Enhance Motor Timing and Precision in Cerebellar Ataxia N/A
Recruiting NCT04231487 - Using Wearable and Mobile Data to Diagnose and Monitor Movement Disorders
Withdrawn NCT04301284 - Study of CAD-1883 for Spinocerebellar Ataxia Phase 2
Not yet recruiting NCT06397274 - Stemchymal® for Polyglutamine Spinocerebellar Ataxia Phase 2
Not yet recruiting NCT06177626 - Impact of Exercise on Eyeblink Conditioning in Spinocerebellar Ataxias N/A
Recruiting NCT04529252 - Investigating the Genetic and Phenotypic Presentation of Ataxia and Nucleotide Repeat Diseases
Completed NCT05621200 - Transcranial Alternating Current Stimulation (tACS) in Patients With Ataxia N/A
Completed NCT03701776 - Ataxia and Exercise Disease Using MRI and Gait Analysis N/A
Completed NCT03120013 - Rehabilitative Trial With Cerebello-Spinal tDCS in Neurodegenerative Ataxia N/A
Active, not recruiting NCT02960893 - Trial in Adult Subjects With Spinocerebellar Ataxia Phase 2/Phase 3
Completed NCT04153110 - Cerebello-Spinal tDCS as Rehabilitative Intervention in Neurodegenerative Ataxia N/A