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Postoperative Oral Methadone After Major Spine Surgery; Safety, Feasibility and Efficacy in Prevention of Progression to Chronic Opioid Usage at 3 Months

Spine Surgery Clinical Trial

Official title:
Postoperative Oral Methadone After Major Spine Surgery; Safety, Feasibility and Efficacy in Prevention of Progression to Chronic Opioid Usage at 3 Months - A Pilot Trial.

Clinical Trial Summary

The purpose of this study is to evaluate the feasibility and safety of a clinical protocol based on the administration of intraoperative intravenous methadone followed by a short regimen of oral/IV (if the patient is not able to take oral) methadone following spine surgery and to evaluate if methadone decreases persistent opioid usage at 3 months in comparison to placebo.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05693675
Study type Interventional
Source The University of Texas Health Science Center, Houston
Contact Shobana Rajan, MD
Phone 713-500-6200
Email Shobana.Rajan@uth.tmc.edu
Status Not yet recruiting
Phase Phase 2/Phase 3
Start date October 1, 2023
Completion date July 1, 2024
View Details
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