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Spine Surgery clinical trials

View clinical trials related to Spine Surgery.

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NCT ID: NCT06439953 Not yet recruiting - Clinical trials for Surgical Site Infection

Impact of Prophylactic Use of Irrisept Irrigation System for Spinal Instrumentation

Start date: June 2024
Phase: N/A
Study type: Interventional

Various spine surgeons perform wound irrigation using saline mixed with vancomycin, relying on mechanical debridement of non-viable tissue, physical disruption of biofilm, and bacteriostatic effect against gram positive flora. When used as a powder, topical application of vancomycin has demonstrated increased risk of symptomatic seroma formation, which is an adverse outcome that often requires bedside or intra-operative aspiration. Broad-spectrum antiseptic agents, such as Irrisept, offer bacteriocidal properties to eliminate hardware inoculation, thereby minimizing the risk of deep space infection, while obviating the risk of seroma development.

NCT ID: NCT06267248 Enrolling by invitation - Spine Surgery Clinical Trials

Spine Registration Using 3D-Scanning

BWH
Start date: February 2024
Phase:
Study type: Observational

The primary objective is to assess the capability of the device as measured by its consistency, its accuracy, and feedback from surgical staff over the study period.

NCT ID: NCT06210061 Recruiting - Dexmedetomidine Clinical Trials

Propofol-Fentanyl-Dexmedetomidine and Propofol-Fentanyl-Sevoflurane Anesthesia for Major Spine Surgery Under Somato Sensory- and Motor- Evoked Potential Monitoring

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

The objective of this study is to evaluate the effect of adding dexmedetomidine on evoked potentials in adult patients undergoing spinal surgery under intravenous anesthesia

NCT ID: NCT05986006 Enrolling by invitation - Spine Surgery Clinical Trials

Fusion Status After ACDF

Start date: August 7, 2023
Phase: N/A
Study type: Interventional

Pseudarthrosis, a failure of bony fusion, is one of the most common causes of revision surgery following anterior cervical discectomy and fusion (ACDF). The interbody spacer is an important component of bony fusion in ACDF, and we aim to compare machined allograft spacers versus iliac crest allograft in a randomized controlled trial.

NCT ID: NCT05887375 Enrolling by invitation - Spine Surgery Clinical Trials

Sugammadex vs Neostigmine/Glycopyrrolate on Urinary Retention After Spine Surgery

Start date: August 3, 2023
Phase: Phase 4
Study type: Interventional

This is an active-comparator controlled study to evaluate the effect of sugammadex compared to neostigmine/glycopyrrolate for reversal of rocuronium on the incidence of urinary retention after subjects undergo elective ambulatory spine surgery.

NCT ID: NCT05857410 Completed - Spine Surgery Clinical Trials

Scheme of Limb Warming Blanket Combined With Dexmedetomidine

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

Objective: To observe the clinical effect of lower limb warming blanket combined with dexmedetomidine (DEX) in preventing postoperative delirium (POD) and chills in elderly patients undergoing spinal surgery. Methods: A total of 160 elderly patients undergoing posterior spinal surgery under general anesthesia were selected and divided into control group (group N), heating group (group T), DEX group (group D) and heating combined with DEX group (group TD) according to the random number table method, 40 cases in each group. T group and TD group routine insulation and lower limb heating blanket. DEX was injected in group D and group TD. The dosage of anesthetics, the changes of body temperature and heart rate at different time points during operation, and the occurrence of postoperative chills and POD were compared among the groups.

NCT ID: NCT05740865 Completed - Spine Surgery Clinical Trials

Risk Factors Associated With Infection After Spine Surgery

Start date: January 1, 2012
Phase:
Study type: Observational

Surgical site infection (SSI), particularly deep SSI, is one of the most serious complications after spinal surgery. evaluating the risk of SSI and, correspondingly, prescription of prophylactic measures are extremely important to prevent SSI and avoid potentially devastating consequences. A retrospective study was conducted aiming to develop a point-based prediction model of deep surgical site infection in patients receiving open posterior instrumented thoracolumbar surgery.

NCT ID: NCT05693675 Not yet recruiting - Spine Surgery Clinical Trials

Postoperative Oral Methadone After Major Spine Surgery; Safety, Feasibility and Efficacy in Prevention of Progression to Chronic Opioid Usage at 3 Months

Start date: October 1, 2023
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to evaluate the feasibility and safety of a clinical protocol based on the administration of intraoperative intravenous methadone followed by a short regimen of oral/IV (if the patient is not able to take oral) methadone following spine surgery and to evaluate if methadone decreases persistent opioid usage at 3 months in comparison to placebo.

NCT ID: NCT05626868 Recruiting - Spine Surgery Clinical Trials

Changes of Intra Abdominal Pressure During Surgeries in Prone Position as a Marker of Renal Damage

Start date: May 1, 2021
Phase:
Study type: Observational

Background: Patients undergoing surgical operations in prone position do not have a measure of intra abdominal pressure as a standard procedure. Many of them could have elevated values of this parameter and could be exposed to possible renal damage due to a stiffening of the abdominal muscles while being positioned prone. Purpose of study: Intraoperative intrabdominal pressure measurement and evaluation of correlation with possible postsurgical complications. Methodology: Electronic device able to measure intra abdominal pressure is connected between a Foley catheter and a urinary collecting bag. During the procedure, values of the intra abdominal pressure are displayed on a monitor next to anaesthetic machine in real time. The numbers representing the pressure in mmHG are assessed and recorded. Discussion: Possible correlation between intra abdominal hypertension and postsurgical complications in patients operated in prone position could be a foundation to further clinical trials and presurgical assessment of intraabdominal pressure.

NCT ID: NCT05561322 Withdrawn - Spine Surgery Clinical Trials

3rd-year Post-surgical Evaluation of Adjacent Segment Disc Degeneration Onset in Lumbar Spine (Spinal Fusion vs. Lumbar Arthroplasty With Disc Replacement)

ARTHRO-DEGE
Start date: February 27, 2024
Phase:
Study type: Observational

The main objective of the study is to compare the onset of adjacent segment disk degeneration in two groups of patients (one "spinal fusion group" and one "lumbar arthroplasty with disc replacement" group) with each patient acting as their own control for either group under study and more than three years of follow-up.