Clinical Trials Logo

Spinal Stenosis clinical trials

View clinical trials related to Spinal Stenosis.

Filter by:

NCT ID: NCT03910335 Completed - Clinical trials for Lumbar Spinal Stenosis

Diagnostic Screening Tool for Lumbar Spinal Stenosis

LSS Screen
Start date: February 19, 2019
Phase:
Study type: Observational

The aim of this project is to develop a questionnaire that should distinguish patients with lumbar spinal stenosis (LSS) from other patients. LSS can cause significant pain and disability leading to dramatically reduced quality of life, immobility and functional limitation. The number of people with pain and disability due to LSS is expected to increase with age due to the degenerative nature of the disease. With an aging population this could potentially become a major health economic challenge. One of the challenges to estimate the true prevalence is the lack of a valid and reliable gold standard for LSS. To our knowledge, no diagnostic screening tool designed to estimate the prevalence of LSS in a clinical population of Danish patients with chronic low back pain (LBP) and leg pain has been developed. The objective of this project is to develop a diagnostic screening tool for LSS - the LLS Screen. This should consist of a set of items useable in a self-administered questionnaire, a rule to compute the probability of having LSS, and a cutpoint to be used to obtain a sensitivity of 95%. The rule should be applicable in patient populations suffering from low back pain and with increased suspicion to suffer from LSS due to failure of non-surgical treatment

NCT ID: NCT03898232 Completed - Clinical trials for Degenerative Disc Disease

Fibergraft Interbody Fusion Retrospective

FIFR
Start date: May 9, 2019
Phase:
Study type: Observational

A single center study of clinical and radiological outcomes in a retrospective cohort of patients treated with Lumbar Interbody Fusion augmented with Prosidyan Fibergraft for 1 or 2 level degenerative spinal disease by a single surgeon. Study Design: Retrospective chart review with prospective data collection.

NCT ID: NCT03891745 Completed - Clinical trials for Lumbar Spinal Stenosis

Prone or Supine Extubation in Lomber Spinal Surgery

Start date: November 1, 2018
Phase:
Study type: Observational

The aim of this study was to investigate the emergence quality of patients extubated on prone or supine position after lumbar spinal surgery. 60 patients with ASA I-II who underwent lumbar spinal surgery between 18-65 years of age were included in the study. Patients with difficult intubation, BMI> 35kg / m2, asthma and reactive airway problems, cardiovascular disease and obstructive sleep apnea will not be included in the study. Initial data will be recorded after standard monitorization. Induction is made by 2 mg / kg propofol, 1 mg / kg fentanyl and 0.5 mg / kg rocuronium will be added for muscle relaxation. Patients with adequate muscle relaxation will be intubated with appropriate endotracheal tube and mechanical ventilation will be initiated. Patients who are then given prone positions on the operating table will be supported with side gels. The head will be placed in the face gel in a neutral position. For intraoperative analgesia, remifentanil infusion at 0.2mcg / kg / min will be applied. After laminectomy is completed and control of bleeding, 1 mg / kg Tramalol and 2 mg / kg Metaclopromide will be applied to all patients. At the end of the skin stitching, the inhalation agent will be closed and the fresh gas will be turned 6 lt 100% O2. Patients who want to be extubated in the prone position are left in this position while the other patients will be placed on the stretcher in a supine position for a short time. Patients will be decurarized be neostigmin with atropine. Extubation will be performed in both positions when spontanous ventilation begins at a tidal volume of 6ml / kg and a frequency of 12-20 / min. All the measures will be taken to ensure airway safety while the patient is extubated pron. The stretcher will be brought to the side of the operating table, investigator will be ready for reintubation and all the necessary persons will be with the patient. Aspiration frequency will be recorded for each patient. During recovery after extubation, the severity of cough will be evaluated as mild (only once), less (more than one but not continuous) and severe (continuously for 5 seconds). Aldrate scores of patient will be recorded and first 9-10 time is estimated from extubation time. Vomiting, nausea, respiratory insufficiency, inability to control the airway and obvious desaturation if seen are also recorded.

NCT ID: NCT03884283 Completed - Clinical trials for Degenerative Disc Disease

Prospective, Multi-center Study to Assess Posterolateral Fusion Using FIBERGRAFT

Start date: February 19, 2019
Phase: N/A
Study type: Interventional

This is a prospective, non-randomized (single arm), multi-center, post-market clinical study designed to evaluate FIBERGRAFT® BG Matrix mixed with autograft and bone marrow aspirate in up to 150 subjects with degenerative disc disease (DDD) with or without radiculopathy, or spinal stenosis and/or spondylolisthesis requiring a fusion. The patient population will include adult (skeletally mature) men and women undergoing 1 or 2 level fusion in the lumbar spine (L2-S1) who are deemed eligible for the study, characterized by inclusion and exclusion criteria.

NCT ID: NCT03883022 Recruiting - Spinal Stenosis Clinical Trials

Vancomycin Powder Combined With Autogenous Bone Graft as a Prevention for Post-operative Infection for Spine Surgery

Start date: September 3, 2018
Phase: N/A
Study type: Interventional

Deep surgical site infection (DSSI) is one of the most challenging complications for spinal surgeons and can lead to a poor clinical outcome. This ambispective study was designed to examine the effect of vancomycin powder mixed with autogenous bone graft and bone substitute on preventing deep surgical site infection (DSSI) in degenerative lumbar fusion surgeries as well as any interference with bony fusion.

NCT ID: NCT03879447 Active, not recruiting - Low Back Pain Clinical Trials

Effectiveness and Safety of Korean Medicine for Low Back Pain or Sciatica Due to Lumbar Stenosis/Spondylolisthesis

Start date: June 24, 2019
Phase:
Study type: Observational

A prospective observational study investigating the effectiveness and safety of integrative Korean medicine treatment in lumbar stenosis or spondylolisthesis patients with low back pain or sciatica at 3 locations of Jaseng Hospital of Korean Medicine as assessed through of pain, functional disability, walking ability, and quality of life patient-reported outcomes

NCT ID: NCT03867630 Not yet recruiting - Clinical trials for Lumbar Spinal Stenosis

The Effect of Additional Transforaminal Epidural Blocks in Percutaneous Epidural Neuroplasty

Start date: May 10, 2019
Phase:
Study type: Observational

Percutaneous epidural neuroplasty (PEN) is an effective interventional treatment for radicular pain. But in some cases with wire catheter like Racz catheter, contrast runoffs were not shown to the foramen. This study will show that contrast runoff will affect the results of PEN and in cases which contrast runoff are not shown, additional transforaminal epidural blocks will affect the results of PEN by reviewing medical record, retrospectively.

NCT ID: NCT03863769 Completed - Clinical trials for Spinal Stenosis Lumbar

Chiropractic Distraction Spinal Manipulation- Lumbar Stenosis Study

Stenosis
Start date: March 14, 2019
Phase:
Study type: Observational

To assess the effect of chiropractic distraction manipulation on postural sway and simple measures of performance in patients with the clinical diagnosis of lumbar spinal stenosis.

NCT ID: NCT03863067 Completed - Clinical trials for Spinal Stenosis, Lumbar Region, With Neurogenic Claudication

Clinical Effectiveness, Security And Radiological Changes In Epiduroscopy For Lumbar Stenosis

Start date: October 15, 2018
Phase: N/A
Study type: Interventional

It will be done a prospective Study involving 38 patients with lumbar stenosis. A magnetic resonance (MR) imaging study and a electromyographic study will be done previously and 3 months after the epiduroscopy to confirm radiologic or neurophysiological changes. During the technic it will be used different instruments, an endoscope developed for its use in the epidural space (Resascope), a Fogarty balloon (Resaloon) to dilate the space near the epidural recess where it will be try to decrease the ligamentum flavum using the Resaflex, an instrument with Quantum Molecular Resonance for tissue coablation, in order to get less symptomatic lumbar stenosis. The investigators will compare qualitative and quantitative variables at baseline and 1, 3, 6, ant 12 months after the epiduroscopy.

NCT ID: NCT03853356 Recruiting - Clinical trials for Lumbar Spinal Stenosis

Evidence For Fusion In Spine With Orthoss®

EFFISO
Start date: January 18, 2019
Phase:
Study type: Observational

This study aims to evaluate the performance and safety of the Orthoss® as a bone graft extender in lumbar spondylodesis involving 1-2 levels (L4-L5 and/or L5-S1).