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Spinal Stenosis clinical trials

View clinical trials related to Spinal Stenosis.

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NCT ID: NCT00939406 Completed - Clinical trials for Degenerative Spinal Stenosis

Clinical Trial to Evaluate Safety and Efficacy of Hyalospine® in Lumbar Laminectomy or Laminotomy

Hyalospine
Start date: November 2009
Phase: Phase 2/Phase 3
Study type: Interventional

The aim of this Phase II trial is to evaluate safety and efficacy of Hyalospine in patients undergoing lumbar laminectomy or laminotomy for degenerative spinal stenosis or disk herniation. The device is used as an adjunct in lumbar spine surgery to prevent post- surgical fibrosis and adhesions, and improve patient outcomes.

NCT ID: NCT00908375 Completed - Spinal Stenosis Clinical Trials

Efficacy of Pregabalin in Patients With Radicular Pain

Start date: May 2009
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate whether pregabalin is effective in reducing the pain in patients who present with radicular pain due to a herniated disc, spinal stenosis or failed back surgery syndrome.

NCT ID: NCT00905359 Completed - Spinal Stenosis Clinical Trials

Neurogenic Intermittent Claudication Evaluation Study

NICE
Start date: January 2010
Phase: Phase 4
Study type: Interventional

The objective of the NICE study is to provide clinical evidence proving that the Aperius™ PercLID™ System is safe and non-inferior to standalone decompressive surgery with regards to clinical outcomes in patients suffering from Degenerative Lumbar Spinal Stenosis with Neurogenic Intermittent Claudication, relieved by flexion.

NCT ID: NCT00887744 Completed - Spinal Stenosis Clinical Trials

Intermittent Neurogenic Claudication Treatment With APERIUS®

INCA
Start date: November 2006
Phase: Phase 4
Study type: Interventional

The primary purpose of the study is to measure the change in severity of symptoms and ability to function in every day activities in patients suffering from degenerative lumbar spinal stenosis after treatment with the Aperius® device.

NCT ID: NCT00808665 Completed - Spinal Stenosis Clinical Trials

Intraoperative Infusion of Precedex to Reduce Length of Stay After Lumbar Spine Fusion

DEXREDLOS
Start date: June 2009
Phase: Phase 4
Study type: Interventional

Major lumbar spine surgery causes inflammation, soreness and swelling that can delay discharge from the hospital. Dexmedetomidine (DEX) has been shown to have anti-inflammatory effects. This study will evaluate whether DEX can help get patients out of the hospital faster after major spine surgery by reducing the inflammation associated with the procedure itself. A separate part of the study will evaluate the blood levels of some specific indicators of inflammation called cytokines. Measuring cytokines before and after surgery will aid in determining if DEX has altered the inflammatory response.

NCT ID: NCT00786981 Completed - Clinical trials for Lumbar Spinal Stenosis

Epidural Steroid Injection Versus Epidural Steroid Injection and Manual Physical Therapy and Exercise in the Management of Lumbar Spinal Stenosis

Start date: April 2009
Phase: N/A
Study type: Interventional

Lumbar spinal stenosis (LSS) is a prevalent and disabling condition in the rapidly growing aging population. People with LSS often have a substantial physical and psychosocial burden as well as significant healthcare costs affecting both the individual and society. It has been reported that patients with LSS over the age of 65 are more likely to undergo spinal surgery than any other condition with an estimated total annual inpatient expense of one billion. Individuals undergoing surgical treatment for LSS tend to be older, therefore operative morbidity and mortality are a particular concern. Functional benefit derived from conservative treatment may increase the health and quality of life for individuals suffering from LSS and avoid or delay the need for surgery in some subjects. As the population continues to age, identifying effective non-surgical treatment options for older patients with LSS is an important research priority. Ultimately, the information gained from this study will help fill a significant void in medical literature regarding non-surgical options for this patient population.

NCT ID: NCT00749073 Completed - Clinical trials for Lumbar Spinal Stenosis

The Vertos MILD™ Preliminary Patient Evaluation Study

Start date: September 2008
Phase: N/A
Study type: Interventional

This is a single-center, open label, prospective clinical study to assess the clinical application and functional outcomes of symptomatic patients undergoing the Minimally Invasive Lumbar Decompression (MILD™) treatment for lumbar spinal stenosis. In this study, patient-reported outcomes over a 3 month period following treatment will be collected by the investigator. Periodic surveys for each study subject's pain, functional status, quality of life and physical examination will track outcomes following MILD™ treatment.

NCT ID: NCT00726284 Completed - Clinical trials for Degenerative Disc Disease

Spine Patient Outcomes Registry for Biomet/EBI (Electro-Biology, Inc)

SPO
Start date: April 2004
Phase:
Study type: Observational

The purpose of this patient registry is to prospectively collect data on patients who are having spinal surgery with EBI and Interpore Cross Spine Products.

NCT ID: NCT00692276 Completed - Clinical trials for Lumbar Spinal Stenosis

Investigating Superion™ In Spinal Stenosis

Start date: June 2008
Phase: N/A
Study type: Interventional

The proposed prospective, multi-center, randomized clinical trial is designed to evaluate the safety and effectiveness of the Superion™ ISS compared to the X-STOP® IPD® device in healthy adults suffering from at least 6 months of moderate spinal stenosis symptoms who have been unresponsive to conservative care.

NCT ID: NCT00638443 Completed - Clinical trials for Lumbar Spinal Stenosis

Lumbar Stenosis Outcomes Research (LUSTOR)

LUSTOR
Start date: March 2008
Phase: Phase 4
Study type: Observational

The primary objective of the proposed pilot study is to determine the efficacy of pregabalin in prolonging the time to onset of pain and reducing the severity of pain associated with walking in patients with neurogenic intermittent claudication. The secondary objective is to examine the functional benefit of pregabalin with respect to improvement in duration and distance of walking tolerance. The proposed study will also provide the foundation for a treadmill-based methodology for assessing the analgesic efficacy of drugs for low back pain provoked by standing and walking associated with lumbar spinal stenosis.