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Spinal Stenosis clinical trials

View clinical trials related to Spinal Stenosis.

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NCT ID: NCT02134821 Completed - Clinical trials for Lumbar Spinal Stenosis

Influence of Pain Sensitivity on Lumbar Surgery Outcomes

Start date: June 2012
Phase: N/A
Study type: Observational

Pain sensitivity would be associated with surgical outcomes after lumbar spine surgery.

NCT ID: NCT02127008 Completed - Spinal Stenosis Clinical Trials

The Impact of Epidural Fat Resection on Postoperative Outcomes in Posterior Surgery of Lumbar Spine

Start date: February 2013
Phase: N/A
Study type: Interventional

Posterior lumbar epidural fat commonly had been considered a simple space-filling tissue. Anatomic studies on posterior epidural space and its contents are few, including semifluid property. In other words, there has not been studied thoroughly regarding the significance and role of posterior epidural fat in lumbar spine. In adults, epidural fat situated in the posterior triangle limited by the lamina, the ligamentum flavum, and the posterior surface of thecal sac. The fat tissue was covered by a thin membrane of connective tissue, which were free under this layer. The anterior surface of this membrane lay close to the dura mater without any attachment. To date, the epidural fat has been resected routinely by pituitary forcep and suction drainage during posterior lumbar surgery. However, the investigators focused on the role of epidural fat, which might be associated with postoperative outcome. The investigators thought that this peculiar character, epidural fat, should be caused by certain etiologies. In general, each tissue, such as epidural fat, has its inherited features and significance, thereby the epidural fat has also specific role. However, there has not been fully studies regarding it. Thus, the investigators aimed to evaluate the impact of the posterior epidural fat on the postoperative outcomes such as pain intensity and functional outcomes by whether the epidural fat would be resected or not during posterior decompressive surgery. The investigators hypothesized that the epidural fat would be associated with postoperative pain intensitive, functional outcomes, and complications of the surgery such as failed back surgery syndrome. In this study, new device for resection of epidural fat was not utilized, but just resected with conventional devices such as pituitary forcep.

NCT ID: NCT02121249 Completed - Clinical trials for Degenerative Lumbar Spinal Stenosis

Clinical Trial of Minimally Invasive Robotic Spine Surgery

Start date: December 2013
Phase: N/A
Study type: Interventional

The purpose of this study was to quantify potential short- and long-term benefits of robotically-guided minimally invasive spine surgery in instrumentation of degenerative lumbar or lumbosacral spine disease in adult patients, in comparison to instrumentation in a matching cohort of control patients performed using conventional freehand technique.

NCT ID: NCT02093520 Completed - Clinical trials for Spinal Stenosis, Lumbar Region, With Neurogenic Claudication

The MiDAS ENCORE Study

Start date: May 2014
Phase: N/A
Study type: Interventional

Study Objective: To compare patient outcomes following treatment with either the MILD procedure or epidural steroid injections (ESIs) in patients with painful lumbar spinal stenosis exhibiting neurogenic claudication and having verified ligamentum flavum hypertrophy as a contributing factor.

NCT ID: NCT02090244 Completed - Spinal Stenosis Clinical Trials

Does PTH 1-34 (Teriparatide) Enhance Spinal Fusion in Humans?

Start date: August 2012
Phase: Phase 4
Study type: Interventional

Parathyroid (PTH) hormone has been shown to enhance fracture healing in animal studies. There are so far only three published papers concerning humans. Postero-lateral fusions have shown a healing rate of less than 50% after bone. The purpose of this study is to determine if PTH 1-34 (teriparatide) improves the healing rate and the clinical course after spinal stenosis surgery.

NCT ID: NCT02079038 Completed - Clinical trials for Lumbar Spinal Stenosis

The STEPS - Totalis™ Trial

Start date: May 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to determine safety and effectiveness, as measured by changes in pain, disability, patient satisfaction, and claudicatory symptoms, at 6 months following treatment with the Totalis™ Direct Decompression System or Sham Comparator Surgical Procedure in patients with lumbar spinal stenosis

NCT ID: NCT02063035 Completed - Clinical trials for Lumbar Spinal Stenosis

Effectiveness Study of the Drug Tranexamic Acid to Reduce Post-surgery Blood Loss in Spinal Surgery

Start date: August 2012
Phase: Phase 4
Study type: Interventional

Hypothesis: Topical application of Tranexamic acid into the surgical wound during spine surgery will decrease the overall blood loss post-operatively. This reduction in blood loss will reduce the need for transfusion. In addition it will also significantly reduce the cost of the surgical procedure. Specific Aim 1: The goal of this study is to quantitatively assess whether topical application of tranexamic acid placed into the surgical wound during lumbar spine surgery will decrease post-operative blood loss, thus lowering the need for blood transfusions. By reducing the number of transfusions participants can avoid the well-known complications associated with them. The investigators do not plan on measuring serum tranexamic acid levels. Several meta-analyses and level I studies have shown that intravenous (IV) administration of tranexamic acid is effective in reducing postoperative blood loss and the need for transfusion.

NCT ID: NCT02039232 Completed - Clinical trials for Degenerative Disc Disease

Safety and Efficacy of the CarboFix Pedicle Screw System

Start date: January 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of CarboFix' Pedicle Screw System in the lumbar spine.

NCT ID: NCT02023372 Completed - Spinal Stenosis Clinical Trials

Efficacy Study of NuCel® in Patients Undergoing Fusion of the Lumbar Spine

Start date: December 2013
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether NuCel is effective in promoting spinal fusion in degenerative disease of the lumbar spine.

NCT ID: NCT02006901 Completed - Spinal Stenosis Clinical Trials

Comparative Effectiveness of Microdecompression and Laminectomy for Central Lumbar Spinal Stenosis

Start date: January 2014
Phase: N/A
Study type: Observational

Introduction: This observational study is designed to test the equivalence between the clinical effectiveness of microdecompression and laminectomy in the surgical treatment of central lumbar spinal stenosis. Lumbar spinal stenosis is the most frequent indication for spinal surgery in the elderly, and as the oldest segment of the population continues to grow its prevalence is likely to increase. However, data on surgical outcomes are limited. Open or wide decompressive laminectomy, often combined with medial facetectomy and foraminotomy, was formerly the standard treatment. In recent years a growing tendency towards less invasive decompressive procedures has emerged. Many spine surgeons today perform microdecompression for central lumbar spinal stenosis. Prospectively registered treatment and outcome data are obtained from the Norwegian Registry for Spine Surgery (NORspine).