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Spinal Neoplasms clinical trials

View clinical trials related to Spinal Neoplasms.

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NCT ID: NCT05170815 Recruiting - Spinal Deformity Clinical Trials

Clariance ErYs Registry

ErYs
Start date: January 17, 2022
Phase:
Study type: Observational

International, prospective, single arm, multicenter and observational Post-Market Clinical Follow-up (PMCF). The overall objective of this study is to collect preoperative, intraoperative and postoperative (at 9 weeks, 6 months, 1 year and 2 years) data on the clinical complications and functional outcomes of the study devices to demonstrate safety and performance in a real-world setting. The primary objective is to demonstrate that the use of the study devices is safe. The secondary objective is to demonstrate that the use of the study devices decreases the pain, and improves the quality of life and the daily activities of the subjects.

NCT ID: NCT05106179 Enrolling by invitation - Spinal Tumor Clinical Trials

The Efficacy and Safety of Beta-blockers Drugs in Adults With Spinal Hemangioma

Start date: December 2021
Phase: Phase 4
Study type: Interventional

Spinal hemangioma is one of the most common benign vertebral tumours. Being mostly asymptomatic, it is still associated with a pain syndrome especially if encroaches into the neural canal. This study is organised to evaluate the efficacy and safety of β-blockers drugs in adults with spinal hemangioma.

NCT ID: NCT05096468 Completed - Clinical trials for Perioperative Complication

Esketamine Combined With Pregabalin on Acute Postoperative Pain in Patients Undergoing Resection of Spinal Neoplasms.

Start date: December 1, 2021
Phase: Phase 2/Phase 3
Study type: Interventional

Postsurgical pain is now known to be one of the most common and difficult-to-treat complications of surgery. severe postoperative pain can significantly impair patients' quality of life, social functioning and contribute to excessive health care expenditures. It is worth noting that acute postoperative pain may play a vital role in central sensitization and up-regulation of pain receptors, even factors implicated in the development of CPSP. According to previous studies, the incidence of postoperative pain among patients undergoing spinal surgery was nearly 80%. At the same time, perioperative pain management of patients undergoing spinal surgery has not been clearly. For the past few years, pregabalin and esketamine are becoming important roles in perioperative pain management, lots of studies have shown that these two analgesics might relieve postoperative pain. The aim of this study was to evaluate the acute analgesic effects of esketamine and pregabalin in combination after spinal cord neoplasms resection, so as to find a better way to help the patients undergoing spinal surgery keep away from the acute perioperative pain.

NCT ID: NCT05060653 Withdrawn - Surgery Clinical Trials

Stereotactic Body Radiotherapy Followed by Surgical Stabilization in Spinal Metastases

BLEND-II
Start date: October 2022
Phase: N/A
Study type: Interventional

The aim of this study is to assess pain response after combining stereotactic body radiotherapy (SBRT) and pedicle screw fixation in a 48-hour window for the treatment of painful unstable metastases of the thoracic and/or lumbar spine.

NCT ID: NCT04968730 Recruiting - Clinical trials for Tumor of Spinal Cord

Establishment and Application of Early Postoperative Activity Plan for Patients After Hemi-laminectomy for Lumbar Spinal Tumor Resection

Start date: May 11, 2021
Phase: N/A
Study type: Interventional

Objective to construct the related early activity program for patients with lumbar intraspinal tumor after hemilaminectomy, and evaluate the postoperative limb function exercise according to the content of the program. In order to improve the self-care ability and quality of life of patients, reduce postoperative complications, shorten the average length of stay, reduce hospitalization expenses and improve patient satisfaction. Objective to evaluate the efficacy and safety of establishing early activity program after hemilaminectomy for patients with lumbar intraspinal tumors

NCT ID: NCT04957056 Recruiting - Intraspinal Tumor Clinical Trials

Finite Element Study of Biomechanical Changes After Unilateral Hemilamina and Facet Joint Resection of Cervical Spine

Start date: February 1, 2018
Phase:
Study type: Observational

Finite element method was used to simulate unilateral hemilaminectomy of cervical spine and facet joint resection of different degrees, and the range of motion and the stress changes of ligament, intervertebral disc and endplate were calculated immediately after operation

NCT ID: NCT04955522 Completed - Bone Tumor Clinical Trials

Multimodal Imaging Analysis of Spinal Tumors

Start date: December 1, 2019
Phase:
Study type: Observational

In this study, we retrospectively analyzed the imaging data of spinal tumors to find out more imaging features of spinal tumors, in order to provide more accurate reference for the diagnosis of spinal tumors.

NCT ID: NCT04952818 Completed - Spinal Tumor Clinical Trials

The Value of Preoperative Diagnosis and Prognostic Prediction Based on Radiomics of Giant Cell Tumor of Spine

Start date: January 1, 2020
Phase:
Study type: Observational

1. Exploit CT (plain scan), enhanced CT and fMRI based radiomic biomarkers, explore their correlation with the prognostic molecular markers of spinal GCTB(p53/vegf/rank/rankl…), and help accurate diagnosis of GCTB. 2. Exploring a new method of preoperative risk stratification for spinal GCTB, and establishing radiomic model combined with clinical features. Exploring the GCTB biological behavior prediction model and the prognosis prediction of GCTB.

NCT ID: NCT04578691 Completed - Spinal Tumor Clinical Trials

Study to Evaluate the Safety and Clinical Outcome of Using Navigation System in Pedicle Screw Placement in Spine Surgery

Start date: June 29, 2020
Phase: N/A
Study type: Interventional

The research project is testing whether in screw insertion of spine surgery using "Anatase" Spine Surgery Navigation System is at least as safe and accurate as using O-arm assisted spine surgery- Medtronic Stealthstation S7 Treatment Guidance System.

NCT ID: NCT04217525 Recruiting - Spinal Tumor Clinical Trials

Duke Spine Outcome Study (DSOS)

DSOS
Start date: December 3, 2019
Phase:
Study type: Observational [Patient Registry]

The primary goal of this registry is to increase the knowledge about spine tumors and other spine disorders to guide appropriate management strategies for the future. This registry will include the review of medical records, data collection for health related quality of life questionnaires, and collected tissues and samples. The study will require obtaining spinal lesions (tumor, etc.), blood, and bone marrow samples (from non-lesional bone) from selected patients, which will be collected during your surgery.