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Spinal Fusion Acquired clinical trials

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NCT ID: NCT02631408 Completed - Clinical trials for Spinal Fusion Acquired

Intrawound Vancomycin Powder in Spinal Fusion Surgery

iVRCT
Start date: August 2015
Phase: Phase 4
Study type: Interventional

Vancomycin powder (for solution for Infusion) will be investigated (off-label usage) in spinal fusion surgery. The powder will be locally administered into to the wound cavity before wound closure. Hypothesis: Locally applied vancomycin powder leads to a reduction in postoperative surgical site infections

NCT ID: NCT00808665 Completed - Spinal Stenosis Clinical Trials

Intraoperative Infusion of Precedex to Reduce Length of Stay After Lumbar Spine Fusion

DEXREDLOS
Start date: June 2009
Phase: Phase 4
Study type: Interventional

Major lumbar spine surgery causes inflammation, soreness and swelling that can delay discharge from the hospital. Dexmedetomidine (DEX) has been shown to have anti-inflammatory effects. This study will evaluate whether DEX can help get patients out of the hospital faster after major spine surgery by reducing the inflammation associated with the procedure itself. A separate part of the study will evaluate the blood levels of some specific indicators of inflammation called cytokines. Measuring cytokines before and after surgery will aid in determining if DEX has altered the inflammatory response.