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A Study of Autonomic Dynamic Dysfunction to Predict Infections After Spinal Cord Injury.

SPINAL Fracture Clinical Trial

Official title:
PROSPECT ADDITION SCI - A PROSPECTive Study of Autonomic Dynamic Dysfunction to Predict infecTIONs After Spinal Cord Injury

Clinical Trial Summary

The study is designed to investigate whether autonomic shifts (dysautonomia, sympatho-vagal instability) that develop after SCI have value in predicting SCI-associated infections (SCI-AI). SCI-AI impair outcomes by (1) reducing the intrinsic neurological recovery potential and (2) increasing mortality. Heart Rate Variability (HRV) data will be tracked in both the time and frequency domains to discriminate between the relative contribution of sympathetic and parasympathetic innervation to changes in HRV. The ability to predict infections will enable novel treatments thereby reducing infection-associated mortality and improving neurological and functional outcomes.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03253952
Study type Observational
Source Ohio State University
Contact Nathaniel B Dusseau, II, BS, MS
Phone 614-293-1454
Email nathaniel.dusseau@osumc.edu
Status Recruiting
Phase
Start date September 29, 2017
Completion date December 31, 2024
View Details
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