Clinical Trials Logo
  1. Home
  2. Spinal Diseases
  3. NCT03492372
  4. Details
NCT03492372 Clinical Trial

Molecular Characterization of Spinal Tissue

Spinal Diseases Clinical Trial

Official title:
Molecular Characterization of Spinal Tissue

Clinical Trial Details — Status: Enrolling by invitation

Administrative data
NCT number NCT03492372
Other study ID # 14-008177
Secondary ID
Status Enrolling by invitation
Phase
First received
Last updated
Start date March 31, 2015
Est. completion date July 2025

Study information
Verified date August 2023
Source Mayo Clinic
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The researchers are trying to identify molecular mechanisms that control spine deformity and degenerative changes that can be used for therapeutic strategies.

Description:

Discarded surgical material from spinal procedures is collected. RNA analysis and other tests on the tissue is performed to determine markers of pathologic disease and to develop pharmacologic treatment strategies for pediatric spinal disorders.

Recruitment information / eligibility
Status Enrolling by invitation
Enrollment 300
Est. completion date July 2025
Est. primary completion date July 2025
Accepts healthy volunteers No
Gender All
Age group 1 Year to 80 Years
Eligibility Inclusion Criteria: - Children and adults undergoing surgical procedures where spinal tissues are removed as a normal part of their procedure. Material from adults may be collected as a control group. Exclusion Criteria: - Surgeries where spinal tissues are not being removed.

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• Waste tissues are collected at the time of spinal surgery.
This is a single visit study. Waste tissues are collected at the time of spinal surgery.

Locations
Country Name City State
United States Mayo Clinic Rochester Minnesota

Sponsors (1)
Lead Sponsor Collaborator
Mayo Clinic

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary RNA expression Measure RNA levels in spinal tissues samples (ng/mL) Baseline
See also
  Status Clinical Trial Phase
Recruiting NCT05484557 - Prevention of Thromboembolism Using Apixaban vs Enoxaparin Following Spinal Cord Injury N/A
Not yet recruiting NCT02535273 - The Effect of Dexmedetomidine Analgesia and Sedation in Minimally Invasive Spine Surgery Under Local Anesthesia Phase 4
Recruiting NCT02187653 - Intraoperative Monitoring (IOM) Patient Registry N/A
Completed NCT00295009 - Safety and Effectiveness Study of Prodisc to Spinal Fusion Surgery N/A
Completed NCT03832036 - The Diagnostic and Prognostic Value of Two Quantitative Clinical Tests in Patients With Lumbar Disc Herniation N/A
Completed NCT03015142 - Observational Clinical Study to Plan, Position and Check Instrument Placement for Spine Surgery Interventions
Not yet recruiting NCT06123624 - Desflurane and Sevoflurane on Remifentanil Requirement N/A
Completed NCT03158766 - Subclinical Propionibacterium Acnes Infection Estimation in the Intervertebral Disc (SPInE-ID)
Not yet recruiting NCT02416557 - Effect of PEEP on Intraoperative Hypothermia N/A
Completed NCT02724111 - Effect of Neuromuscular Blockade on Operating Conditions and Overall Satisfaction During Spinal Surgery Phase 4
Completed NCT03753945 - Spine MRI in Patients With Deep Brain Stimulation (DBS) N/A
Terminated NCT03802656 - Vertebral Body Tethering Treatment for Idiopathic Scoliosis N/A
Recruiting NCT02809781 - A Pilot Study of MSCs Iufusion and Etanercept to Treat Ankylosing Spondylitis Phase 2/Phase 3
Not yet recruiting NCT02762656 - The Effect of Perioperative Lidocaine Intravenous Infusion on Postoperative Recovery After Spine Surgery. Phase 4
Completed NCT00756301 - Cutaneous Administration of Local Anesthetic for Spine Injection Procedures N/A
Completed NCT00808665 - Intraoperative Infusion of Precedex to Reduce Length of Stay After Lumbar Spine Fusion Phase 4
Completed NCT03562455 - Virtual Reality for Power Wheelchair Training N/A
Completed NCT00979108 - The Value of Traction in the Treatment of Cervical Radiculopathy Phase 3
Completed NCT01020929 - Incidence of Simultaneous Epidural and Intravascular Injection N/A
Completed NCT00942227 - The Value of Traction in Treatment of Lumbar Radiculopathy Phase 3

External Links