Clinical Trials Logo

Clinical Trial Summary

The purpose of this study is to evaluate the effectiveness of perioperative Lidocaine intravenous infusion in reducing postoperative pain for spine surgery patients.


Clinical Trial Description

Study design: this study used a prospective, randomized, double-blinded, and placebo-controlled clinical trial.

Sixty patients scheduled for a spine surgery will be randomly assigned to two groups. Lidocaine group will receive an intravenous bolus injection of lidocaine 1.5 mg/kg before intubation, followed by 2 mg/kg/h continuous infusion during the operation. Placebo group will receive the same dosage of saline at the same time. Analgesic requirement will be monitored using patient-controlled Analgesia (PCA protocol: demand dose is 2 mg of morphine, lockout 5 min, maximum dose 15 mg per hour). Forty-eight hours after surgery, we will check the morphine consumption in two groups. Quality of recovery after surgery will be assessed using Q0R15 questionnaire. ;


Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver), Primary Purpose: Treatment


Related Conditions & MeSH terms


NCT number NCT02762656
Study type Interventional
Source Sheba Medical Center
Contact Haim Berkenstadt, MD
Phone 03-5302754
Email Haim.Berkenstadt@sheba.health.gov.il
Status Not yet recruiting
Phase Phase 4
Start date June 2016
Completion date August 2017

See also
  Status Clinical Trial Phase
Recruiting NCT05484557 - Prevention of Thromboembolism Using Apixaban vs Enoxaparin Following Spinal Cord Injury N/A
Not yet recruiting NCT02535273 - The Effect of Dexmedetomidine Analgesia and Sedation in Minimally Invasive Spine Surgery Under Local Anesthesia Phase 4
Recruiting NCT02187653 - Intraoperative Monitoring (IOM) Patient Registry N/A
Completed NCT00295009 - Safety and Effectiveness Study of Prodisc to Spinal Fusion Surgery N/A
Completed NCT03832036 - The Diagnostic and Prognostic Value of Two Quantitative Clinical Tests in Patients With Lumbar Disc Herniation N/A
Completed NCT03015142 - Observational Clinical Study to Plan, Position and Check Instrument Placement for Spine Surgery Interventions
Not yet recruiting NCT06123624 - Desflurane and Sevoflurane on Remifentanil Requirement N/A
Completed NCT03158766 - Subclinical Propionibacterium Acnes Infection Estimation in the Intervertebral Disc (SPInE-ID)
Not yet recruiting NCT02416557 - Effect of PEEP on Intraoperative Hypothermia N/A
Completed NCT02724111 - Effect of Neuromuscular Blockade on Operating Conditions and Overall Satisfaction During Spinal Surgery Phase 4
Enrolling by invitation NCT03492372 - Molecular Characterization of Spinal Tissue
Completed NCT03753945 - Spine MRI in Patients With Deep Brain Stimulation (DBS) N/A
Terminated NCT03802656 - Vertebral Body Tethering Treatment for Idiopathic Scoliosis N/A
Recruiting NCT02809781 - A Pilot Study of MSCs Iufusion and Etanercept to Treat Ankylosing Spondylitis Phase 2/Phase 3
Completed NCT00756301 - Cutaneous Administration of Local Anesthetic for Spine Injection Procedures N/A
Completed NCT00808665 - Intraoperative Infusion of Precedex to Reduce Length of Stay After Lumbar Spine Fusion Phase 4
Completed NCT03562455 - Virtual Reality for Power Wheelchair Training N/A
Completed NCT00979108 - The Value of Traction in the Treatment of Cervical Radiculopathy Phase 3
Completed NCT01020929 - Incidence of Simultaneous Epidural and Intravascular Injection N/A
Completed NCT00942227 - The Value of Traction in Treatment of Lumbar Radiculopathy Phase 3