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Spinal Diseases clinical trials

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NCT ID: NCT06014645 Completed - Clinical trials for Lumbar Spine Disease

Effectiveness of Home Programs After Lumbar Spinal Decompression Surgery

Start date: June 14, 2023
Phase: N/A
Study type: Interventional

The study will be conducted with volunteer patients who are followed up by Bursa Çekirge State Hospital Cekirge State Hospital Neurosurgery outpatient clinic and who have undergone lumbar decompression surgery and who meet the study criteria. The cases will be divided into 2 groups by randomization software. The control group will receive post-operative exercise training and will be encouraged to move. The study group will receive a core stabilization program in addition to education via telerehabilitation. The first evaluation will be performed 2 months post-operatively and the second evaluation will be performed 2 months after treatment.

NCT ID: NCT06006377 Completed - Neck Pain Clinical Trials

Investigation of the Efficacy of Treatments With Backup Device in Spine Pathologies

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

Our aim in this study is to examine the effectiveness of the Backup spine health device in spinal problems and compare it with traditional physical therapy methods.

NCT ID: NCT05867732 Completed - Clinical trials for Degenerative Spine Diseases

A Multicenter Observational Cohort of Degenerative Spine Diseases in China(DSDC)

DSDC
Start date: March 1, 2022
Phase:
Study type: Observational [Patient Registry]

Study type: The objectives of this observational study were to understand, analyze, and compare the treatment and prognosis of patients with degenerative spine diseases and to construct a risk warning model and an assisted decision-making system The main questions it aims to answer are: - [question 1] to construct a database of patients with degenerative spinal diseases and to study their associated prognosis, complications, and other risks - [Question 2] Use big data to build a risk early warning model and assisted decision making system The study will not intervene with patients

NCT ID: NCT05693454 Completed - Surgical Wound Clinical Trials

Local Wound Anesthesia in Spine Surgery

Start date: November 1, 2021
Phase: N/A
Study type: Interventional

Prospective, randomized, double-blinded, trial regarding the effect of local wound infiltration at the end of spine surgery; randomizing 1:1:1 between NaCl, Ropivacain, Levobupivacaine combined with Tramadol

NCT ID: NCT05574543 Completed - Clinical trials for Degenerative Disc Disease

A Phase I/II Study of AGA111 for Lumbar Interbody Fusion in Patients With Degenerative Disc Disease

Start date: December 1, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

The objectives of the study are to evaluate the safety and preliminary efficacy of a single administration of AGA111 for lumbar interbody fusion in patients with degenerative disc disease.

NCT ID: NCT05525052 Completed - Spinal Stenosis Clinical Trials

Percutaneous Trans-facet Screw Fixation Under CT-scan Guidance for Remaining Symptoms at a Distance of Previous Spinal Surgery

Start date: January 1, 2021
Phase:
Study type: Observational

Background : Segmental spinal instability after a laminectomy, and adjacent segment disease (ASD) at after an arthrodesis, are well-known concerns in spinal surgery, which may require re-interventions, usually by surgical arthrodesis, posing the problem of a new heavy intervention under general anesthesia, in often fragile patients. Trans-facet fixation (TFF) under local anesthesia and double fluoroscopic and CT guidance is a minimally invasive technique involving the placement of screws through the posterior facet joints, improving spinal stability. Purpose : The aim of our study is to evaluate the efficacy, in terms of pain reduction (VAS) and improvement of daily activities (ODI), of TFF under CT scan guidance in the context of low back pain and/or radiculalgia related to focal instability secondary to laminectomy or ASD. Methods : TFF were performed in 24 patients having a history of spinal surgery such as laminectomy and/or classic surgical arthrodesis and remaining symptomatic, at Nice University Hospital between 2017 and 2021 Pre- and postoperative pain and disability levels were measured using the visual analogue scale (VAS) and the Oswestry Disability Index (ODI), collected prospectively at systematic 6-month and 1-year follow-up visits. Long term evolution were assessed by phone consultation.

NCT ID: NCT05453955 Completed - Spine Disease Clinical Trials

Effect of Remimazolam on Motor Evoked Potential

Start date: August 1, 2022
Phase: N/A
Study type: Interventional

This study was planned to investigate the degree of effect of remimazolam on MEP compared to propofol when monitoring the motion-inducing potential (MEP).

NCT ID: NCT05360199 Completed - Clinical trials for Degenerative Diseases, Spinal Cord

Are Postoperative Patient PROMS Influenced by Recall of Preoperative Scores?

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

To evaluate whether postoperative PROM scores of spine patients are influenced by memory bias

NCT ID: NCT05345249 Completed - Clinical trials for Lumbar Spinal Stenosis

Erector Spinae Plane Block as Pain Management After Lumbar Fusion Surgery

RCT-ESPB
Start date: June 1, 2022
Phase: Phase 4
Study type: Interventional

Rationale: Lumbar spine surgery is associated with high postoperative pain scores and analgesic use, despite use of multimodal analgesia. The erector spinae plane block (ESPB) is a promising locoregional anesthetic technique for this type of surgery. The literature is not yet conclusive about the effectiveness of this technique on reducing postoperative pain intensity. Objective: The objective of this study is to evaluate the analgesic effect of ESPB as add-on therapy to multimodal analgesia on early postoperative pain intensity after lumbar spinal fusion surgery compared to placebo. Study design: The study is designed as a prospective mono-centre, randomized, double-blinded, placebo-controlled trial. Study population: 76 patients ≥ 18 years of age requiring elective lumbar spinal fusion surgery involving one to four fusion levels. Intervention: Patients will receive ultrasound-guided ESPB with either ropivacaine or placebo at the end of surgery. Main study parameters/endpoints: Main study parameter is pain intensity upon emergence from anesthesia measured with the Numeric Rating Scale. A minimal clinically important difference is considered to be a decrease of 1.5 points. Secondary endpoints are pain intensity during hospital stay and after 30 days, opioid use during hospital stay and after 30 days, opioid side effects, use of anti-emetics, time to first opioid use/request, length of hospital stay, quality of recovery at discharge. Nature and extent of the burden and risks associated with participation, benefit and group relatedness: The Sint Maartenskliniek is experienced in applying locoregional analgesia, the use of ropivacaine and using sonography. The procedure of administering ESPB has a very low risk of complications. Receiving placebo is justifiable because this group will not be withhold standard treatment. The risks of receiving placebo are negligible. The patients will visit the clinic at regular follow-up moments.

NCT ID: NCT05266638 Completed - Clinical trials for Degenerative Lumbar Spine Diseases

Assessing Risk Factors for Radiological Complications After Transforaminal Lumbar Interbody Fusion

AgeTLIF
Start date: January 19, 2022
Phase:
Study type: Observational

This retrospective study is to determine whether age is a risk factor for postoperative complications in patients undergoing transforaminal lumbar interbody fusion; specifically whether the risk (odds) of implant failure and the need for revision surgery increases with age.