Virtual Single-energy Imaging and De-metallic Artifact Technology in Reducing Spinal Metallic Artifacts

Spinal Disease Clinical Trial

Official title:

A Comparative Study of Virtual Single-energy Imaging and De-metallic Artifact Technology in Reducing Spinal Metallic Artifacts

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04955483
• Other study ID #: M2018180
• Status: Completed
• Start date: December 1, 2018
• Est. completion date: February 1, 2019

Study information

• Verified date: December 2018
• Source: Peking University Third Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

1. Compare the effect of virtual single energy imaging and virtual single energy combined with MAR technology to remove metal artifacts in the spine. 2. Discuss the most suitable KeV of virtual single energy imaging combined with MAR technology to remove metal artifacts.

Description:

The virtual single-energy imaging of energy spectrum CT combined with the metal artifact reduction technology MARS Multi Artifact Reduction System] can effectively reduce the interference of metal artifacts. This is because MAR technology corrects the image through an iterative algorithm, improves the spatial resolution, and restores the details of the adjacent tissue of the metal object. Virtual single-energy imaging technology can effectively reduce hardening artifacts. The two are used in combination to achieve the purpose of reducing metal artifacts. There have been articles about virtual single energy combined with MAR technology to reduce metal artifacts. However, the current researches mostly focus on the comparison of virtual single energy combined with MAR technology and conventional CT examination and virtual single energy imaging. There are few evaluations on the severity of metal artifacts after spinal surgery. According to different surgical methods, metal The difference in the number of implants will result in different artifact reduction effects. Secondly, the current research on the suitable KeV of virtual single energy combined with MAR technology to reduce metal artifacts is less discussed and reported.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 43
• Est. completion date: February 1, 2019
• Est. primary completion date: December 3, 2018
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• Patients undergoing surgery due to lumbar disc herniation or prolapse
• Patients undergoing surgical correction due to vertebral deformities.

Exclusion Criteria:

• The scan image quality caused by the patient's movement and other factors is too poor to meet the diagnostic requirements.
• Patients with only spinous processes and intervertebral spaces undergoing metal fixation after spine surgery
• Patients after spinal cord tumor surgery.

Related Conditions & MeSH terms

• Spinal Disease
• Spinal Diseases

Intervention

Diagnostic Test:
• Virtual single energy combined with MAR reconstruction group
combined with MAR reconstruction group

Locations

Country	Name	City	State
China	Peking University Third Hospital	Beijing	Beijing

Sponsors (1)

Lead Sponsor	Collaborator
Peking University Third Hospital

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Artifact Index	Select the largest level of artifacts in the image, place a region of interest (ROI) with an area of 100-150mm2 in the soft tissue around the metal and spinal canal for CT value and standard deviation (SD) measurement, avoid the boundary area, and measure the ROI area Artifact Index ASelect the largest level of artifacts in the image, place a region of interest (ROI) with an area of 100-150mm2 in the soft tissue around the metal and spinal canal for CT value and standard deviation (SD) measurement, avoid the boundary area, and measure the ROI area Artifact Index AI	2019.2.1-2019.2.15