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Spinal Curvatures clinical trials

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NCT ID: NCT03802656 Terminated - Scoliosis Clinical Trials

Vertebral Body Tethering Treatment for Idiopathic Scoliosis

Start date: June 24, 2019
Phase: N/A
Study type: Interventional

This study will determine whether vertebral body tethering is a safe and feasible method of treatment for pediatric idiopathic scoliosis.

NCT ID: NCT03593330 Recruiting - Surgery Clinical Trials

Neurosurgical Transitional Care Programme

TCP
Start date: April 15, 2018
Phase: N/A
Study type: Interventional

Readmissions increasingly serve as a metric of hospital performance, inviting quality improvement initiatives in both medicine and surgery. Recently, a readmission reduction program in the United States was associated with significantly shorter length of stay, earlier discharge, and reduced 30-day readmission after elective neurosurgery. These results underscore the importance of patient education and surveillance after hospital discharge, and it would be beneficial to test whether the same approach yields beneficial results in a different health system, the NHS. In this study, the investigators will replicate the Transitional Care Program (TCP) published by Robertson et al.(Journal of Neurosurgery 2017) with the goal of decreasing length of stay, improving discharge efficiency, and reducing readmissions in neurosurgical patients by optimizing patient education and post-discharge surveillance.

NCT ID: NCT03533010 Recruiting - Scoliosis Clinical Trials

Preventing Curve Progression and the Need for Bracing in Adolescent Idiopathic Scoliosis With Calcium + Vitamin D Supplementation

Start date: July 1, 2018
Phase: N/A
Study type: Interventional

There is an association between adolescent idiopathic scoliosis (AIS) and low bone mass which has been reported to be a significant prognostic factor for curve progression. Given that dietary calcium (Ca) intake and serum Vit-D levels were also low in AIS, we therefore propose a randomized double-blinded placebo-controlled trial to evaluate if daily [500mg Ca + 800 IU Vit-D] can improve bone health and prevent curve progression in AIS. Immature AIS girls with Cobb angle 10-20 degrees will be randomized either to the Treatment or Placebo group with 3-year of treatment. The main outcome measures for evaluation for those who have completed the 3-year treatment and have reached skeletal maturity at the end of 3-year treatment include: (1) percentage of patients with increase in Cobb angleā‰„6 degrees and (2) percentage of patients who require bracing. Bone measurements using advanced image acquisition technology(HR-pQCT) to assess bone health will also be evaluated.

NCT ID: NCT03178708 Completed - Spinal Curvatures Clinical Trials

Amantadine Sulphate Usage in Spine Deformities Corrective Surgeries Patients

Start date: August 1, 2017
Phase: Phase 2/Phase 3
Study type: Interventional

During the surgical procedure of scoliosis correction, large surgery extent and long-lasting strong nociceptive stimulation lead to postoperative pain formation of greater intensity compared with other orthopedic interventions. In these patients, duration of postoperative symptoms is longer, and may lead to persistent pain formation due to developing neuroplastic changes in the central nervous system.

NCT ID: NCT02926404 Terminated - Spondylolisthesis Clinical Trials

UNiD Rods Register

Start date: January 2015
Phase:
Study type: Observational [Patient Registry]

Retro-prospective study allowing inclusion of patients with spinal deformities treated by patient-specific rods (UNiD). This study aims to assess performance, clinical outcomes and safety

NCT ID: NCT02873182 Not yet recruiting - Spinal Stenosis Clinical Trials

Protection of Autonomic Nervous System During Lower Spine Surgical Procedures: A Safety and Feasibility Study

Start date: August 2016
Phase: N/A
Study type: Interventional

A safety and feasibility study of free-run and stimulated corporal electromyography (EMG) to assess autonomic neural function during spinal and/or pelvic surgery in women and men.

NCT ID: NCT02761265 Recruiting - Spinal Curvatures Clinical Trials

Gait and Balance in Thoracolumbar Spinal Deformity

Start date: March 2016
Phase: N/A
Study type: Interventional

Surgical intervention may provide pain relief and improvement in function but one area of significant clinical interest is the restoration/improvement in gait and functional balance. Based on the investigators knowledge, there is limited literature on biomechanics and neuromuscular control of the lower extremities and spine as assessed by objective gait analysis and balance strategies in adult degenerative scoliosis patients, pre and post surgical intervention. The purpose of this study is to determine the impact of spinal deformity on the biomechanics and neuromuscular control of the lower and upper extremities, and also investigate the impact of surgery on these functions as evaluated by gait and balance analyses using dynamic EMG, video motion capture and force plate analysis and also to compare these patients with healthy controls to better evaluate the extent of limitations before and after surgery.

NCT ID: NCT02486107 Completed - Spinal Curvature Clinical Trials

Prospective Cohort Study of Outcome After Minimally Invasive Posterior Cervical Spine Surgery

PECD
Start date: May 2015
Phase:
Study type: Observational

In case of cervical foraminal stenosis without central stenosis, there are several options; anterior discectomy and fusion (ACDF), tubular retractor assisted micro-foraminotomy (MTPF) and posterior percutaneous cervical foraminotomy and discectomy (P-PECD). P-PECD is a modern technique and there was no RCT with MTPF, although P-PECD showed not inferior result to ACDF. Nowadays MTPF and P-PECD are minimally invasive surgical techniques, but there was no comparative study. The primary object of the study is to compare radiological outcome (segment angle) after MTPF or P-PECD.

NCT ID: NCT02424058 Recruiting - Neck Pain Clinical Trials

The Investigation of Thoracic Spinal Curvature and Mobility in Subjects With and Without Neck Pain: Cut-off Points

Start date: July 2014
Phase: N/A
Study type: Observational

The purpose of this study is to investigate the sagittal thoracic spinal curvature and mobility in subjects with and without chronic neck pain, cut-off points and pain relationship

NCT ID: NCT02390817 Completed - Spinal Curvatures Clinical Trials

Effect of Sugammadex for Muscle Motor Response and Awareness in Intraoperative Wakeup

Start date: March 2015
Phase: Phase 4
Study type: Interventional

The study will be performed to evaluate motor response and awareness with using sugammadex during wakeup procedure in spine surgery. The investigator's goal is to investigate the effect of sugammadex on the state of consciousness and motor-somatosensorial evoked potentials.