Autonomic Effects of Stimulation in SCI

Status Recruiting

Clinical Trial Summary

Clinical Trial Description

This study aims to determine the effects of transcutaneous spinal cord stimulation to increase blood pressure and use that device to increase exercise endurance time and heart rate recovery during arm cycle ergometry. In addition, the investigators will see if the stimulation helps regulate body temperature when in a cool environment. The study will consist of 7 visits, that will be between 3-4 hours in duration, separated by no less than 3 days. Visit 1 will consist of determining baseline autonomic function and screening visit. The participant will undergo a sit up set to determine hypotension and orthostatic hypotension and complete a couple surveys. Visits 2 and 3 will determine which site the stimulation parameters should be on the spine, either T7-T8 or T11-12. The site that increases seated systolic blood pressure will be used for the rest of the study. Visits 4 and 5 will consists of putting the electrode at the optimal spot on the spine and completing a submaximal arm ergometry exercise and the other visit will be a sham visit. Visits 6 and 7 will consist of assessing core temperature when in a cool environment with the stimulator on and off. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05664646
Study type	Interventional
Source	VA Office of Research and Development
Contact	Jill Wecht, EdD
Phone	(718) 584-9000
Email	jm.wecht@va.gov
Status	Recruiting
Phase	N/A
Start date	July 24, 2023
Completion date	July 30, 2026

View Details

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