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RAAS and Arterial Stiffness in SCI

Spinal Cord Injury Clinical Trial

Official title:
Orthostatic Blood Pressure and Arterial Stiffness in Persons With SCI: The Effect of RAAS System

Clinical Trial Summary

The study is examining differences in central arterial stiffness, orthostatic changes in blood pressure, norepinephrine, and plasma renin in individuals with spinal cord injury compared with age-matched uninjured controls.

Clinical Trial Description

The study is examining differences in central arterial stiffness, orthostatic changes in blood pressure, norepinephrine, and plasma renin in individuals with spinal cord injury compared with age-matched uninjured controls. Arterial stiffness and blood pressure will be collected in the laying down position. A blood sample of norepinephrine and plasma renin will also be collected. The participant will tilt to 30, 45 and 60 degrees for 10 minutes at each angel. Blood pressure and heart rate will be monitored at each angle. Another blood sample of renin and norepinephrine will be collected at the end of 10 minutes at 60 degrees. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04510974
Study type Observational
Source James J. Peters Veterans Affairs Medical Center
Contact
Status Active, not recruiting
Phase
Start date June 30, 2018
Completion date December 1, 2020
View Details
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