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Safety Study of Local Administration of Autologous Bone Marrow Stromal Cells in Chronic Paraplegia — CME-LEM1  

Spinal Cord Injury Clinical Trial

Official title:
Phase I Pilot Study to Evaluate the Security of Local Administration of Autologous Stem Cells Obtained From the Bone Marrow Stroma, in Traumatic Injuries of the Spinal Cord

Clinical Trial Summary

The purpose of this study is to confirm the security, and detect the effect of the local administration in damaged nervous tissue, of autologous bone marrow stromal cells.

Clinical Trial Description

It is a clinical trial phase I, single center, non-randomized, uncontrolled, open prospective follow-up of a cohort of patients with chronic spinal cord injury (SCI) who were treated with autologous stromal cells of the bone marrow administrated locally (subarachnoid and intramedullar) by intrathecal microinjection and three months later, by lumbar subarachnoid administration. The minimum follow-up duration for each patient is 12 months after the first administration, or until death, if it occurs it before. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01909154
Study type Interventional
Source Puerta de Hierro University Hospital
Contact
Status Completed
Phase Phase 1
Start date March 2013
Completion date March 2015
View Details
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