Spinal Cord Injury Clinical Trial
Official title:
Prevention of Orthostatic Hypotension With Electric Stimulation in Persons With Acute SCI
Background:
The presence of orthostatic hypotension (OH) as a consequence of blood volume redistribution
during verticalisation in persons with spinal cord injury (SCI) is a common condition.
Aims:
To investigate the impact of three different types of electric stimulation (ES) (ES of the
abdominal muscles versus ES of lower limb muscles versus simultaneously ES of abdominal and
lower limb muscles versus control) on blood pressure stabilization and
verticalisation-degrees between 0° and 70°. The hypothesis is, that the ES-induced
contractions of the muscles cause a stabilisation respectively an increase of the blood
pressure during the tilt-table test.
Subjects:
20 Women and men, at least 18 years of age, following an acute and traumatic SCI, with a
lesion level above T6, an American Spinal Injury Association (AIS) Impairment Scale A,B or C
and a diagnosis of OH (by tilt table test) were eligible for the study.
Methods:
Each patient underwent randomly three different types of ES sessions while being positioned
on a tilt-table. The following sessions were planned:
A) ES of the abdominal muscles B) ES of the lower limb muscles C) Combination of A and B D)
Control session (=diagnostic session)
Study type: Intervention Design: Prospective interventional study
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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