Spinal Cord Injury Clinical Trial
Official title:
A Pilot Study to Evaluate the Feasibility of Platelet-Rich Plasma Therapy as a Treatment for Chronic Shoulder Pain in Persons With Spinal Cord Injury
Shoulder pain is common in persons with spinal cord injury (SCI). It is most often caused by
overuse injuries to the muscles and tendons that can occur during wheelchair propulsion,
transfers, and other activities of daily living. Normally, shoulder pain resolves with
conservative treatments such non-steroidal anti-inflammatory drugs (e.g. aspirin, ibuprofen,
naproxen, etc.) and physical therapy. However, when these treatments fail, shoulder surgery
may be the only option.
Platelet Rich Plasma therapy, or PRP, is a treatment option for non-healing muscle and
tendon injuries such as those that cause shoulder pain in persons with SCI. Using one's own
blood, cells within the blood called "platelets" are concentrated and then re-injected into
the muscle and tendon of the shoulder. These platelets release substances known as "growth
factors" that lead to tissue healing. By concentrating the platelets we increase the growth
factors up to eight times which will promote the healing of tendons. PRP therapy has shown
promise in treating tendon and muscle injuries in able-bodied persons; however, its
effectiveness in persons with SCI is unknown. The purpose of this study is to explore the
feasibility, safety, and efficacy of PRP therapy for chronic shoulder pain in persons with
SCI. The human body has a remarkable ability to heal itself and we hypothesize that
re-injecting concentrated platelets will facilitate the natural healing process and will
reduce shoulder pain in persons with SCI.
n/a
Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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