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Spinal Cord Injury clinical trials

View clinical trials related to Spinal Cord Injury.

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NCT ID: NCT01498991 Terminated - Spinal Cord Injury Clinical Trials

Spinal Cord Injury Leg Rehabilitation

AMES
Start date: November 2011
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to determine if individuals with incomplete spinal cord injury (SCI) who remain unable to walk normally 1 year after their SCIs are able to sense and move the affected legs better after 10-13 weeks of treatment with a new robotic therapy device. The hypothesis is that using the AMES device on the legs of chronic subjects with incomplete SCI will result in improved strength, sensation in the legs, and improved functional gait in the treated limbs.

NCT ID: NCT01491789 Completed - Spinal Cord Injury Clinical Trials

Virtual Sailing Simulator in Individuals With Spinal Cord Injury

VSail
Start date: May 2011
Phase: N/A
Study type: Interventional

The research is being done to look at the benefits of a recreational and therapeutic program for people with spinal cord injury using the VSail-Access sailing simulator.

NCT ID: NCT01485458 Completed - Spinal Cord Injury Clinical Trials

Optimal Treatment for Spinal Cord Injury Associated With Cervical Canal Stenosis (OSCIS) Study

OSCIS
Start date: December 2011
Phase: N/A
Study type: Interventional

Controversy exists regarding the optimal management of acute traumatic cervical spinal cord injury (SCI), especially those without bone injury. Although surgical decompression is often performed in SCI patients with cervical canal stenosis, efficacy and timing of surgery continues to be a subject of intense debate. In this randomized controlled trial, the investigators compare two strategies: early surgery within 24 hours after admission and delayed surgery following at least 2 weeks of conservative treatment. The purpose of this study is to examine whether early surgery would result in greater improvement in motor function as compared with delayed surgery.

NCT ID: NCT01484184 Completed - Spinal Cord Injury Clinical Trials

Study to Assess Safety, Tolerability and MTD of a Central Pattern Generator-activating Tritherapy (SPINALON) in Patients With Chronic Spinal Cord Injury

Start date: July 2013
Phase: Phase 1/Phase 2
Study type: Interventional

As a first-in-class (Central Pattern Generator or CPG activator) approach, this tritherapy candidate called SPINALON has been identified and is currently under development for its capacity to temporarily induce episodes of involuntary locomotor movements. The primary objective of this Phase I/IIa study is to assess safety and tolerability of a single escalating dose of SPINALON (levodopa + carbidopa + buspirone) in chronic spinal cord-injured patients. As a secondary objective, preliminary evidence of efficacy will also be sought.

NCT ID: NCT01479777 Completed - Spinal Cord Injury Clinical Trials

Functional Electrical Stimulation (FES) Driven Stepping in Individuals With Spinal Cord Injury

Start date: April 2011
Phase: Phase 1/Phase 2
Study type: Interventional

The research is being done to find out if Functional Electrical Stimulation (FES) stepping can improve the function of people with spinal cord injury that paralyzes.

NCT ID: NCT01477736 Completed - Spinal Cord Injury Clinical Trials

A Comparison Study of Oxybutynin and Botulinum Toxin for Neurogenic Detrusor Overactivity

Start date: January 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the effects of oral oxybutynin and intradetrusor injections of botulinum toxin type A on urodynamic parameters and quality of life in patients with neurogenic detrusor overactivity following spinal cord injury.

NCT ID: NCT01477502 Completed - Spinal Cord Injury Clinical Trials

Clinical Value of Homeopathic Prophylaxis of Recurrent Urinary Tract Infections in Persons With Spinal Cord Injury

Start date: November 2011
Phase: N/A
Study type: Interventional

recurrent symptomatic urinary tracts infections (UTI) in persons with spinal cord injury are a frequent problem, leading to significant morbidity and to a decreased quality of life. - until today, there is no effective prophylaxis for UTI for patients with spinal cord injury. - homeopathy has been shown to be an effective treatment option in several chronic diseases - study hypothesis: the addition of homeopathic assessment and treatment to a standard prevention strategy for recurrent UTI will significantly reduce the number of symptomatic UTI per year in this group of patients compared to standard prevention alone

NCT ID: NCT01474148 Recruiting - Spinal Cord Injury Clinical Trials

A Neuroprosthesis for Seated Posture and Balance

Trunk Protocol
Start date: November 30, 2011
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate a surgically implanted functional electrical stimulation (FES) system to facilitate stability of the trunk and hips. FES involves applying small electric currents to the nerves, which cause the muscles to contract. This study evaluates how stabilizing and stiffening the trunk with FES can change the way spinal cord injured volunteers sit, breathe, reach, push a wheelchair, or roll in bed.

NCT ID: NCT01471613 Completed - Spinal Cord Injury Clinical Trials

Lithium, Cord Blood Cells and the Combination in the Treatment of Acute & Sub-acute Spinal Cord Injury

Start date: September 2011
Phase: Phase 1/Phase 2
Study type: Interventional

The trial is to investigate the safety and efficacy of oral lithium, intraspinal umbilical cord blood mononuclear cell transplant, and the combination in the treatment of acute and subacute spinal cord injury

NCT ID: NCT01467869 Recruiting - Spinal Cord Injury Clinical Trials

Male Fertility Program

MFP
Start date: January 1991
Phase:
Study type: Observational

Following spinal cord injury, most men are infertile and require medical assistance to father children. The conditions that contribute to their infertility are erectile dysfunction, ejaculatory dysfunction, and semen abnormalities. The Miami Project Male Fertility Program is a research study designed to understand and improve impairments to male fertility resulting from spinal cord injury.