Strength Training With Eccentric Arm-cranking in Para-athletes

Spinal Cord Injuries Clinical Trial

— KREHA-ParAth  

Official title:

Strength Training With Eccentric Arm-cranking in Para-athletes

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05777941
• Other study ID #: 2022-06
• Status: Recruiting
• Phase: N/A
• Start date: May 1, 2022
• Est. completion date: May 30, 2024

Study information

• Verified date: March 2023
• Source: Swiss Paraplegic Research, Nottwil
• Contact: Fabian Ammann, MSc
• Phone: +4941419396624
• Email: fabian.ammann[@]sportmedizin-nottwil.ch
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The new training device, the eccentric arm-crank, will be examined for its training effects in athletes with a spinal cord injury (SCI) by this project. That the training device can be used in patients with paraplegia in the future, the so-called "testing of the applicability of this concept" will be carried out during this study. Fourteen volunteer, healthy athletes with SCI are first tested for their upper body performance, followed by a training phase over 20 trainings and at the end the performance data is collected again. The training intensity and duration is continuously increased during the training phase.

Description:

At the beginning, the study design includes a familiarisation appointment with performance tests and training on the eccentric arm-crank device (KREHA). At least one week later, the first test sequence including a maximum strength test (bench press) and a test to determine the anaerobic performance (Wingate test) is conducted. The second test sequence takes place one to three days later. This includes a handgrip strength test, an aerobic endurance test (ramp test on the arm crank ergometer with ergospirometry) and a further familiarisation training on the KREHA. The training phase starts within two weeks after the pre-tests have been completed. There are two to a maximum of three trainings per week. These take 30 to 45 minutes and take place on the KREHA device under the supervision of the study staff. The training phase lasts a maximum of twelve weeks (20 training sessions). The first test sequence is repeated five to eight days after the last workout. The second test sequence takes place at the same time interval as in the pre-tests.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 14
• Est. completion date: May 30, 2024
• Est. primary completion date: December 31, 2023
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 50 Years

Eligibility

Inclusion Criteria:

• male or female with traumatic or disease-related SCI

• age between 18 and 50 years

• experience in strength training

• Squad status or at least 4h per week training

• Biceps/triceps function

• healthy(study physician)

• adequately informed and confirmed per signature

Exclusion Criteria:

• findings during anamnesis of study physician

• pregnancy

Related Conditions & MeSH terms

• Spinal Cord Injuries

Intervention

Other:
• eccentric arm-cranking training
Over the twenty training sessions, able-bodied participants will exercise on the KREHA device. An arm-crank has to be decelerated, which will be rotated by a prematurely defined revolution rate and training duration. During this intervention a certain power has to be applied. During the whole time of training a continous progression in power and training duration is applied.

Locations

Country	Name	City	State
Switzerland	Swiss Paraplegic Centre	Nottwil	Lucerne

Sponsors (1)

Lead Sponsor	Collaborator
Swiss Paraplegic Research, Nottwil

Country where clinical trial is conducted

Switzerland, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Upper body Performance	Peak Power - maximal reached power, generated during the 30sec Wingate arm-crank test	through study completion, an average of 20 weeks
Secondary	Endurance Oxygen consumption	VO2peak [ml/min/kg] - Basic Endurance test (Ergospirometry, arm-crank)	through study completion, an average of 20 weeks
Secondary	Maximal Workload	Wmax [W] - Basic Endurance test (Ergospirometry, arm-crank)	through study completion, an average of 20 weeks
Secondary	Upper body Mean Power	Mean Power [W] - Wingate Test (arm-crank)	through study completion, an average of 20 weeks
Secondary	Upper body Power - Time to Peak	Time to Peak [s] - Wingate Test (arm-crank)	through study completion, an average of 20 weeks
Secondary	Upper body Fatigue Index	Fatigue Index [%]- Wingate Test (arm-crank)	through study completion, an average of 20 weeks
Secondary	Upper body Fatigue Slope	Fatigue Slope [W/s] - Wingate Test (arm-crank)	through study completion, an average of 20 weeks
Secondary	1RM bench press	One Repetition Maximum (1RM) [kg]- bench press	through study completion, an average of 20 weeks
Secondary	Grip Strength	Maximal Force that can be generated by pressing hand towards a fist [N]	through study completion, an average of 20 weeks
Secondary	Upper Arm Circumference	Circumference of the upper arm is measured with measuring tape	through study completion, an average of 20 weeks
Secondary	Lower Arm Circumference	Circumference of the lower arm is measured with measuring tape	through study completion, an average of 20 weeks