Clinical Trials Logo

Spinal Cord Injuries clinical trials

View clinical trials related to Spinal Cord Injuries.

Filter by:

NCT ID: NCT05068648 Recruiting - Clinical trials for Spinal Cord Injuries

Wheelchair Backs That Support the Spinal Curves

Start date: December 1, 2021
Phase: N/A
Study type: Interventional

The overall objective of this fully powered clinical trial is to investigate if using a solid backrest on a manual wheelchair (MWC) will improve postural alignment, function and wheelchair mobility, as compared with an upholstery backrest, and to explore the impact of overall back height, contour, and seat gap when using a solid backrest in individuals with spinal cord injury (SCI).

NCT ID: NCT05044923 Recruiting - Clinical trials for Spinal Cord Injuries

Restoring Hemodynamic Stability Using Targeted Epidural Spinal Stimulation Following Spinal Cord Injury

HEMO
Start date: December 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to stimulate the circuits in the spinal cord that are directly responsible for hemodynamic control to restore hemodynamic stability in participants with chronic cervical or high-thoracic spinal cord injury. The ultimate objective of this study is to provide preliminary safety and efficacy measures on the ability of the hemodynamic Targeted Epidural Spinal Stimulation (TESS) to ensure the long-term management of hemodynamic instability and reduce the incidence and severity of orthostatic hypotension and autonomic dysreflexia episodes in individuals with chronic cervical or high-thoracic spinal cord injury. In addition, the long-term safety and efficacy of TESS on cardiovascular health, respiratory function, and quality of life in participants with chronic spinal cord injury will be evaluated.

NCT ID: NCT05041322 Recruiting - Clinical trials for Spinal Cord Injuries

Improving Ventilatory Capacity in Those With Chronic High Level SCI

Start date: November 29, 2020
Phase: Phase 2
Study type: Interventional

The purpose of this study is to find out if taking the drug Buspar will increase breathing capacity in individuals with spinal cord injuries.

NCT ID: NCT05024487 Recruiting - Clinical trials for Spinal Cord Injuries

Prevention of Complications Due to Autonomic Dysreflexia in SCI Individuals

Start date: January 1, 2023
Phase: N/A
Study type: Interventional

Autonomic dysreflexia (AD) is a syndrome of unbalanced response of the sympathetic system to noxious stimuli below the level of spinal cord injury (SCI), characterized by paroxysmal hypertension. Mostly, it is combined with symptoms such as pounding headache, slowed heart rate, and upper body flushing, but it can also be asymptomatic. When resulting in hypertensive crisis, it can be life-threatening and result in seizures, cardiac arrest, retinal or subarachnoid hemorrhages, stroke, and even death. The aim of this study is to determine the risk level of vascular complications in SCI people by correlating the clinical symptoms with their individual perception during AD triggered below the level of injury.

NCT ID: NCT05005026 Recruiting - Clinical trials for Spinal Cord Injuries

Virtual Walking Intervention for Neuropathic Pain in Spinal Cord Injury

VRWalk
Start date: November 23, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if playing a virtual reality walking game can help improve neuropathic pain in adults with chronic spinal cord injury.

NCT ID: NCT04994886 Recruiting - Clinical trials for Spinal Cord Injuries

Restoring Hemodynamic Stability Using Targeted Epidural Spinal Stimulation Following Spinal Cord Injury

STIMO HEMO
Start date: June 8, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to stimulate the circuits in the spinal cord that are directly responsible for hemodynamic control to restore hemodynamic stability in patients with chronic cervical or high-thoracic spinal cord injury. The ultimate objective of this feasibility study is to provide preliminary safety and efficacy measures on the ability of the hemodynamic Targeted Epidural Spinal Stimulation (TESS) to ensure the long-term management of hemodynamic instability and reduce the incidence and severity of orthostatic hypotension and autonomic dysreflexia episodes in humans with chronic cervical or high-thoracic spinal cord injury. In addition, the long-term safety and efficacy of TESS on cardiovascular health, respiratory function, spasticity, trunk stability and quality of life in patients with chronic spinal cord injury will be evaluated.

NCT ID: NCT04977037 Recruiting - Clinical trials for Incomplete Spinal Cord Injury

A Telerehabilitation Program for SCI

Start date: July 1, 2021
Phase: N/A
Study type: Interventional

This study evaluates a remotely supervised, home-based therapeutic program to improve upper-limb voluntary movement in adults with tetraplegia caused by incomplete spinal cord injury (iSCI).

NCT ID: NCT04973852 Recruiting - Clinical trials for Spinal Cord Injuries

High Intensity Training for Neurological Injury Using Overground Exoskeletons in Inpatient Rehabilitation

HIT Exo IP
Start date: October 6, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to see if it's possible to reach high cardiovascular intensity training parameters (exercise at a rate that elevates heart rate to the level recommended for improving strength and endurance) while walking in a wearable robotic exoskeleton. This study will also evaluate if exercising at high intensity will lead to improvement in walking ability. Participants in this study will be asked to attend 5 walking training sessions using Ekso exoskeleton. There will be two additional sessions, one before and one after the five training sessions. At these two sessions, study participants will be asked to participate in seated balance, walking speed and endurance tests and breathing assessments.

NCT ID: NCT04971408 Recruiting - Spinal Cord Injury Clinical Trials

Impact of Passive Heat on Metabolic, Inflammatory and Vascular Health in Persons With Spinal Cord Injury

SCIPHS
Start date: July 1, 2022
Phase: N/A
Study type: Interventional

SCI results in higher incidence of heart disease and diabetes and heart disease is the most common cause of death. Chronic inflammation, deleterious changes in vascular structure and impaired glucose metabolism are risk factors that contribute to both heart disease and diabetes. While exercise can help reduce these risk factors, paralysis and impaired accessibility often precludes exercise in persons with SCI. New research in able-bodied persons demonstrates passive heating decreases inflammation and improves vascular function. Similar studies in persons with SCI suggest they may also have the same health benefits however these studies only investigated the impact of short term (one episode) passive heating (as opposed to repeated bouts). Repeated bouts of heat exposure will likely be required to impact chronic inflammation, but this has never been tested in persons with SCI. This study will test the impact of repeated bouts (3x/week) of passive heat stress over a longer term (8 weeks) on inflammation, metabolism and vascular function.

NCT ID: NCT04969042 Recruiting - Clinical trials for Spinal Cord Injuries

Closed-loop Functional Spinal Cord Stimulation in Patients With Spinal Cord Injury

COFUN
Start date: August 1, 2021
Phase: Phase 1
Study type: Interventional

The purpose of this experiment is to evaluate the efficacy of Closed-loop Functional Spinal Cord Stimulation on Walking Rehabilitation in Patients after Spinal Cord Injury