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Spinal Anesthesia clinical trials

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NCT ID: NCT05535036 Completed - Postoperative Pain Clinical Trials

Intravenous Dexamethasone Effectiveness in Post Caesarean Section Analgesia

Start date: February 10, 2020
Phase: N/A
Study type: Interventional

The management of postpartum pain is essential to ensure early rehabilitation for parturients. Intravenous dexamethasone has a potent analgesic action when used in the context of general anesthesia. Nevertheless, it remains poorly studied in combination with spinal anesthesia (SA). The aim of this study was to assess the analgesic effect of intravenous dexamethasone after caesarean section under SA. Methods: We conducted a prospective, randomized, double-blinded study including 84 ASA II-III parturient at term who were proposed for caesarean section under SA. Parturient were randomized into two groups: Dexamethasone group (DG) who received 8mg of intravenous dexamethasone (2ml) immediately after SA and placebo group (PG) who received 2ml of isotonic saline. The analgesic protocol was standardized and we opted for Tramadol as rescue analgesic. The main outcome is the use of Tramadol in the first 24 hours postpartum..

NCT ID: NCT05444803 Completed - Analgesia Clinical Trials

Femoral Nerve Block vs Peri-capsular Nerve Group Block for Hip Fracture Analgesia

Start date: July 6, 2022
Phase: N/A
Study type: Interventional

The purpose of the study is to compare the analgesic efficacy of femoral nerve block and peri-capsular nerve group block administered before spinal anesthesia for positioning to spinal anaesthesia in patients undergoing surgery for hip fracture and to evaluate the efficacy for postoperative analgesia

NCT ID: NCT05317572 Completed - Cesarean Section Clinical Trials

Comparison of Three Different Doses of Intrathecal Morphine for Analgesia After Cesarean Section

Start date: October 1, 2017
Phase: N/A
Study type: Interventional

In our study, It was aimed to determine the dose of morphine that provides the most effective analgesia with the least incidence of side effects in the postoperative period.

NCT ID: NCT05305248 Completed - Sedation Clinical Trials

Sedation With Remimazolam During Spinal Anesthesia

Start date: April 19, 2022
Phase: N/A
Study type: Interventional

Remimazolam is a benzodiazepine-binding site antagonist of the GABA receptor, metabolized by esterases, and exhibits a stable context-sensitive half-life of 6-7 minutes. Remimazolam has a high clearance rate and a small volume of distribution in the pharmacokinetic model. The US FDA has approved sedation for surgery. Although there have been studies on the use of remimazolam as a sedative for procedures such as endoscopy, there have been no reports of the use of remimazolam in spinal anesthesia. The purpose of this study is to compare and analyze the hemodynamics and recovery profile of patients undergoing surgery under spinal anesthesia by maintaining sedation with dexmedetomidine or remimazolam.

NCT ID: NCT04806997 Completed - Spinal Anesthesia Clinical Trials

Changes in the Microvascular Reactivity on Leg During Spinal Anesthesia

Start date: December 29, 2016
Phase:
Study type: Observational

Anesthesia alters microcirculation and tissue oxygen saturation (StO2). We sought to examine changes in StO2 using near-infrared spectroscopy and a vascular occlusion test (VOT) during spinal anesthesia. This prospective observational study was included 51 patients without comorbidities who underwent elective surgery under spinal anesthesia. We measured the StO2 in the lower extremity during VOT before and after intrathecal injection.

NCT ID: NCT04778189 Completed - Spinal Anesthesia Clinical Trials

Effect of Intravenous Dexamethasone on Duration of Hyperbaric Bupivacaine Spinal Anesthesia in Lower Abdominal Surgery

Start date: December 1, 2021
Phase: Phase 2
Study type: Interventional

The use of dexamethasone, administered either systemically or perineurally, as an adjunct to peripheral or neuraxial regional blocks, is currently one of the hottest topics in the field of regional anesthesia.

NCT ID: NCT04485650 Completed - Anxiety Clinical Trials

Effect of Music in Intraoperative Period

Start date: February 24, 2017
Phase: N/A
Study type: Interventional

Background and Aims: Music therapy has a wide range of uses in health care practice. The aim of this study was to investigate the effects of intraoperative music played during spinal anesthesia operation on the patients' intraoperative vital signs, postoperative pain, and anxiety status. Methods: The study was performed in an operating room with a total of 90 patients, of whom 30 were in the music group, 30 were in the control group and 30 were in the sedated group. The ethics committee's approval, institutional permission, and the study participants' written informed consent were obtained. Data were collected using patient information and intraoperative observation form for vital signs as well as through the Visual Analog Scale and State Anxiety Scale. Preoperative and postoperative anxiety, the intraoperative and postoperative vital signs and postoperative pain and anxiety of all groups were analyzed.

NCT ID: NCT04438811 Completed - Spinal Anesthesia Clinical Trials

Task-based Credentialing for Medical Officers in Spinal Anesthesia

Start date: March 1, 2019
Phase: N/A
Study type: Interventional

Test the safety and effectiveness of training medical officers in the provision of spinal anesthesia in a rural hospital context using a non-inferiority randomized trial. The safety and effectiveness of the MOs will be evaluated through a non-inferiority trial in which patients are randomized to care by a trained MO or an anesthesiologist. The primary outcomes are safety (adherence to adapted anesthesia safety checklist- see supporting documents "Adapted Anesthesia Safety Checklist") and effectiveness (adequate analgesia) of spinal anesthesia.

NCT ID: NCT04432675 Completed - Cesarean Section Clinical Trials

Effects of Crystal Solution and Colloid Solution on Mother and Fetus

Start date: January 30, 2022
Phase: Phase 4
Study type: Interventional

Comparison of the effects of crystal solution (lactic acid Ringer's solution) and colloid solution (hydroxyethyl starch) on mother and fetus after cesarean section

NCT ID: NCT04307290 Completed - Spinal Anesthesia Clinical Trials

Dexmedetomidine on Tourniquet Induced -Systemic Effects

Start date: February 3, 2020
Phase: Phase 4
Study type: Interventional

Eighty patients were randomly assigned to either control (CON) or dexmedetomidine (DEX) group. DEX group received a loading dose of 0.5 µg/ kg of intravenous dexmedetomidine over 10 minutes, followed by a continuous infusion of 0.5 µg/kg/h until completion of the surgery. CON group received the same calculated volume of normal saline. Pain outcomes, metabolic and coagulative changes after tourniquet application, and after tourniquet release were investigated.