Sperm DNA Fragmentation Clinical Trial
Official title:
Effect of Different Sperm Processing Methods ( Swim up, Zeta, Sperm Gradient Centrifugation ) in ICSI Outcome. "A Sperm DNA Perspective"
A total 180 semen samples from couples diagnosed with unexplained infertility were SDF index tested , then total 120 semen samples of patients' husbands with abnormal SDF index were randomly divided and then processed by swim up, sperm gradient centrifugation and Zeta methods. SDF and ICSI outcomes are monitored after semen processing.
A total 180 semen samples from couples diagnosed with unexplained infertility were SDF index tested , then total 120 semen samples of patients' husbands with abnormal SDF index were randomly divided and then processed by swim up (G1/ n=40), sperm gradient centrifugation (G2/ n=40) and Zeta (G3/ n=40) methods. SDF test was assessed by Halosperm kit, whereas sperm morphology was assessed by spermac stain according to strict criteria. Fertilization, division, blastulation, implantation and pregnancy rates will be tabulated and statistically tested. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT03527043 -
Impact of Escitalopram on Sperm DNA Fragmentation
|
Phase 2 | |
Completed |
NCT03085433 -
Sperm Selection by Microfluidic Separation Improves Embryo Quality
|
N/A | |
Completed |
NCT06231589 -
PGT-A Evaluates Advanced Sperm Selection in Embryos From High Teratozoospermia Males
|
N/A | |
Completed |
NCT03398317 -
Sperm Selection by Either PICSI or MACS in Cases With Abnormal Sperm DNA Fragmentation Index for ICSI
|
N/A | |
Recruiting |
NCT05508217 -
Impact of Telomere Biology and Sperm DNA Fragmentation on Embryonic Development
|
||
Completed |
NCT05494216 -
Advanced Sperm Selection Techniques and Their Contribution to Blastocyst Euploidy Rates
|
N/A |