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Clinical Trial Summary

Our aim is to evaluate the potential of a new laboratory method that measure sperm capacitation to predict fertilization of oocytes in patients that undergo IVF treatments


Clinical Trial Description

Capacitation is a physiologic process in which the sperm acquire the potential to fertilize oocytes. Capacitation can be measured, but the available technics are expensive, inaccurate and complex. A new method to evaluate sperm capacitation was developed in Bar Ilan University, Israel. We intend to measure the capacitation of semen that is used for fertilizing human oocytes in patients treated at the IVF unit at Assaf Harofeh Medical Center.By this, to evaluate the potential of the new method to predict human oocyte fertilization.If the method will be found valuable, it will enable to develop new drugs/methods that may improve sperm capacitation and by this to improve oocyte fertilization leading to more embryos, pregnancies and deliveries. ;


Study Design

Time Perspective: Prospective


Related Conditions & MeSH terms


NCT number NCT00731159
Study type Observational
Source Assaf-Harofeh Medical Center
Contact arieh raziel, prof
Phone 97289779005
Email araziel@asaf.health.gov.il
Status Recruiting
Phase N/A
Start date July 2008
Completion date July 2009

See also
  Status Clinical Trial Phase
Recruiting NCT04962100 - Capacitation-associated Protein Tyrosine Phosphorylation as a Possible Biomarker of Sperm Selection N/A