Specific Language Impairment Clinical Trial
Official title:
Specific Language Impairment (SLI) in Children May Caused by Epileptic Brain Activity
Verified date | October 2019 |
Source | Mansoura University Hospital |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
The objective of this study was to find if there is a possible association and the impact of epilepsy and epileptiform activity in children with SLI.
Status | Completed |
Enrollment | 160 |
Est. completion date | March 1, 2019 |
Est. primary completion date | January 1, 2019 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 3 Years to 6 Years |
Eligibility |
Inclusion Criteria: - 80 children were suffering from specific language impairment - 80 healthy children with age and sex match control group. Exclusion Criteria: - Previous history of perinatal hypoxic-ischemic damage - meningitis or encephalitis - motor weakness - hearing disorders - IQ below seventy - CP, social deprivation - autism and - psychiatric disorders . |
Country | Name | City | State |
---|---|---|---|
Egypt | Mansoura University Hospital | Mansoura | Dakahlia |
Lead Sponsor | Collaborator |
---|---|
Mansoura University Hospital |
Egypt,
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Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Other | Intelligence quotient (IQ) | An intelligence quotient (IQ) is a total score derived from several standardized tests designed to assess human intelligence. Historically, IQ is a score obtained by dividing a person's mental age score, obtained by administering an intelligence test, by the person's chronological age, both expressed in terms of years and months. The resulting fraction is multiplied by 100 to obtain the IQ score. When current IQ tests were developed, the median raw score of the norming sample is defined as IQ 100 and scores each standard deviation (SD) up or down are defined as 15 IQ points greater or less. |
24-72 hours | |
Other | social age | Evaluation of social age: using the Vineland Social Maturity Scale . VSMS was used along with a cognitive assessment to help make a diagnosis of mental retardation or intellectual disability. It has also been used extensively to assess the development of activities of everyday life. | 24-48 hours | |
Other | cognitive age | Evaluation of cognitive age (mental age): using the Stanford Binet Intelligence Scale. The Stanford-Binet test is a examination meant to gauge intelligence through five factors of cognitive ability. These five factors include fluid reasoning, knowledge, quantitative reasoning, visual-spatial processing and working memory. Both verbal and nonverbal responses are measured. | 24-48 hours | |
Other | language assessment | Language evaluation: by Comprehensive Arabic Language Test (CALT). The CALT was constructed by the members of the Department of Phoniatrics at Alexandria Main University Hospital, Egypt, to form a detailed comprehensive assessment battery for Arabic language and test its reliability and validity to use it in the early detection of subtle changes in the various components of language in cases of language impaired children. | 24-72 hours | |
Primary | EEGs finding | EEGs finding were defined according to the followings "Normal: within the range of frequency and amplitude distribution." "Epileptiform: Describes transient background activity with a characteristic spikes, sharp waves, spike-slow wave or sharp-slow wave complexes of focal or generalized distribution". "Abnormal non-epileptiform: deviations from normal in terms of background frequency patterns, usually in the form of excessive slow activity". |
24-48 hours |
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