Spastic Clinical Trial
Official title:
To Estimate the Efficacy of Botulinum Toxin A Injection Combing With Exoskeleton Robotic Assisted Gait Training in Stroke Patients With Spastic Stiff Knee Gait: Motor Function Performance and Neurophysiological Evaluation
The purpose of this project is to examine and compare the immediate and long-term effects of combined Botulinum toxin type A(BoNT-A) injection with exoskeleton Robotic assisted gait training (RABT) in patients with post-stroke stiff-knee gait.
The aim of the study is to evaluate the effects of BoNT-A combining with overground exoskeleton robot for patients with post-stroke stiff-knee gait. Stiff-knee gait (SKG) is a common gait pattern in patients after stroke, characterized by limited knee flexion (KF) during the swing phase of walking. Botulinum toxin A (BoNT-A) injection in rectus femoris muscle is considered the gold standard procedure to treat SKG. Patients with this gait pattern would reduce walking speed, cause toe dragging, compromise the stability of walking, increase risk of falling, and interfere with daily activities. This randomized controlled trial will contribute to the accelerated refinement and development of efficient and effective treatment programs for patients with post-stroke spastic stiff knee gait. The Robot-assisted gait training (RAGT) has the potential to be an optimal adjunctive therapy following BoNT-A treatment. Combinations of BoNT-A and rehabilitation training are suggested to optimize the treatment effect for spasticity related disabilities. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT03908801 -
Evaluation of Specialized Water Dance Intervention
|
N/A | |
Completed |
NCT05596513 -
Motor Learning Approaches From Working on a Vertical Surface in Hemiplegic Children's Upper Limb Motor Skills
|
N/A | |
Recruiting |
NCT06214975 -
EXOPULSE Mollii Suit, Motor Function & Stroke (EXOSTROKE 2)
|
N/A | |
Completed |
NCT05636241 -
Whole Body Vibration in Children With Cerebral Palsy
|
N/A | |
Recruiting |
NCT05912595 -
EXOPULSE Mollii Suit, Spasticity, Muscular Oxygenation & Multiple Sclerosis (ENNOX 2)
|
N/A | |
Recruiting |
NCT05857280 -
EXOPULSE Mollii Suit, Motor Function & Multiple Sclerosis (EXOSEP 2)
|
N/A | |
Completed |
NCT05231538 -
Neurodevelopmental Therapy for Spastic Cerebral Palsy
|
N/A | |
Completed |
NCT04859673 -
Influence of Radial Extracorpeal Shock Wave in Hemiplegic Shoulder Patients
|
N/A | |
Recruiting |
NCT05648422 -
Effect of the Nutritional Support System on Neuromotor Alterations in Patients With Cerebral Palsy
|
N/A | |
Not yet recruiting |
NCT03751306 -
Aerobic Exercise and Transcranial Low Laser Therapy in Patients With Central Nervous System Injury
|
N/A | |
Completed |
NCT04770363 -
Comparison Between Unihemispheric and Bihemispheric TCDS in Subacute Ischemic Stroke Patients
|
N/A | |
Completed |
NCT05022095 -
"Validated Language Transfer of the Spinal Cord Injury-Spasticity Evaluation Tool to German Language"
|
||
Completed |
NCT04826900 -
Wearable Robotic System and Robotic Mirror Therapy in Spastic Hemiplegia Post Botulinum Toxin Injection
|
N/A | |
Completed |
NCT03440632 -
Functional Electrical Stimulation During Walking in Cerebral Palsy
|
N/A |