Solid Tumour Clinical Trial
Official title:
A Phase 1, Pharmacokinetically-Guided, Dose Escalation Study to Assess the Safety and Tolerability of Dexanabinol in Patients With Advanced Solid Tumours
This study is a trial of Dexanabinol in patients with advanced solid tumours. The purposes
of this protocol are to study different doses of the study drug to determine the maximum
safe dose and to further understand the safety of the study drug; to understand what the
body does to the study drug; to understand what the study drug does to the body and to
measure any reduction in size of patients' cancer tumour(s).
Dexanabinol is a synthetic nonpsychotropic cannabinoid derivative which was initially
developed as a neuroprotective agent due to its antiinflammatory activity. Because of its
method of action however it is thought that it may have the effect of destroying cancer
cells by reducing the level of control on networks that prevent cancer cells dying.
n/a
Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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