Solid Tumor Clinical Trial
Official title:
A Phase II Study of BAY 1000394 in MCL1-Amplified, MYC-Amplified, CCNE1-Amplified Tumors
This research study is studying whether a new experimental cancer study drug BAY 1000394 will be helpful in treating solid tumor cancer with an abnormality in one of the following genes: Mcl-1, Myc or CCNE.
- This research study is a Phase II clinical trial. Phase II clinical trials test the
effectiveness of an investigational drug to learn whether the drug works in treating a
specific cancer.
- "Investigational" means that the drug is still being studied and that research doctors
are trying to find out more about it-such as the safest dose to use, the side effects
it may cause, and if the drug is effective for treating different types of cancer.
- It also means that the FDA (the U.S. Food and Drug Administration) has not approved BAY
1000394 for use in participants with your type of cancer.
- The study drug is a pan-CDK inhibitor targeting the genetic defect in several tumors,
MCL1, Myc, or CCNE.
;
Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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