Clinical Trials Logo

Clinical Trial Summary

The purpose of this study is to determine the maximum tolerated dose (MTD) of lenvatinib in patients with solid tumors or lymphomas.


Clinical Trial Description

This is an open-label, non-randomized, dose escalation study. Patients will be treated with lenvatinib once daily. Each four-week treatment period will be considered to be one treatment cycle. The selection of subsequent dose levels will be performed according to an accelerated design: Although initially 3 patients per dose level will be entered, the next dose level can be opened for patient accrual after only the first patient in the previous cohort completes Cycle 1 with no drug-related toxicity greater than grade 1 (except alopecia, lymphopenia and anemia). ;


Study Design


Related Conditions & MeSH terms


NCT number NCT00121719
Study type Interventional
Source Eisai Inc.
Contact
Status Completed
Phase Phase 1
Start date July 1, 2005
Completion date March 1, 2019

See also
  Status Clinical Trial Phase
Recruiting NCT04711733 - Supportive Care Needs of Former Child, AYA Cancer Patients, and of Their Parents: Evaluation During Long-term Follow-up