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Clinical Trial Summary

A prospective study evaluating prone and supine positioning for radiation planning of spine Cyberknife radiotherapy treatment. Patients with tumours in which PTV coverage is compromised due to tumour geography, including posteriorly based lesions in the vertebral column and close proximity to organ at risk (other than the spinal cord).


Clinical Trial Description

This is a prospective, non-randomised radiotherapy planning study. Subsets of patients with specific tumour and anatomical characteristics will benefit from improved PTV prescription isodose coverage, reduced spinal cord dose, and organs at risk dose by undergoing either prone or supine setup, planning and treatment. Both prone and supine CT radiotherapy planning scans for patients undergoing spine SBRT treatment will undergo comparison of radiotherapy plans to guide recommendation of prone treatment for future patients. Patients continue to receive treatment in the proposed position as recommended y their treating physician. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05252975
Study type Interventional
Source Royal Marsden NHS Foundation Trust
Contact Merina Ahmed
Phone 02086426011
Email merina.ahmed@rmh.nhs.uk
Status Recruiting
Phase N/A
Start date July 1, 2020
Completion date April 1, 2023

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