iPeer2Peer Pediatric Thoracic Transplantation

Status Completed

Clinical Trial Summary

With the on-going presence of a chronic illness, daily immunosuppressive medications, and the need for continuous medical supervision, pediatric transplant recipients face considerable psychosocial stresses. Treatment nonadherence is a major issue in pediatric transplantation and can lead to increased rates of hospitalization, rejection episodes, graft loss and death. An online peer support mentorship program (iPeer2Peer) is proposed as one intervention that could enhance patient care management, increase treatment adherence, reduce social isolation and improve health outcomes for this highly vulnerable population. The proposed trial will determine 1) implementation outcomes of the iPeer2Peer intervention in terms of: (a) feasibility and adoption, (b) acceptability and appropriateness and (c) level of engagement with the program, and 2) effectiveness of the iPeer2Peer intervention on improving health outcomes including disease self-management skills, treatment adherence, quality of life, perceived social support, stress and coping.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Solid Organ Transplant

Clinical Trial Details

NCT number	NCT04253548
Study type	Interventional
Source	The Hospital for Sick Children
Contact
Status	Completed
Phase	N/A
Start date	May 20, 2021
Completion date	August 31, 2023

View Details

See also
Status	Clinical Trial	Phase
Terminated	`NCT03950414` - A Dose-Escalation Study Evaluating Safety and Tolerability of Viral-Specific T Cells Against CMV in Adult Solid Organ Transplant Recipients	Phase 1
Recruiting	`NCT05663463` - Seasonal Influenza Vaccine High Dose Boosting in Solid Organ Transplant Recipients	N/A
Completed	`NCT05124509` - Immune Response to Third Dose of COVID-19 Vaccine in Solid Organ Transplant
Completed	`NCT05121142` - Study of Ruxolitinib for Acute and Chronic Graft Versus Host Disease	Phase 1
Completed	`NCT01058239` - Bortezomib Plus Rituximab for EBV+ PTLD	Phase 2
Withdrawn	`NCT03327987` - Early Flu Shots in SOT
Recruiting	`NCT05164016` - Evaluating Immune Response to COVID-19 Vaccines in Patients With Cancer, Transplant or Cellular Therapy Recipients
Withdrawn	`NCT02464306` - Fidaxomicin Versus Standard of Care Therapy in Solid Organ Transplant Recipients With Clostridium Difficile Infection	Phase 4
Completed	`NCT02165423` - Discharge to Home and Chronic Illness Care Pilot	N/A
Completed	`NCT00907023` - Transition From Hospital to Home in Solid Organ Transplant (SOT)	N/A
Recruiting	`NCT04613206` - High vs. Standard Dose Influenza Vaccine in Adult SOT Recipients	Phase 2
Recruiting	`NCT05550298` - Multi-Center Molecular Diagnosis and Host Response of Respiratory Viral Infections in Pediatric Transplant Recipients
Completed	`NCT00518778` - Fusariosis in Solid-Organ Transplant Recipients	N/A
Active, not recruiting	`NCT04331275` - Viral Specific T-cells for Treatment of Viral Infections After Solid Organ Transplant	Phase 2
Recruiting	`NCT05968807` - iParent2Parent Program for Parents of Pediatric Solid Organ Transplant Recipients	N/A
Active, not recruiting	`NCT03482739` - Safety, Tolerability and Immunogenicity of a Nine-valent Human Papillomavirus (HPV) Vaccine in HIV and Transplant Patients	Phase 3
Not yet recruiting	`NCT04721288` - REmote moBile Outpatient mOnitoring in Transplant 2.0	N/A
Completed	`NCT04844489` - Study of the Humoral Response to SARS-CoV-2 Variants and of the Cellular Response After Vaccination Against COVID-19 in Immunocompromised People	N/A
Active, not recruiting	`NCT03360682` - Clinical Trial to Evaluate the Efficacy, Pharmacokinetics (PK) Interactions and Safety of Dolutegravir Plus 2 Nucleoside Reverse Transcriptase Inhibitors (NRTIs) in HIV‐1‐Infected Solid Organ Transplant Patients	Phase 4