Solid Cancers Clinical Trial
Official title:
Open-Label, Multicenter, Dose Escalation Phase Ib Study With Expansion Phase to Evaluate the Safety, Pharmacokinetics, and Activity of RO5509554 (Emactuzumab) and MPDL3280A (Atezolizumab) Administered in Combination in Patients With Advanced Solid Tumors
This Phase 1, open-label, multicenter, global study will evaluate the safety,
pharmacokinetics, and activity of emactuzumab and atezolizumab administered in combination in
participants with selected locally advanced or metastatic solid tumors that are not amenable
to standard treatment.
Participants who receive emactuzumab and atezolizumab will continue to receive study drug as
long as they experience clinical benefit in the opinion of the investigator or until
unacceptable toxicity or symptomatic deterioration attributed to disease progression as
determined by the investigator after an integrated assessment of radiographic data, biopsy
results (if available), and clinical status, or withdrawal of consent.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
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||
| Completed |
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|
Phase 1 |