Osteosarcoma Clinical Trial
Official title:
Combination of Pembrolizumab and Cabozantinib in Patients With Advanced Sarcomas
Phase II trial with three independent strata to independently assess the effects of the association of pembrolizumab and cabozantinib in advanced sarcomas.
3 independent, multicenter, prospective, signel-arm phase II trial, based on 2-stage Simon's optimal design, will be conducted in parallel to assess the efficacy of pembrolizumab + cabozantinib, in distinct populations of sarcomas: - stratum 1: advanced undiffenrentiated pleomorphic sarcoma - stratum 2: advanced osteosarcoma - stratum 3: advanced ewing sarcoma ;
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