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Low Dose Continuous Cyclophosphamide vs Standard Doxorubicin in Advanced Sarcoma Elderly Patients — METROPHOLYS  

Soft Tissue Sarcoma Adult Clinical Trial

Official title:
The METROPHOLYS Study Metronomic Cyclophosphamide vs Doxorubicin in Elderly Patients With Advanced Soft Tissue Sarcomas Randomized, Controlled Open Label Clinical Trial

Clinical Trial Summary

To compare the efficacy, as measured by time to treatment failure, of metronomic cyclophosphamide with respect to doxorubicin in elderly patients affected by mSTS.

Clinical Trial Description

This phase III randomized clinical trial was designed to compare metronomic Cyclophosphamide with standard Doxorubicin for the first-line treatment of elderly cancer patients with advanced inoperable or metastatic STS: i) ARM A (experimental): Metronomic Cyclophosphamide ii) ARM B (control): Doxorubicin up to six cycles ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04656262
Study type Interventional
Source Istituto Oncologico Veneto IRCCS
Contact Gian Luca De Salvo
Phone 0039-049-8215710
Email gianluca.desalvo@iov.veneto.it
Status Recruiting
Phase Phase 3
Start date September 10, 2018
Completion date January 31, 2023
View Details
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