Soft Tissue Injury Clinical Trial
Official title:
Elasticity Imaging of Soft Tissues
The purpose of this study is to evaluate the potential importance of tissue elasticity in
the assessment of soft tissues including muscles, tendons and ligaments and other soft
tissue structures.
The evaluation of tissue elasticity (easily stretched or moveable) may assist in assessment
of various soft tissue structures, such as fatty atrophy of muscles, tendon/ligamentous
injury and healing and other soft tissue structures.
This is a prospective study that will recruit males and females 18 years of age and older
who present to the department for a clinically indicated ultrasound of a superficial soft
tissue abnormality with prior or following MRI / CT assessment ordered for clinical
purposes.
The elasticity properties of tissues depend on their molecular building blocks and on the
organization of these blocks. Injuries, disease etc are known to be associated with changes
in tissue elasticity. Little research has been done on the potential of sonoelastographic
(elasticity ultrasound imaging) assessment of normal, injured or healing muscles, tendons or
ligaments.
Elasticity changes in muscle, ligaments and tendons following injury may have implication on
the choice of treatment and help in determine how the length of time needed to heal from an
injury.
Stiffness/elasticity of the tissue can be assessed by mechanical excitation with measurement
of resultant tissue motion. Reconstruction of the elastic deformability (strain imaging) in
real time ultrasound is known as sonoelastography.
Elasticity ultrasound imaging will be performed on the area being evaluated clinically.
;
Observational Model: Cohort, Time Perspective: Prospective
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT00537784 -
Platelet Concentrate in Achilles Tendon Repair
|
N/A | |
| Completed |
NCT02145130 -
Phase I Study for Autologous Dermal Substitutes and Dermo-epidermal Skin Substitutes for Treatment of Skin Defects
|
Phase 1 | |
| Terminated |
NCT00567528 -
Comparison of the Efficacy of Topical Ibuprofen to Oral Ibuprofen in Adolescent Athletes
|
N/A | |
| Withdrawn |
NCT01497678 -
Musculotendinous Tissue Unit Repair and Reinforcement (MTURR) Coordinating Center
|
N/A | |
| Recruiting |
NCT01063465 -
Measurement of Mechanical Properties of the Healing Achilles Tendon With or Without Early Weightbearing
|
N/A | |
| Completed |
NCT00264511 -
Hyperbaric Oxygen in Lower Leg Trauma
|
Phase 2/Phase 3 | |
| Completed |
NCT01292876 -
Musculotendinous Tissue Repair Unit and Reinforcement (MTURR)
|
N/A | |
| Completed |
NCT05026320 -
A Clinical Trial to Compare Safety and Effectiveness for Relieving Tenderness of 10% Naproxen Gel vs. a 2.32% Diclofenac Diethylamine Gel in the Treatment of Strains and Bruises of the Legs.
|
Phase 2 | |
| Completed |
NCT00931866 -
Diclofenac Patch for Treatment of Acute Pain Due to Mild to Moderate Soft Tissue Injuries (TAPED)
|
Phase 3 |