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Clinical Trial Summary

The purpose of this study is to examine whether experiencing a social stressor prior to the collection of neuroimaging measures is associated with differences in brain activation in healthy participants.


Clinical Trial Description

Using a randomized, parallel-group study design, this scientific investigation will examine the effect that experiencing the Trier Social Stress Test (TSST), the gold-standard for ethically inducing stress in a controlled laboratory setting, may have on neuroimaging measures of anxiety in healthy subjects. The study will enroll 50 healthy subjects who will be randomized to either experience the TSST or watch a nature film prior to undergoing task-based neuroimaging measures of emotional processing and self-referential processing using functional magnetic resonance imaging (fMRI). This study will be conducted primarily at Massachusetts Institute of Technology with research and clinical support from Massachusetts General Hospital. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05591404
Study type Interventional
Source Massachusetts Institute of Technology
Contact Omar Rutledge, MS
Phone 617-324-2898
Email orutledge@mit.edu
Status Not yet recruiting
Phase N/A
Start date December 2023
Completion date May 2025

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