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Social Phobia clinical trials

View clinical trials related to Social Phobia.

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NCT ID: NCT00182455 Terminated - Social Phobia Clinical Trials

Efficacy of Adding Topiramate to Current Treatment in Treatment-Resistant Generalized Social Phobia (GSP)

Start date: March 1, 2004
Phase: Phase 4
Study type: Interventional

SSRI's are considered first-line treatments for GSP, however many patients continue to have significant symptoms despite an adequate trial of an SSRI. Topiramate, a drug, which targets the glutamate system in the brain, has been shown to improve symptoms of social phobia when used on its own and has also been used as an additive treatment in other anxiety disorders. This study will test the efficacy of adding topiramate to a subject's current SSRI in cases of GSP which are considered to be treatment-resistant.

NCT ID: NCT00141115 Completed - Anxiety Disorders Clinical Trials

Levetiracetam for the Treatment of Alcohol Dependence and Anxiety

Start date: March 2004
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine if levetiracetam is effective in treating alcohol dependence in patients with anxiety symptoms. The researchers hypothesize that individuals are unable to reduce or discontinue alcohol use because of significant anxiety, mood, and sleep disturbance symptoms that accompany reduction in alcohol use.

NCT ID: NCT00128401 Completed - Anxiety Clinical Trials

Use of an Antibiotic as an Enhancer for the Treatment of Social Phobia

Start date: August 2005
Phase: Phase 2
Study type: Interventional

This study examines whether an antibiotic, d-cycloserine (DCS), boosts the effectiveness of cognitive behavior therapy (CBT) for social anxiety. CBT has been shown to be effective for the treatment of social anxiety in children and adults, but even after treatment, approximately 40% may remain diagnosable. The antibiotic DCS has been shown to enhance the type of learning that is promoted by exposure therapy, a main component of CBT. This study will test whether DCS can improve the effectiveness of CBT for social anxiety. All participants will receive 12 weekly CBT sessions. In addition to receiving the CBT, participants will be randomly assigned (similar to a coin toss) to receive either DCS or a placebo (sugar pill). The pill will be taken 1-2 hours prior to each of the 12 CBT sessions. The pill is taken only on the 12 therapy days. Prior to receiving treatment, participants will be asked to: - participate in interviews to assess diagnosis and how they are doing including mood, degree of nervousness and behavior - have a physical examination, a urine test, and an electrocardiogram (EKG) - undergo tests involving problem-solving and memory - prepare and present a speech to a "virtual audience" using virtual reality goggles - undergo functional magnetic resonance imaging (fMRI) while performing tasks that involve looking at pictures, remembering things, testing reaction times, and making simple choices Those who have not improved by the end of the study will be offered standard antianxiety medication treatment for 1 to 3 months. If a participant does not wish to take medication, study clinicians will help him/her locate psychological care in the community. Participants will be asked to complete a follow-up assessment 3 months after their last CBT session.

NCT ID: NCT00073333 Completed - Social Phobia Clinical Trials

Assessment and Treatment of Social Skills Deficits in Individuals With Social Phobia

Start date: December 2002
Phase: N/A
Study type: Interventional

This study will determine whether people with social phobia are deficient in certain social skills.

NCT ID: NCT00052078 Completed - Anxiety Disorders Clinical Trials

Child and Adolescent Anxiety Disorders (CAMS)

Start date: January 2003
Phase: Phase 3
Study type: Interventional

This randomized, controlled trial compared the efficacy of the medication sertraline (Zoloft®), cognitive-behavioral therapy, the combination of these treatments, and placebo for youth with anxiety disorders.

NCT ID: NCT00043537 Completed - Social Phobia Clinical Trials

Treatment of Childhood Social Phobia

Start date: April 2001
Phase: Phase 3
Study type: Interventional

This 4-year study will compare the long-term effectiveness of behavioral treatment, fluoxetine (Prozac®), and placebo for treatment of social phobia in children and adolescents.

NCT ID: NCT00012584 Completed - Clinical trials for Attention Deficit Hyperactivity Disorder

Treatment of Youth With ADHD and Anxiety

Start date: November 2000
Phase: N/A
Study type: Interventional

The purpose of this NIMH-sponsored pilot study is to collect information on the efficacy and safety of drug treatments for children and adolescents who suffer from both ADHD and anxiety disorders. Specifically, the study will examine the benefits of the stimulant medication both alone and in combination with fluvoxamine, a selective serotonin reuptake inhibitor (SSRI) that has antianxiety effects. Young people aged 6 to 17 diagnosed with these co-occurring disorders may be eligible to participate.

NCT ID: NCT00000389 Completed - Anxiety Disorders Clinical Trials

Treatment for Anxiety in Children

Start date: October 1996
Phase: Phase 3
Study type: Interventional

The purpose of this study is to see if it is effective to treat children with anxiety disorders with fluvoxamine. Fluvoxamine has been successfully used to treat obsessive-compulsive disorder (OCD) in adults and children. Anxiety disorders other than OCD, such as generalized anxiety disorder, social phobia, or separation anxiety, are very common in youth and are not always responsive to behavioral therapies alone. These disorders may respond to fluvoxamine. A child will be evaluated for 3 weeks before he/she is assigned randomly (like tossing a coin) to receive either fluvoxamine or an inactive placebo for 8 weeks. After this double-blind phase (neither the child/parents nor the doctor know which treatment is being given), the child will have the option of continuing treatment during a 4-month open-label extension period (both the child/parents and the doctor know which the child is receiving). A child may be eligible for this study if he/she: Is 6 to 17 years old and has been diagnosed with an anxiety disorder (i.e., generalized anxiety disorder, social phobia, or separation anxiety).

NCT ID: NCT00000370 Completed - Social Phobia Clinical Trials

Treatment of Social Phobia

Start date: May 1998
Phase: N/A
Study type: Interventional

Social phobia is a very common and debilitating disorder, with public speaking anxiety being the most common fear. Psychologists have found that treating patients for their fear of public speaking, through cognitive-behavioral treatment (talk-based therapy) or exposure treatment (where participants participate in actual public speaking sessions), not only helps patients overcome this fear but also helps them overcome their more general social fears. However, little is known about how this change occurs during therapy. This study tries to identify the factors that contribute most to successful therapy. Patients are assigned randomly (like tossing a coin) to 1 of 3 groups. Group 1 will receive cognitive-behavioral treatment and Group 2 will receive exposure treatment. Group 3 will not receive treatment. Study leaders will monitor patient response to treatment through behavioral tests and assessments. An individual may be eligible for this study if he/she: Has social phobia with public speaking anxiety.