Clinical Trials Logo

Clinical Trial Summary

Amyotrophic Lateral Sclerosis, also known as Charcot disease, is a neurodegenerative disease evidenced by gradual paralysis of the muscles involved in voluntary motor function. The clinical hallmark of Amyotrophic Lateral Sclerosis is the combination of upper and lower motor neuron signs and symptoms. The most recent studies suggest that up to 50% of Amyotrophic Lateral Sclerosis patients demonstrate mild to moderate cognitive disturbance. Impaired social cognition, including a deficit in the recognition of facial emotions and the identification of vocal prosody, is recognized as a part of the cognitive phenotype of Amyotrophic Lateral Sclerosis, with crucial implications for patients' and caregivers' training. However, studies remain scarce and the data acquired must be supported. The evolution of these manifestations during the disease is still poorly understood. In this study the investigators aim to assess the social cognition capacities of patients with Amyotrophic Lateral Sclerosis compared to healthy matched control subjects.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04406675
Study type Interventional
Source University Hospital, Angers
Contact Cassereau Julien
Phone 0241355615
Email jucassereau@chu-angers.fr
Status Recruiting
Phase N/A
Start date September 21, 2020
Completion date September 2023

See also
  Status Clinical Trial Phase
Completed NCT02566356 - Adult Study Oxytocin - fMRI Early Phase 1
Active, not recruiting NCT00747396 - The Bucharest Early Intervention Project N/A
Completed NCT02228031 - Oxytocin, Emotions and Mirror Neurons Early Phase 1
Completed NCT02567032 - Adult Study Oxytocin - Behavioral Early Phase 1
Recruiting NCT03035669 - Effects of Mindfulness Training on Emotion Regulation and Social Cognition. N/A
Completed NCT03775564 - Effectiveness of the RemedRugby Program N/A
Not yet recruiting NCT06213194 - The Effects of Executive Functions and Social Cognition on Mental Health N/A
Recruiting NCT05773872 - Evaluation of Social Cognition in Patient With Type 1 or Type 2 Narcolepsy Versus Patients With Idiopathic Hypersomnia N/A
Completed NCT05320991 - Effects of Ketamine on Mentalizing and Metacognition in Healthy Volunteers Phase 4
Recruiting NCT01903915 - Social Dysfunction and Brain Dysfunction in Patients With Schizophrenia N/A
Recruiting NCT05194254 - MRI-Eye Tracking Pairing, a Tool for Assessing Social Cognition in Children With ASD N/A
Completed NCT00884897 - Oxytocin and Social Cognition in Schizophrenia Phase 2
Completed NCT03450356 - The German Version of the Awareness of Social Inference Test
Not yet recruiting NCT03812913 - Neuropsychological Assessment of Children and Adolescents With Turner Syndrome
Completed NCT02568709 - Oxytocin MEG Study Early Phase 1
Completed NCT02652013 - Evaluation and Neural Basis of Communication in Patients With Multiple Sclerosis N/A
Completed NCT05866328 - Online TP (Training Program) on SC (Social Cognition) for Schizophrenia N/A
Completed NCT01616407 - Effects of MDMA and Methylphenidate on Social Cognition Early Phase 1
Completed NCT01206842 - Social Cognition Training in Schizophrenia N/A
Completed NCT02577575 - Adult Oxytocin Study Early Phase 1