Oxytocin Effects on Likeability After Being Liked or Disliked

Social Behavior Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02745431
• Other study ID #: UESTC-neuSCAN-06
• Status: Completed
• Phase: N/A
• First received: April 15, 2016
• Last updated: July 29, 2017
• Start date: June 2015
• Est. completion date: June 2016

Study information

• Verified date: November 2016
• Source: University of Electronic Science and Technology of China
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The current study aimed to investigate oxytocin effect on the response after the experience of being liked or disliked.

Description:

In a double-blind, between-subject, placebo controlled design study, the researchers aimed to investigate the intranasal OXT (40IU) treatment on rating response after being liked or disliked in healthy male subjects. All subjects completed a range of questionnaires measuring personality and affective traits and levels of anxiety: Positive and Negative Affect Schedule (PANAS) , State-Trait Anxiety Inventory (STAI) , Beck Depression Inventory (BDI), Cheek and Buss shyness Scale (CBSS),Autism Spectrum Quotient (ASQ), Empathy Quotient(EQ) before self-administration.Study participants were led to believe that other participants had formed an opinion on their likability based on their appearance in a photograph and they passively viewed the responses (like or dislike) from 'other participants'. After that, they rated 'other participants' about likeability (how much do you like the person), accuracy (have you seen the person), feeling (how good do you feel), and tendency (how much would do like have him/her as a friend). Likeability, tendency, feeling and accuracy were included into analysis as dependent variables.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 86
• Est. completion date: June 2016
• Est. primary completion date: June 2016
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 18 Years to 30 Years

Eligibility

Inclusion Criteria:

• Healthy subjects without past or current psychiatric or neurological disorder

Exclusion Criteria:

• history of head injury;

• claustrophobia;

• medical or psychiatric illness.

Related Conditions & MeSH terms

• Social Behavior

Intervention

Drug:
• Oxytocin

• Placebo

Locations

Country	Name	City	State
China	School of Life Science and Technology, University of Electronic Science and Technology	Chengdu	Sichuan

Sponsors (1)

Lead Sponsor	Collaborator
University of Electronic Science and Technology of China

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Oxytocin effect on likeability after being liked or disliked	Likeability rating was included into analysis as dependent factor.	2 hour
Secondary	Relationship status may influence oxytocin effect	subjects were subdivided into two subgroups	2 hour